Single-cell RNA sequencing of cystic fibrosis liver disease explants reveals endothelial complement activation.

Autor: Declercq M; Department of Development and Regeneration, Woman and Child Unit, KU Leuven, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium., Treps L; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium.; Nantes Université, INSERM UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, Nantes, France., Geldhof V; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium., Conchinha NV; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium.; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal., de Rooij LPMH; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium.; The CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Subramanian A; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium.; Department of Biotechnology, Indian Institute of Technology, Hyderabad, Telangana, India., Feyeux M; Nantes Université, CHU Nantes, CNRS, Inserm, BioCore, US16, SFR Bonamy, Nantes, France., Cotinat M; Nantes Université, INSERM UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, Nantes, France., Boeckx B; Laboratory for Translational Genetics, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium., Vinckier S; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium., Dupont L; Department of Pneumology, UZ Leuven, Leuven, Belgium.; Department of Chronic Diseases and Metabolism, Respiratory Diseases and Thoracic Surgery, KU Leuven, Leuven, Belgium., Vermeulen F; Department of Development and Regeneration, Woman and Child Unit, KU Leuven, Leuven, Belgium.; Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium., Boon M; Department of Development and Regeneration, Woman and Child Unit, KU Leuven, Leuven, Belgium.; Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium., Proesmans M; Department of Development and Regeneration, Woman and Child Unit, KU Leuven, Leuven, Belgium.; Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium., Libbrecht L; Department of Pathology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.; Department of Pathology, AZ Groeninge, Kortrijk, Belgium.; Laboratory of Hepatology, KU Leuven, Leuven, Belgium., Pirenne J; Transplantation Research Group, Department of Immunology, Microbiology and Transplantation, KU Leuven, Leuven, Belgium.; Department of Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium., Monbaliu D; Transplantation Research Group, Department of Immunology, Microbiology and Transplantation, KU Leuven, Leuven, Belgium.; Department of Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium., Jochmans I; Transplantation Research Group, Department of Immunology, Microbiology and Transplantation, KU Leuven, Leuven, Belgium.; Department of Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium., Dewerchin M; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium., Eelen G; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium., Roskams T; Department of Imaging and Pathology, Translational Cell and Tissue Research, KU Leuven and University Hospitals Leuven, Leuven, Belgium., Verleden S; Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department CHROMETA, KU Leuven, Leuven, Belgium.; Department of ASTARC, University of Antwerp, Wilrijk, Belgium., Lambrechts D; Laboratory for Translational Genetics, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium., Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium.; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates., Witters P; Department of Development and Regeneration, Woman and Child Unit, KU Leuven, Leuven, Belgium.; Department of Paediatrics and Metabolic Center, University Hospitals Leuven, Leuven, Belgium.

Publikováno v: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2024 Sep; Vol. 44 (9), pp. 2382-2395. Date of Electronic Publication: 2024 Jun 07.

YAP1::NR4A3 and YAP1::NCOA2 fusions in poroma: expanding the spectrum of molecular alterations in poroid tumors.

Autor: Secco LP; Department of Pathology, Cliniques Universitaires Saint-Luc, B-1200, Brussels, Belgium., Libbrecht L; Department of Pathology, Cliniques Universitaires Saint-Luc, B-1200, Brussels, Belgium.; Department of Pathology, AZ Groeninge, B-1200, Kortrijk, Belgium., Bonny M; Department of Dermatology, AZ Groeninge Kortrijk, Kortrijk, Belgium., Lepine C; Department of Pathology, University Hospital of Nantes, Nantes University, Nantes, France.; Immunology and New Concepts in ImmunoTherapy (INCIT), Inserm, CNRS, UMR 1302/EMR6001, Nantes, France., Švajdler M; Department of Pathology, Faculty of Medicine in Plzen, Charles University, Prague, Czech Republic., Tallet A; Platform of Somatic Tumour Molecular Genetics, Université de Tours, Centre Hospitalier Universitaire de Tours, Tours, France., Chantreau PL; Platform of Somatic Tumour Molecular Genetics, Université de Tours, Centre Hospitalier Universitaire de Tours, Tours, France., Cormier B; IHP Groupe, Tours, France., Cribier B; Clinique Dermatologique, Hôpital Civil, Hôpitaux Universitaires, Université de Strasbourg, Strasbourg, France.; CARADERM, French Network of Rare Cutaneous Cancer, Lille, France., Siozopoulou V; Department of Pathology, Cliniques Universitaires Saint-Luc, B-1200, Brussels, Belgium., Kervarrec T; CARADERM, French Network of Rare Cutaneous Cancer, Lille, France. thibaultkervarrec@yahoo.fr.; Department of Pathology, University Hospital of Tours, 37044, Tours Cedex 09, France. thibaultkervarrec@yahoo.fr.; 'Biologie Des Infections À Polyomavirus' Team, UMR1282 INRAE, University of Tours, Tours, France. thibaultkervarrec@yahoo.fr.

