Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Libia F Scheller"'
Publikováno v:
Infection and Immunity. 65:3882-3888
The elimination of liver-stage malaria parasites by nitric oxide (NO)-producing hepatocytes is regulated by T cells. Both CD8+ and CD4+ T cells, which surround infected hepatocytes, are evident by 24 h after sporozoite challenge in Brown Norway rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9ab54e54b022d58a449c83a2f52ad2
https://doi.org/10.1128/iai.65.9.3882-3888.1997
https://doi.org/10.1128/iai.65.9.3882-3888.1997
Autor:
Denise L. Doolan, Jon Norman, Thong P. Le, Libia F Scheller, Stephen L. Hoffman, Ruobing Wang, Dennis M. Klinman, Richard C. Hedstrom, Peter Hobart, Martha Sedegah, Anita Kumar, Walter R. Weiss
Publikováno v:
Immunology and Cell Biology. 75:376-381
In mid 1997 the first malaria DNA vaccine will enter clinical trials. This single gene DNA vaccine encoding the Plasmodium falciparum circumsporozoite protein (PfCSP) will be studied for safety and immunogenicity. If these criteria are met, a multi-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d9084314f9a4968dcc99dbaccf6868
https://doi.org/10.1038/icb.1997.59
https://doi.org/10.1038/icb.1997.59
Publikováno v:
Infection and Immunity. 62:4844-4847
Despite the low susceptibility of BALB/c mice to hepatic infection by Plasmodium berghei, this animal model is routinely used to investigate the basic biology of the malaria parasite and to test vaccines and the immune response against exoerythrocyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::770bf4a6695a6831a84b0745117c8942
https://doi.org/10.1128/iai.62.11.4844-4847.1994
https://doi.org/10.1128/iai.62.11.4844-4847.1994
Plasmodium berghei sporozoites delivered by mosquito bite were more infectious to outbred CD-1 mice than were sporozoites delivered by intravenous inoculation. The route of challenge also affected vaccine efficacy. In view of these findings and the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20f729c90076626500d4beaa353f506
https://europepmc.org/articles/PMC96740/
https://europepmc.org/articles/PMC96740/
Autor:
Abdu F. Azad, Libia F. Scheller
Immunization of rodents and humans with irradiation-attenuated malaria sporozoites confers preerythrocytic stage-specific protective immunity to challenge infection. This immunity is directed against intrahepatic parasites and involves T cells and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839ed24ff57aa8ac0b14403faabc6cfe
https://europepmc.org/articles/PMC42103/
https://europepmc.org/articles/PMC42103/
Autor:
Libia F. Scheller, F W Klotz, Carol A. Nacy, Matthew C. Seguin, Michael A. Marletta, Barbara J. Nelson, Shawn J. Green, Mike Slayter
Publikováno v:
Immunology letters. 43(1-2)
To discover how nitric oxide (NO) synthesis is controlled in different tissues as cells within these tissues combat intracellular pathogens, we examined three distinctively different experimental murine models designed for studying parasite-host inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69adc351a117f8250a2d313154ff59bf
https://pubmed.ncbi.nlm.nih.gov/7537721
https://pubmed.ncbi.nlm.nih.gov/7537721
Publikováno v:
The Journal of Parasitology. 81:58
Immunization with irradiated-attenuated malaria sporozoites has been shown to protect both rodents and humans against a homologous sporozoite challenge. Irradiated-attenuated sporozoites retain their capacity to invade hepatocytes and transform into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25480b9da44c4bb5ef07e6add1fdf757
https://doi.org/10.2307/3284006
https://doi.org/10.2307/3284006