Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Lianne I. Willems"'
Autor:
Nicholas G. S. McGregor, Casper de Boer, Quentin P. O. Foucart, Thomas Beenakker, Wendy A. Offen, Jeroen D. C. Codée, Lianne I. Willems, Herman S. Overkleeft, Gideon J. Davies
Publikováno v:
ACS Central Science, Vol 9, Iss 12, Pp 2306-2314 (2023)
Externí odkaz:
https://doaj.org/article/0ab70068664a46b0b310b3eed566d8f6
Autor:
Laura I. Mazilescu, MD, Peter Urbanellis, MD, MSc, Moritz J. Kaths, MD, MSc, Sujani Ganesh, MSc, Toru Goto, MD, Yuki Noguchi, MD, PhD, Rohan John, MD, Ana Konvalinka, MD, PhD, Istvan Mucsi, MD, PhD, Anand Ghanekar, MD, PhD, Darius J. Bagli, MD, MSc, Julie Turgeon, PhD, Annie Karakeusian Rimbaud, BSc, Marie-Josée Hébert, MD, Mélanie Dieudé, PhD, Isabelle Alleys, PhD, Etienne Dore, MSc, Eric Boilard, PhD, Herman S. Overkleeft, PhD, Lianne I. Willems, PhD, Lisa A. Robinson, MD, Markus Selzner, MD
Publikováno v:
Transplantation Direct, Vol 7, Iss 10, p e751 (2021)
Background. The increased usage of marginal grafts has triggered interest in perfused kidney preservation to minimize graft injury. We used a donation after circulatory death (DCD) porcine kidney autotransplantation model to compare 3 of the most fre
Externí odkaz:
https://doaj.org/article/af252ed324fa4c4ba755708e4549c1cb
Publikováno v:
Molecules, Vol 25, Iss 24, p 5994 (2020)
Activity-based protein profiling (ABPP) is a powerful technique to label and detect active enzyme species within cell lysates, cells, or whole animals. In the last two decades, a wide variety of applications and experimental read-out techniques have
Externí odkaz:
https://doaj.org/article/7b6c301abeb249cb973b45ea33423dd9
Autor:
Lloyd D. Murphy, Kathryn E. Huxley, Ava Wilding, Cyane Robinson, Quentin P. O. Foucart, Lianne I. Willems
Publikováno v:
Chemical Science. 14:5062-5068
The synthesis of phosphotriesters bearing biolabile SATE protecting groups is achieved in two steps from an easy to synthesise tri(bromoalkyl)phosphate precursor. The method provides access to caged phosphorylated sugars and amino acid derivatives.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50cb27c14cdacbb438b7a4a707fc5995
https://doi.org/10.1039/d3sc00693j
https://doi.org/10.1039/d3sc00693j
Autor:
Yanping Zhu, Lianne I. Willems, Leonard J. Foster, Weifeng B. Wu, Daniela Salas, David J. Vocadlo, Samy Cecioni
Publikováno v:
Journal of the American Chemical Society. 142:15729-15739
Hundreds of nuclear, cytoplasmic, and mitochondrial proteins within multicellular eukaryotes have hydroxyl groups of specific serine and threonine residues modified by the monosaccharide N-acetylglucosamine (GlcNAc). This modification, known as O-Glc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b279849ccd60b142bffeb3c695ed1bb
https://doi.org/10.1021/jacs.0c04121
https://doi.org/10.1021/jacs.0c04121
Publikováno v:
Molecules
Molecules, Vol 25, Iss 5994, p 5994 (2020)
Molecules, Vol 25, Iss 5994, p 5994 (2020)
Activity-based protein profiling (ABPP) is a powerful technique to label and detect active enzyme species within cell lysates, cells, or whole animals. In the last two decades, a wide variety of applications and experimental read-out techniques have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a96841890369aa79a450ae8d9f88a80
https://lirias.kuleuven.be/handle/123456789/671254
https://lirias.kuleuven.be/handle/123456789/671254
Autor:
David L. Shen, Matthew G. Alteen, Razieh Eskandari, Hong Yee Tan, Lianne I. Willems, Zarina Madden, Ta-Wei Liu, David J. Vocadlo, Yanping Zhu
The modification of proteins with O-linked N-acetylglucosamine ( O-GlcNAc) by the enzyme O-GlcNAc transferase (OGT) has emerged as an important regulator of cellular physiology. Metabolic labeling strategies to monitor O-GlcNAcylation in cells have p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413bcf1b7ca50411f82dae51eb7769f1
https://eprints.whiterose.ac.uk/138310/1/Tan_JACS_2018_accepted_manuscript.docx
https://eprints.whiterose.ac.uk/138310/1/Tan_JACS_2018_accepted_manuscript.docx
Autor:
Daniela Herrera Moro, Bogdan I. Florea, Timothy M. Cox, Olivier R. Martin, Marri Verhoek, Saskia Scheij, André R. A. Marques, Nee Na Kim, Wouter W. Kallemeijn, Rolf G. Boot, Jessica K. Nelson, Herman S. Overkleeft, Lianne I. Willems, Roelof Ottenhoff, Johannes M. F. G. Aerts, Cindy P. A. A. van Roomen, M. Begoña Cachón-González, Anna Biela-Banas
Publikováno v:
Chembiochem, 18(4), 402-412. Wiley-VCH Verlag
Galactosylceramidase (GALC) is the lysosomal β-galactosidase responsible for the hydrolysis of galactosylceramide. Inherited deficiency in GALC causes Krabbe disease, a devastating neurological disorder characterized by accumulation of galactosylcer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5408323f10bcb551113378d4c12edaaa
https://hdl.handle.net/1887/3199629
https://hdl.handle.net/1887/3199629
Autor:
Benjamin Murray, Herman S. Overkleeft, Johannes M. F. G. Aerts, Hans van den Elst, Jeroen D. C. Codée, Berend Gagestein, Thomas J. M. Beenakker, Gijsbert A. van der Marel, Lianne I. Willems, Wouter W. Kallemeijn, Erwin R. van Rijssel
Publikováno v:
European Journal of Organic Chemistry. 2014:6044-6056
Cyclophellitol and cyclophellitol aziridine are potent and irreversible mechanism-based inhibitors of retaining β-glucosidases. Alterations in the configuration of these compounds can lead to irreversible inhibition of different classes of retaining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ce5e6dde17a21ffd332316d8265b0b1
https://doi.org/10.1002/ejoc.201402589
https://doi.org/10.1002/ejoc.201402589
Publikováno v:
Bioconjugate Chemistry. 25:1181-1191
Activity-based protein profiling (ABPP) has emerged as a powerful strategy to study the activity of enzymes in complex proteomes. The aim of ABPP is to selectively visualize only the active forms of particular enzymes using chemical probes termed act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89553ae7ff8448ee37cfe210e97822a8
https://doi.org/10.1021/bc500208y
https://doi.org/10.1021/bc500208y