Výsledky vyhledávání - "Lianne van de Laar"

Comparison of the PU.1 transcriptional regulome and interactome in human and mouse inflammatory dendritic cells

Autor: Vishal Salunkhe, Sjaak Philipsen, Rutger W W Brouwer, Timo K. van den Berg, Nynke Gillemans, Jeroen Demmers, Lianne van de Laar, Erikjan Rijkers, Wilfred F. J. van IJcken, Noemí Caballero-Sánchez, Iris M. De Cuyper, Pieter De Bleser, Maaike R. Scheenstra, Laura Gutierrez, Andrea Acebes-Huerta, Patricia Martínez-Botía, Benjamin Nota, Andrea M. Woltman, Taco W. Kuijpers

Publikováno v: RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Journal of leukocyte biology, 110(4), 735-751. FASEB
Journal of Leukocyte Biology, 1-17. John Wiley & Sons Inc.
STARTPAGE=1;ENDPAGE=17;ISSN=0741-5400;TITLE=Journal of Leukocyte Biology

Dendritic cells (DCs) are key immune modulators and are able to mount immune responses or tolerance. DC differentiation and activation imply a plethora of molecular and cellular responses, including transcriptional changes. PU.1 is a highly expressed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948526b0e9c69ecf828402662f0b66b5
http://hdl.handle.net/10651/57182

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Yolk Sac Macrophages, Fetal Liver, and Adult Monocytes Can Colonize an Empty Niche and Develop into Functional Tissue-Resident Macrophages

Autor: Sofie De Prijck, Bart N. Lambrecht, Rudi Beyaert, Eik Hoffmann, Charlotte L. Scott, Liesbet Martens, Yvan Saeys, Martin Guilliams, Gert Van Isterdael, Wouter Saelens, Lianne van de Laar

Publikováno v: Immunity, 44(4), 755-768. Cell Press

Tissue-resident macrophages can derive from yolk sac macrophages (YS-Macs), fetal liver monocytes (FL-MOs), or adult bone-marrow monocytes (BM-MOs). The relative capacity of these precursors to colonize a niche, self-maintain, and perform tissue-spec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e0a9ca5c65369df1a236ff95940081
https://doi.org/10.1016/j.immuni.2016.02.017

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BDCA3 expression is associated with high IFN-λ production by CD34+-derived dendritic cells generated in the presence of GM-CSF, IL-4, and/or TGF-β

Autor: Harry L.A. Janssen, Andrea M. Woltman, Nadine van Montfoort, Lianne van de Laar, Evelyn van der Aa

Publikováno v: European Journal of Immunology. 45:1471-1481

High BDCA3 expression is associated with a specific human IFN-λ-producing dendritic cell (DC) subset. However, BDCA3 has also been detected on other DC subsets. Thus far, development and function of BDCA3 expression on DCs remains poorly understood.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b052b928434cc0c55f456ef0ced727f
https://doi.org/10.1002/eji.201444802

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Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival

Autor: Eef Parthoens, Takao Iwawaki, Karl Vergote, Bart N. Lambrecht, Lianne van de Laar, Riet De Rycke, Sophie Janssens, Nele Vanlangenakker, Lana Vandersarren, Simon Tavernier, Jessica Vetters, Chih-Chi Andrew Hu, Juan R. Del Valle, Gert Van Isterdael, Fabiola Osorio

Publikováno v: Nature Cell Biology, 19(6), 698-+. Nature Publishing Group

The IRE1-XBP1 signalling pathway is part of a cellular programme that protects against endoplasmic reticulum (ER) stress, but also controls development and survival of immune cells. Loss of XBP1 in splenic type 1 conventional dendritic cells (cDC1s)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4053026f09e8c16be5d68195f4900d
https://pure.eur.nl/en/publications/2e6a8da5-fe12-4fb7-9e8b-50a8628d2655

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Isolation of Conventional Dendritic Cells from Mouse Lungs

Autor: Lianne, van de Laar, Martin, Guilliams, Simon, Tavernier

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1423

The lungs are in direct contact with the environment. Separated only by a thin layer of mucosa, the lung immune system is being exposed to dangers like pathogens, allergens, or pollutants. The lung dendritic cells form an elaborate network at the bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5c714c731e6999b1b0de4e22adbd2c14
https://pubmed.ncbi.nlm.nih.gov/27142014

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Isolation of Conventional Dendritic Cells from Mouse Lungs

Autor: Martin Guilliams, Simon Tavernier, Lianne van de Laar

Publikováno v: Methods in Molecular Biology ISBN: 9781493936045

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b289d8c0ad928373d0dd88ff77f75cb4
https://doi.org/10.1007/978-1-4939-3606-9_10

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PI3K-PKB hyperactivation augments human plasmacytoid dendritic cell development and function

Autor: Lianne van de Laar, Rekha S. Binda, Aniek van den Bosch, Andre Boonstra, Harry L.A. Janssen, Miranda Buitenhuis, Paul J. Coffer, Andrea M. Woltman

Publikováno v: Blood, 120(25), 4982-4991. American Society of Hematology

Plasmacytoid dendritic cells (pDCs) are considered potential tools or targets for immunotherapy. However, current knowledge concerning methodologies to manipulate their development or function remains limited. Here, we investigated the role of the ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e01853d8e12ebced0e4aa36df981aa
https://doi.org/10.1182/blood-2012-02-413229

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How to generate large numbers of CD103(+) dendritic cells

Autor: Lianne van de Laar, Bart N. Lambrecht

Publikováno v: Blood, 124(20), 3036-3038. American Society of Hematology

In this issue of Blood, Mayer et al describe a new method of generating high numbers of Batf3- and Irf8-dependent CD103+ conventional dendritic cells (cDCs), providing new opportunities to study this subset of antigen-presenting cells specialized in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9262c325e3dd367f57f3af86f1942c77
https://doi.org/10.1182/blood-2014-08-595298

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A Nonredundant Role for Canonical NF-kappa B in Human Myeloid Dendritic Cell Development and Function

Autor: Harry L.A. Janssen, Aniek van den Bosch, Sandra W. van der Kooij, Lianne van de Laar, Andrea M. Woltman, Cees van Kooten, Paul J. Coffer

Publikováno v: Journal of Immunology, 185(12), 7252-7261. American Association of Immunologists

The plastic role of dendritic cells (DCs) in the regulation of immune responses has made them interesting targets for immunotherapy, but also for pathogens or tumors to evade immunity. Functional alterations of DCs are often ascribed to manipulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de751eee4519c69672c7b783f21cc355
https://pure.eur.nl/en/publications/38fce565-99f9-48d4-a009-d88208bdd759

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Human CD34-Derived Myeloid Dendritic Cell Development Requires Intact Phosphatidylinositol 3-Kinase-Protein Kinase B-Mammalian Target of Rapamycin Signaling

Autor: Lianne van de Laar, Felix M. Wensveen, Andrea M. Woltman, Harry L.A. Janssen, Paul J. Coffer, Miranda Buitenhuis

Publikováno v: Journal of immunology (Baltimore, Md., 184(12), 6600-6611. American Association of Immunologists
Journal of Immunology, 184(12), 6600-6611. American Association of Immunologists
Journal of Immunology, 184(12), 6600. American Association of Immunologists

Dendritic cells (DCs) are composed of different subsets that exhibit distinct functionality in the induction and regulation of immune responses. The myeloid DC subsets, including interstitial DCs and Langerhans cells (LCs), develop from CD34+ hematop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae906acb94137f6c008142174023c51c
https://doi.org/10.4049/jimmunol.0903089

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