Full or Partial Substitution of the Reactive Center Loop of α-1-Proteinase Inhibition.

Autor: Filion, Marc L., Bhakta, Varsha, Nguyen, Laurie H., Liaw, Peter S., Sheffield, William P.

Publikováno v: Biochemistry; 11/23/2004, Vol. 43 Issue 46, p14864-14872, 9p

Full or partial substitution of the reactive center loop of alpha-1-proteinase inhibitor by that of heparin cofactor II: P1 Arg is required for maximal thrombin inhibition.

Autor: Filion ML; Department of Pathology and Molecular Medicine, McMaster University, HSC-4N66, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada., Bhakta V, Nguyen LH, Liaw PS, Sheffield WP

Publikováno v: Biochemistry [Biochemistry] 2004 Nov 23; Vol. 43 (46), pp. 14864-72.