Výsledky vyhledávání - "Libby Kindle"

Stromal cell-derived factor-1 binding to its chemokine receptor CXCR4 on precursor cells promotes the chemotactic recruitment, development and survival of human osteoclasts

Autor: William F. Maloney, Libby Kindle, Lorinda M. Wright, Xuefeng Yu, Patricia Collin-Osdoby, Philip Osdoby

Publikováno v: Bone. 36:840-853

Osteoclasts (Oc) derive from hematopoietic precursors present in the circulation and bone marrow, and they differentiate into multinucleated bone-resorbing cells in response to the dual essential signals receptor activator of NF-kappaB ligand (RANKL)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d55cc280ab1ccf39f5f260e285e7051
https://doi.org/10.1016/j.bone.2005.01.021

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Human microvascular endothelial cell activation by IL-1 and TNF-alpha stimulates the adhesion and transendothelial migration of circulating human CD14+ monocytes that develop with RANKL into functional osteoclasts

Autor: Linda Rothe, Patricia Collin-Osdoby, Philip Osdoby, Libby Kindle, Michael Kriss

Publikováno v: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 21(2)

Circulating pre-OCs may be recruited to locally inflamed sites through specific interactions with activated microvasculature. We found that HMVECs stimulated the adhesion and TEM of circulating pre-OCs, in an ICAM-1- and CD44-dependent manner, leadin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d157daf8d82cc3316c8f1461e7934100
https://pubmed.ncbi.nlm.nih.gov/16418775

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