Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lianne I. M. Lansink"'
Autor:
Lianne I. M. Lansink, Oliver P. Skinner, Jessica A. Engel, Hyun Jae Lee, Megan S. F. Soon, Cameron G. Williams, Arya SheelaNair, Clara P. S. Pernold, Pawat Laohamonthonkul, Jasmin Akter, Thomas Stoll, Michelle M. Hill, Arthur M. Talman, Andrew Russell, Mara Lawniczak, Xiaoxiao Jia, Brendon Chua, Dovile Anderson, Darren J. Creek, Miles P. Davenport, David S. Khoury, Ashraful Haque
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Maturation rates of malaria parasites within red blood cells (RBCs) can be influenced by host nutrient status and circadian rhythm; whether host inflammatory responses can also influence maturation remains less clear. Here, we observed that
Externí odkaz:
https://doaj.org/article/ad892e1e2d52402895cf3b6d1a593a65
Autor:
Arya SheelaNair, Aleksandra S. Romanczuk, Rosemary A. Aogo, Rohit Nemai Haldar, Lianne I. M. Lansink, Deborah Cromer, Yandira G. Salinas, R. Kiplin Guy, James S. McCarthy, Miles P. Davenport, Ashraful Haque, David S. Khoury
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-10 (2022)
Abstract Background Artemisinin-based combination therapy (ACT) has been a mainstay for malaria prevention and treatment. However, emergence of drug resistance has incentivised development of new drugs. Defining the kinetics with which circulating pa
Externí odkaz:
https://doaj.org/article/3f61cc61389a4e4f8205817745258ad5
Autor:
Jasmin Akter, Clara P. S. Pernold, Mara K. N. Lawniczak, Arthur M. Talman, Thomas Stoll, Andrew Russell, Lianne I. M. Lansink, Michelle M. Hill, David S. Khoury, Pawat Laohamonthonkul, Cameron G. Williams, Arya SheelaNair, Jessica A. Engel, Hyun Jae Lee, Megan S. F. Soon, Miles P. Davenport, Ashraful Haque
Maturation rate of malaria parasites within red blood cells (RBC) can be influenced by host nutrient status or circadian rhythm. Here, we observed in mice that systemic host inflammation, induced by lipopolysaccharide (LPS) conditioning or ongoing ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0ff5233b339509181ddae6993010a4b
https://doi.org/10.1101/2021.08.18.456784
https://doi.org/10.1101/2021.08.18.456784
Autor:
Cameron G. Williams, Ashraful Haque, Sarah A. Teichmann, Valentine Svensson, Megan S. F. Soon, Antiopi Varelias, Hyun Jae Lee, Lianne I. M. Lansink, Stuart D. Olver, Stacey B. Andersen, Joseph E. Powell, Jessica A. Engel, Motoko Koyama, Geoffrey R. Hill, Rachel D. Kuns
Publikováno v:
JCI Insight
Acute gastrointestinal (GI) graft-versus-host disease (GVHD) is a primary determinant of mortality after allogeneic hematopoietic stem cell transplantation (alloSCT). The condition is mediated by alloreactive donor CD4(+) T cells that differentiate i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60bab2552df102ec486d4bb2c21824a7
https://europepmc.org/articles/PMC7406307/
https://europepmc.org/articles/PMC7406307/
Autor:
Cameron G. Williams, Sarah A. Teichmann, Ashraful Haque, Valentine Svensson, Jessica A. Engel, Rachel D. Kuns, Stacey B. Andersen, Megan S. F. Soon, Joseph E. Powell, Antiopi Varelias, Hyun Jae Lee, Geoffrey R. Hill, Lianne I. M. Lansink, Motoko Koyama, Stuart D. Olver
Acute gastrointestinal Graft-versus-Host-Disease (GVHD) is a primary determinant of mortality after allogeneic hematopoietic stem-cell transplantation (alloSCT). It is mediated by alloreactive donor CD4+ T cells that differentiate into pathogenic sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f67b7772e67f3cb8978dc0e1e4e7ad8
https://doi.org/10.1101/2020.03.08.978239
https://doi.org/10.1101/2020.03.08.978239
