Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lianne E.M. Vriend"'
Autor:
Mark A. Exley, Anita Giobbie-Hurder, Steven P. Balk, Yo Mizukami, Tetsuro Sasada, Jerome Ritz, Lianne E.M. Vriend, Kenneth LeClair, F. Stephen Hodi, Heather Daley, Glenn Dranoff, Christine Canning, Phillip Friedlander, Wanyong Zeng, David M. Nemer, Nadia Alatrakchi, Simon Yue, Justice Clark
Publikováno v:
Clinical Cancer Research. 23:3510-3519
Purpose: Invariant NKT cells (iNKT) are innate-like CD1d-restricted T cells with immunoregulatory activity in diseases including cancer. iNKT from advanced cancer patients can have reversible defects including IFNγ production, and iNKT IFNγ product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5170861f27183f1776c3afa5c4c4fd46
https://doi.org/10.1158/1078-0432.ccr-16-0600
https://doi.org/10.1158/1078-0432.ccr-16-0600
Publikováno v:
DNA Repair. 50:1-13
Homologous recombination (HR) is an essential, widely conserved mechanism that utilizes a template for accurate repair of DNA breaks. Some early HR models, developed over five decades ago, anticipated single-strand breaks (nicks) as initiating lesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6dc630d6a789fb6f90867e9520d823
Autor:
Przemek M. Krawczyk, Lianne E.M. Vriend, Nathalie van den Tempel, Frederique J. Pieterson, Arlene L. Oei, Nicolaas A. P. Franken, Roland Kanaar, Mike L’Acosta
Publikováno v:
Oncotarget, 8(57), 97490-97503. Impact Journals
Oncotarget, 8(57), 97490-97503. Impact Journals LLC
Oncotarget
Oncotarget, 8(57), 97490-97503. Impact Journals LLC
Oncotarget
// Lianne E.M. Vriend 1, 2, 3, * , Nathalie van den Tempel 4, * , Arlene L. Oei 2, 3, * , Mike L’Acosta 1 , Frederique J. Pieterson 1 , Nicolaas A.P. Franken 2, 3 , Roland Kanaar 4 and Przemek M. Krawczyk 1, 2, 3 1 Department of Medical Biology, Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4f93ed948bf59265694439089e4820
https://doi.org/10.18632/oncotarget.22142
https://doi.org/10.18632/oncotarget.22142
Autor:
Jan W. Verhoeven, Ruben Bosch, Julia von der Lippe, Ron A. Hoebe, Carel H. van Oven, Henk A. van Veen, Emilie C B Desclos, Enzo M. Scutigliani, Barbara Steurer, Lianne E.M. Vriend, Jakub Kochan, Przemek M. Krawczyk, Jurgen A. Marteijn, Meindert Rijpkema, Jan Stap, Irene Stellingwerf, Jacob A. Aten, Matthias van den Belt
Publikováno v:
Nucleic Acids Research, 47(17):e100. Oxford University Press
Nucleic Acids Research
Nucleic acids research, 47(17). Oxford University Press
Nucleic Acids Research
Nucleic acids research, 47(17). Oxford University Press
The majority of the proteins involved in processing of DNA double-strand breaks (DSBs) accumulate at the damage sites. Real-time imaging and analysis of these processes, triggered by the so-called microirradiation using UV lasers or heavy particle be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b02951989bdc93e34ef7a6211b7301
https://pure.eur.nl/en/publications/618b0255-c9ff-4d34-b027-d1ced1f9443b
https://pure.eur.nl/en/publications/618b0255-c9ff-4d34-b027-d1ced1f9443b
Autor:
Nicolaas A. P. Franken, Lukas J.A. Stalpers, Hans M. Rodermond, Roland Kanaar, Anneke M. Westermann, Przemek M. Krawczyk, Lianne E.M. Vriend, Caspar M. van Leeuwen, Rosemarie ten Cate, H. Petra Kok, Johannes Crezee, Arlene L. Oei
Publikováno v:
Oncotarget
Oncotarget, 8(10), 16303-16312. Impact Journals
Oncotarget, 8(10), 16303-16312. Impact Journals LLC
Oncotarget, 8(10), 16303-16312. Impact Journals
Oncotarget, 8(10), 16303-16312. Impact Journals LLC
Cis-diamminedichloroplatinum(II) (cisplatin, cDDP) is an effective chemotherapeutic agent that induces DNA double strand breaks (DSBs), primarily in replicating cells. Generally, such DSBs can be repaired by the classical or backup non-homologous end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::decf1cd30cd4f52abff75603f3a4db8f
http://europepmc.org/articles/PMC5369964
http://europepmc.org/articles/PMC5369964
Autor:
Francesca Cavallo, Maria Jasin, Lianne E.M. Vriend, Chun-Chin Chen, Przemek M. Krawczyk, Fabio Vanoli, Rohit Prakash, Yu Zhang
Publikováno v:
