Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Lianru Zhang"'
Autor:
Yanhong Chu, Lingyu Qian, Yaohua Ke, Xiaoyu Feng, Xinjie Chen, Fangcen Liu, Lixia Yu, Lianru Zhang, Yaping Tao, Rui Xu, Jia Wei, Baorui Liu, Qin Liu
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Neoantigens are considered ideal targets for immunotherapy, especially tumor vaccine, because of their strong specificity and immunogenicity. Here, we developed a neoantigen nanovaccine used liposomes with lymph-node targeting cha
Externí odkaz:
https://doaj.org/article/1bb46e64ca604c01b60133b3c3e42dd2
Autor:
Yishan Li, Lianru Zhang, Huiping Yu, Xiaoyan Xin, Jian He, Yongzhong Yao, Baorui Liu, Rutian Li, Li Xie
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Breast cancer is considered a malignant tumor with the highest incidence among women and is prone to develop distant metastasis. Small intestinal metastasis of breast cancer, however, is relatively rare. This case report describes a 49-year-old Chine
Externí odkaz:
https://doaj.org/article/64af9c3bad1346228527cc3e6b134ae5
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Breast cancer remains the most frequently diagnosed malignancy worldwide. Advanced breast cancer is still an incurable disease mainly because of its heterogeneity and limited immunogenicity. The great success of cancer immunotherapy is paving the way
Externí odkaz:
https://doaj.org/article/ca7a629105064ee8966ddabc86ad5ebc
Autor:
Naiqing Ding, Zhengyun Zou, Huizi Sha, Shu Su, Hanqing Qian, Fanyan Meng, Fangjun Chen, Shiyao Du, Shujuan Zhou, Hong Chen, Lianru Zhang, Ju Yang, Jia Wei, Baorui Liu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
The therapeutic efficacy of adoptive T cell transfer is limited by their ability to infiltrate solid tumours. Here, the authors show that loading the tumor penetrating cyclic peptide iRGD on the cell surface of T cells enhances their ability to penet
Externí odkaz:
https://doaj.org/article/4d424ce982544f98bbf28d7feda3ba49
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selectively kills tumor cells and augments chemotherapeutics in vivo. Here, we developed sTRAIL-iRGD, a recombinant protein consisting of sTRAIL fused to CRGDKGPDC, a C-terminal
Externí odkaz:
https://doaj.org/article/ab725ef9bbca40aba2422b2ad0085119
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 7, Iss 1, Pp 91-96 (2017)
The aims of the present study were to estimate the affinity between 3,5-(E)-bis(3-methoxy-4-hydroxybenzal)-4-piperidinone hydrochloride (C0818) and heat shock protein 90 (Hsp90) and to investigate the inhibitory effects of this compound on Hsp90 ATPa
Externí odkaz:
https://doaj.org/article/cfa83402e5b145ab8e3994c3a4e1c5e1
Autor:
Qin Liu, Zhichen Sun, Jiaqi Xie, Kangxin Wang, Siyi Tan, Xuebin Zhang, Baorui Liu, Yang Yang, Jia Wei, Lianru Zhang, Lihua Yuan, Yiwen Xu
Publikováno v:
Cancer Management and Research
Kangxin Wang,1,2,* Xuebin Zhang,3,* Jia Wei,1 Yiwen Xu,4 Qin Liu,1 Jiaqi Xie,1 Lihua Yuan,3 Zhichen Sun,1 Siyi Tan,1 Lianru Zhang,1 Baorui Liu,1 Yang Yang1 1The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc390ca131b6a7d9a41c35a5d39d66a
https://doi.org/10.2147/cmar.s233123
https://doi.org/10.2147/cmar.s233123
Autor:
Yanhong Chu, Lingyu Qian, Yaohua Ke, Xiaoyu Feng, Xinjie Chen, Fangcen Liu, Lixia Yu, Lianru Zhang, Yaping Tao, Rui Xu, Jia Wei, Baorui Liu, Qin Liu
Publikováno v:
Journal of nanobiotechnology. 20(1)
Background Neoantigens are considered ideal targets for immunotherapy, especially tumor vaccine, because of their strong specificity and immunogenicity. Here, we developed a neoantigen nanovaccine used liposomes with lymph-node targeting characterist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b645e15db13d23fc3901fe425e2010
https://pubmed.ncbi.nlm.nih.gov/35418151
https://pubmed.ncbi.nlm.nih.gov/35418151
Publikováno v:
Cancer Management and Research. 11:8937-8945
Purpose Inhibition of heat shock protein 90 (Hsp90) can lead to degradation of multiple client proteins, which are involved in tumor progression. Elevated Hsp90 expression has been linked to poor prognosis in patients with non-small cell lung cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d31962cc0212fc0b1547dd12d9e8a407
https://doi.org/10.2147/cmar.s215970
https://doi.org/10.2147/cmar.s215970
Autor:
Hong Chen, Jia Wei, Naiqing Ding, Lianru Zhang, Shiyao Du, Ju Yang, Zhengyun Zou, Shu Su, Fangjun Chen, Hanqing Qian, Huizi Sha, Baorui Liu, Shujuan Zhou, Fanyan Meng
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Nature Communications
Nature Communications
Poor infiltration of activated lymphocytes into tumors represents a fundamental factor limiting the therapeutic effect of adoptive cell immunotherapy. A tumor-penetrating peptide, iRGD, has been widely used to deliver drugs into tumor tissues. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a53aeda5a9755af21865dda7f02d24e
https://doaj.org/article/4d424ce982544f98bbf28d7feda3ba49
https://doaj.org/article/4d424ce982544f98bbf28d7feda3ba49