Publikováno v: Virchows Archiv : an international journal of pathology [Virchows Arch] 2024 Oct; Vol. 485 (4), pp. 749-753. Date of Electronic Publication: 2024 Aug 23.

Breast-implant Related Silicone Lymphadenopathy: Asteroid Bodies do not Always Equal Sarcoidosis!

Autor: Van Bockstal MR; Department of Pathology, Cliniques universitaires Saint-Luc, Avenue Hippocrate 10, 1200, Brussels, Belgium.; Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Avenue Hippocrate 10, 1200, Brussels, Belgium., Libbrecht L; Department of Pathology, Cliniques universitaires Saint-Luc, Avenue Hippocrate 10, 1200, Brussels, Belgium.; Department of Pathology, AZ Groeninge, President Kennedylaan 4, 8500, Kortrijk, Belgium., Dubail A; Department of Pathology, Cliniques universitaires Saint-Luc, Avenue Hippocrate 10, 1200, Brussels, Belgium., Berlière M; Breast Clinic, King Albert II Cancer Institute, Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10, 1200, Brussels, Belgium., Galant C; Department of Pathology, Cliniques universitaires Saint-Luc, Avenue Hippocrate 10, 1200, Brussels, Belgium.; Department of Pathology, AZ Groeninge, President Kennedylaan 4, 8500, Kortrijk, Belgium.

Publikováno v: International journal of surgical pathology [Int J Surg Pathol] 2023 Sep; Vol. 31 (6), pp. 1099-1104. Date of Electronic Publication: 2022 Oct 30.

The Distinct Innate Immune Response of Warm Ischemic Injured Livers during Continuous Normothermic Machine Perfusion.

Autor: Blondeel J; Department of Abdominal Transplant Surgery and Transplant Coordination, University Hospitals Leuven, 3000 Leuven, Belgium.; Laboratory of Abdominal Transplantation, Department of Microbiology, Immunology and Transplantation, KU Leuven, 3000 Leuven, Belgium., Gilbo N; Department of Abdominal Transplant Surgery and Transplant Coordination, University Hospitals Leuven, 3000 Leuven, Belgium.; Laboratory of Abdominal Transplantation, Department of Microbiology, Immunology and Transplantation, KU Leuven, 3000 Leuven, Belgium., Heedfeld V; Department of Abdominal Transplant Surgery and Transplant Coordination, University Hospitals Leuven, 3000 Leuven, Belgium.; Laboratory of Abdominal Transplantation, Department of Microbiology, Immunology and Transplantation, KU Leuven, 3000 Leuven, Belgium., Wylin T; Department of Abdominal Transplant Surgery and Transplant Coordination, University Hospitals Leuven, 3000 Leuven, Belgium.; Laboratory of Abdominal Transplantation, Department of Microbiology, Immunology and Transplantation, KU Leuven, 3000 Leuven, Belgium., Libbrecht L; Department of Pathology, AZ Groeninge, 8500 Kortrijk, Belgium.; Laboratory of Hepatology, CHROMETA Department, KU Leuven, 3000 Leuven, Belgium., Jochmans I; Department of Abdominal Transplant Surgery and Transplant Coordination, University Hospitals Leuven, 3000 Leuven, Belgium.; Laboratory of Abdominal Transplantation, Department of Microbiology, Immunology and Transplantation, KU Leuven, 3000 Leuven, Belgium., Pirenne J; Department of Abdominal Transplant Surgery and Transplant Coordination, University Hospitals Leuven, 3000 Leuven, Belgium.; Laboratory of Abdominal Transplantation, Department of Microbiology, Immunology and Transplantation, KU Leuven, 3000 Leuven, Belgium., Korf H; Laboratory of Hepatology, CHROMETA Department, KU Leuven, 3000 Leuven, Belgium., Monbaliu D; Department of Abdominal Transplant Surgery and Transplant Coordination, University Hospitals Leuven, 3000 Leuven, Belgium.; Laboratory of Abdominal Transplantation, Department of Microbiology, Immunology and Transplantation, KU Leuven, 3000 Leuven, Belgium.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 16; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 16.

A yellow sign indicating danger ahead.

Autor: Billiet A; Department of Gastroenterology and Hepatology, University Hospitals KU Leuven, Leuven, Belgium., Moubax K; Department of Gastroenterology and Hepatology , AZ Groeninge, Kortrijk, Belgium., Libbrecht L; Department of Pathology , AZ Groeninge, Kortrijk, Belgium., Van Moerkercke W; Department of Gastroenterology and Hepatology , AZ Groeninge, Kortrijk, Belgium.

Publikováno v: Acta gastro-enterologica Belgica [Acta Gastroenterol Belg] 2022 Oct-Dec; Vol. 85 (4), pp. 654-655.