Nucleic Acids Research
Nucleic acids research, 44(11), 5204-5217. Oxford University Press
Nucleic acids research, 44(11), 5204-5217. Oxford University Press
DNA double-strand breaks (DSBs) are known to be powerful inducers of homologous recombination (HR), but single-strand breaks (nicks) have also been shown to trigger HR. Both DSB- and nick-induced HR (nickHR) are exploited in advanced genome-engineeri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600faa1e6b1e372a12fa36f488d5e9a1
http://europepmc.org/articles/PMC4914091
http://europepmc.org/articles/PMC4914091
Autor:
Lianne E.M. Vriend, Przemek M. Krawczyk, Jakub Kochan, Emilie C B Desclos, Haico van Attikum, Luna Meister, Ruben Bosch
Publikováno v:
Nucleic Acids Research, 45(22)
Nucleic acids research, 45(22), 12625-12637. Oxford University Press
Nucleic Acids Research
Nucleic acids research, 45(22), 12625-12637. Oxford University Press
Nucleic Acids Research
Most proteins involved in the DNA double-strand break response (DSBR) accumulate at the damage sites, where they perform functions related to damage signaling, chromatin remodeling and repair. Over the last two decades, studying the accumulation of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc7e67c4b33a9d4e76670d1a2e916cf
https://hdl.handle.net/1887/96076
https://hdl.handle.net/1887/96076
Autor:
Arlene L. Oei, Lianne E.M. Vriend, Johannes Crezee, Przemek M. Krawczyk, Nicolaas A. P. Franken, Michael R. Horsman
Publikováno v:
Oei, A L, Vriend, L E M, Krawczyk, P M, Horsman, M R, Franken, N A P & Crezee, J 2017, ' Targeting therapy-resistant cancer stem cells by hyperthermia ', International Journal of Hyperthermia, vol. 33, no. 4, pp. 419-427 . https://doi.org/10.1080/02656736.2017.1279757
Eradication of all malignant cells is the ultimate but challenging goal of anti-cancer treatment; most traditional clinically-available approaches fail because there are cells in a tumour that either escape therapy or become therapy-resistant. A subp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b2f2fef442f6e44a8b0b7a6f07303f
https://pure.au.dk/portal/da/publications/targeting-therapyresistant-cancer-stem-cells-by-hyperthermia(be62aba9-eba0-45b0-b346-4688549a99de).html
https://pure.au.dk/portal/da/publications/targeting-therapyresistant-cancer-stem-cells-by-hyperthermia(be62aba9-eba0-45b0-b346-4688549a99de).html
Autor:
Renske D.M. Steenbergen, Erik Hooijberg, Marianne Tijssen, Lianne E.M. Vriend, Beatriz Carvalho, Gerrit A. Meijer, Florence L. M. de Groen, Bauke Ylstra, Oscar Krijgsman
Publikováno v:
Genes, Chromosomes and Cancer. 53:339-348
Colorectal cancer (CRC) development is in most cases marked by the accumulation of genomic alterations including gain of the entire q-arm of chromosome 13. This aberration occurs in 40%-60% of all CRC and is associated with progression from adenoma t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee2e8857c7f5500209eef9d71ce3cbfb
https://doi.org/10.1002/gcc.22144
https://doi.org/10.1002/gcc.22144
Publikováno v:
Biochimica et Biophysica Acta. Reviews on Cancer, 1836(2), 227-235. Elsevier
Vriend, L E M, Versélewel de Witt Hamer, P C, van Noorden, C J F & Wurdinger, T 2013, ' WEE1 inhibition and genomic instability in cancer ', Biochimica et Biophysica Acta. Reviews on Cancer, vol. 1836, no. 2, pp. 227-235 . https://doi.org/10.1016/j.bbcan.2013.05.002
Vriend, L E M, Versélewel de Witt Hamer, P C, van Noorden, C J F & Wurdinger, T 2013, ' WEE1 inhibition and genomic instability in cancer ', Biochimica et Biophysica Acta. Reviews on Cancer, vol. 1836, no. 2, pp. 227-235 . https://doi.org/10.1016/j.bbcan.2013.05.002
One of the hallmarks of cancer is genomic instability controlled by cell cycle checkpoints. The G1 and G2 checkpoints allow DNA damage responses, whereas the mitotic checkpoint enables correct seggregation of the sister chromosomes to prevent aneuplo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8ceac91e5a267e55cfde182562745c
https://doi.org/10.1016/j.bbcan.2013.05.002
https://doi.org/10.1016/j.bbcan.2013.05.002