Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Libo Yu-Taeger"'
Autor:
Ilham El Atiallah, Giulia Ponterio, Maria Meringolo, Giuseppina Martella, Giuseppe Sciamanna, Annalisa Tassone, Martina Montanari, Maria Mancini, Antonio N. Castagno, Libo Yu-Taeger, Hoa Huu Phuc Nguyen, Paola Bonsi, Antonio Pisani
Publikováno v:
Neurobiology of Disease, Vol 191, Iss , Pp 106403- (2024)
Loss-of-function mutations in the GNAL gene are responsible for DYT-GNAL dystonia. However, how GNAL mutations contribute to synaptic dysfunction is still unclear. The GNAL gene encodes the Gαolf protein, an isoform of stimulatory Gαs enriched in t
Externí odkaz:
https://doaj.org/article/d66a430f7a5746dd9ce4d4567c815918
Publikováno v:
Cells, Vol 13, Iss 6, p 469 (2024)
Huntington’s disease (HD), a congenital neurodegenerative disorder, extends its pathological damages beyond the nervous system. The systematic manifestation of HD has been extensively described in numerous studies, including dysfunction in peripher
Externí odkaz:
https://doaj.org/article/68c0c184414a4ba697ff84266ce72fe3
Autor:
Libo Yu-Taeger, Arianna Novati, Jonasz Jeremiasz Weber, Elisabeth Singer-Mikosch, Ann-Sophie Pabst, Fubo Cheng, Carsten Saft, Jennifer Koenig, Gisa Ellrichmann, Taneli Heikkinen, Mahmoud A. Pouladi, Olaf Riess, Huu Phuc Nguyen
Publikováno v:
Cells, Vol 11, Iss 23, p 3779 (2022)
Body weight (BW) loss and reduced body mass index (BMI) are the most common peripheral alterations in Huntington disease (HD) and have been found in HD mutation carriers and HD animal models before the manifestation of neurological symptoms. This sug
Externí odkaz:
https://doaj.org/article/182d9543377f43cc8144fbbfc702c74e
Autor:
Libo Yu-Taeger, Thomas Ott, Paola Bonsi, Celina Tomczak, Zinah Wassouf, Giuseppina Martella, Giuseppe Sciamanna, Paola Imbriani, Giulia Ponterio, Annalisa Tassone, Julia M. Schulze-Hentrich, Rose Goodchild, Olaf Riess, Antonio Pisani, Kathrin Grundmann-Hauser, Huu Phuc Nguyen
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
Dystonia is a neurological movement disorder characterized by sustained or intermittent involuntary muscle contractions. Loss-of-function mutations in the GNAL gene have been identified to be the cause of “isolated” dystonia DYT25. The GNAL gene
Externí odkaz:
https://doaj.org/article/8a71ddea79364ff685249d5e5644b2ff
Autor:
Libo Yu-Taeger, Viktoria Gaiser, Larissa Lotzer, Tina Roenisch, Benedikt Timo Fabry, Janice Stricker-Shaver, Nicolas Casadei, Michael Walter, Martin Schaller, Olaf Riess, Huu Phuc Nguyen, Thomas Ott, Kathrin Grundmann-Hauser
Publikováno v:
Biology Open, Vol 7, Iss 7 (2018)
A three-base-pair deletion in the human TOR1A gene is causative for the most common form of primary dystonia: the early-onset dystonia type 1 (DYT1 dystonia). The pathophysiological consequences of this mutation are still unknown. To study the pathol
Externí odkaz:
https://doaj.org/article/012b988e3f124b999acb2b9f84455cd4
Autor:
Arianna Novati, Libo Yu-Taeger, Irene Gonzalez Menendez, Leticia Quintanilla Martinez, Huu Phuc Nguyen
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198338 (2018)
BACKGROUND:Huntington disease (HD) is an autosomal dominant neurodegenerative disorder caused by a mutation in the huntingtin (HTT) gene, which results in brain neurodegeneration and peripheral pathology affecting different organs including testis. P
Externí odkaz:
https://doaj.org/article/c0e1405fca6844bbb8e112bdad3c6689
Autor:
Libo Yu-Taeger, Janice Stricker-Shaver, Katrin Arnold, Patrycja Bambynek-Dziuk, Arianna Novati, Elisabeth Singer, Ali Lourhmati, Claire Fabian, Janine Magg, Olaf Riess, Matthias Schwab, Alexandra Stolzing, Lusine Danielyan, Hoa Huu Phuc Nguyen
Publikováno v:
Cells, Vol 8, Iss 6, p 595 (2019)
Intrastriatal administration of mesenchymal stem cells (MSCs) has shown beneficial effects in rodent models of Huntington disease (HD). However, the invasive nature of surgical procedure and its potential to trigger the host immune response may limit
Externí odkaz:
https://doaj.org/article/a1cc28f483b44180a8ee4c7e39c3904f
Autor:
Nicole El Massioui, Charlotte Lamirault, Sara Yagüe, Najia Adjeroud, Daniel Garces, Alexis Maillard, Lucille Tallot, Libo Yu-Taeger, Olaf Riess, Philippe Allain, Huu Phuc Nguyen, Stephan Von Hörsten, Valérie Doyère
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 10 (2016)
Cognitive deficits associated with Huntington disease (HD) are generally dominated by executive function disorders often associated with disinhibition and impulsivity/compulsivity. Few studies have directly examined symptoms and consequences of behav
Externí odkaz:
https://doaj.org/article/f59386a3d1b14450a028cf7a14b68b3d
Autor:
Caroline Gouarné, Gwenaëlle Tardif, Jennifer Tracz, Virginie Latyszenok, Magali Michaud, Laura Emily Clemens, Libo Yu-Taeger, Huu Phuc Nguyen, Thierry Bordet, Rebecca M Pruss
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81528 (2013)
In Huntington disease (HD), there is increasing evidence for a link between mutant huntingtin expression, mitochondrial dysfunction, energetic deficits and neurodegeneration but the precise nature, causes and order of these events remain to be determ
Externí odkaz:
https://doaj.org/article/7498c9b36102411c84a7856ce01a6124
Autor:
Fubo, Cheng, Wenxu, Zheng, Chang, Liu, Peter Antony, Barbuti, Libo, Yu-Taeger, Nicolas, Casadei, Jeannette, Huebener-Schmid, Jakob, Admard, Karsten, Boldt, Katrin, Junger, Marius, Ueffing, Henry, Houlden, Manu, Sharma, Rejko, Kruger, Kathrin, Grundmann-Hauser, Thomas, Ott, Olaf, Riess
Publikováno v:
Science advances. 8(47)
Evidence from patients with Parkinson's disease (PD) and our previously reported α-synuclein (SNCA) transgenic rat model support the idea that increased SNCA protein is a substantial risk factor of PD pathogenesis. However, little is known about the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ec6c460c746d06a2cf050bfe8c370a9
https://pubmed.ncbi.nlm.nih.gov/36417521
https://pubmed.ncbi.nlm.nih.gov/36417521