Autor:
Megan S F, Soon, Hyun Jae, Lee, Jessica A, Engel, Jasmin, Straube, Bryce S, Thomas, Clara P S, Pernold, Lachlan S, Clarke, Pawat, Laohamonthonkul, Rohit N, Haldar, Cameron G, Williams, Lianne I M, Lansink, Marcela L, Moreira, Michael, Bramhall, Lambros T, Koufariotis, Scott, Wood, Xi, Chen, Kylie R, James, Tapio, Lönnberg, Steven W, Lane, Gabrielle T, Belz, Christian R, Engwerda, David S, Khoury, Miles P, Davenport, Valentine, Svensson, Sarah A, Teichmann, Ashraful, Haque
Publikováno v:
Nature immunology. 21(12)
The dynamics of CD4
Autor:
Ashraful Haque, Lachlan S. Clarke, Scott Wood, Kylie R. James, Xi Chen, Jessica A. Engel, Lianne I. M. Lansink, David S. Khoury, Valentine Svensson, Megan S. F. Soon, Pawat Laohamonthonkul, Clara P. S. Pernold, Steven W. Lane, Hyun Jae Lee, Bryce S. Thomas, Tapio Lönnberg, Jasmin Straube, Marcela de Lima Moreira, Gabrielle T. Belz, Rohit N. Haldar, Christian R. Engwerda, Cameron G. Williams, Michael Bramhall, Miles P. Davenport, Lambros T. Koufariotis, Sarah A. Teichmann
Publikováno v:
Nature Immunology
The dynamics of CD4⁺ T cell memory development remain to be examined at genome scale. In malaria-endemic regions, antimalarial chemoprevention protects long after its cessation and associates with effects on CD4⁺ T cells. We applied single-cell R
Autor:
Jasmin Straube, Therese Vu, Leanne Cooper, Richard J D'Andrea, Geoff R. Hill, Megan Bywater, Michael D. Milsom, Sebastien Jacquelin, Shin-Jye Lee, Florian H. Heidel, Lianne I. M. Lansink, Rebecca Austin, Ann Mullally, Joanne Green, Julius Gräsel, Claudia Bruedigam, Steven W. Lane, Nien-Tsu Chen, Gabor Pali, Chung-Wei Lee, Ashraful Haque
Publikováno v:
Leukemia
JAK2V617F is the most common mutation in patients with BCR-ABL negative myeloproliferative neoplasms (MPNs). The eradication of JAK2V617F hematopoietic stem cells (HSCs) is critical for achieving molecular remissions and cure. We investigate the dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3efd61d329ef1221891f3f699ba3515e
https://europepmc.org/articles/PMC9221569/
https://europepmc.org/articles/PMC9221569/
Autor:
Christian R. Engwerda, Arya Sheela Nair, Rebecca Austin, Shannon E. Best, Daniel Fernandez-Ruiz, Lianne I. M. Lansink, Ashraful Haque, Gayle M. Davey, Megan S. F. Soon, Chelsea L. Edwards, William R. Heath, Kate Schroder, Lily Fogg, Geoffrey R. Hill, Steven W. Lane, Jane A. C. Wilson, Ismail Sebina, Urijah N. Liligeto, Andreas Suhrbier, Kylie R. James
Publikováno v:
The Journal of Immunology. 200:1443-1456
Differentiation of CD4+ Th cells is critical for immunity to malaria. Several innate immune signaling pathways have been implicated in the detection of blood-stage Plasmodium parasites, yet their influence over Th cell immunity remains unclear. In th
Autor:
Daniel Fernandez-Ruiz, Megan S. F. Soon, Matthias H. Enders, Anton Cozijnsen, Paul R. Gilson, Nazanin Ghazanfari, Sanne H. Hendriks, Brendan S. Crabb, Vanessa Mollard, Yu Kato, Wei Yi Ng, Tsuneyasu Kaisho, Lauren E. Holz, Claerwen M. Jones, Kylie R. James, Jessica A. Engel, Lei Shong Lau, William R. Heath, Dorothée L. Berthold, Geoffrey I. McFadden, Tania F. de Koning-Ward, Gayle M. Davey, Francis R. Carbone, Alessandro D. Uboldi, Ganchimeg Bayarsaikhan, Ashraful Haque, Christopher J. Tonkin, Lianne I. M. Lansink
Publikováno v:
The Journal of Immunology. 199:4165-4179
We describe an MHC class II (I-Ab)–restricted TCR transgenic mouse line that produces CD4+ T cells specific for Plasmodium species. This line, termed PbT-II, was derived from a CD4+ T cell hybridoma generated to blood-stage Plasmodium berghei ANKA