The Drosophila Baramicin polypeptide gene protects against fungal infection.

Autor: Mark Austin Hanson, Lianne B Cohen, Alice Marra, Igor Iatsenko, Steven A Wasserman, Bruno Lemaitre

Publikováno v: PLoS Pathogens, Vol 17, Iss 8, p e1009846 (2021)

The fruit fly Drosophila melanogaster combats microbial infection by producing a battery of effector peptides that are secreted into the haemolymph. Technical difficulties prevented the investigation of these short effector genes until the recent adv

Externí odkaz: https://doaj.org/article/39999117db4448b790680c9f75fec9c9

Expanding the diversity of mycobacteriophages: insights into genome architecture and evolution.

Autor: Welkin H Pope, Deborah Jacobs-Sera, Daniel A Russell, Craig L Peebles, Zein Al-Atrache, Turi A Alcoser, Lisa M Alexander, Matthew B Alfano, Samantha T Alford, Nichols E Amy, Marie D Anderson, Alexander G Anderson, Andrew A S Ang, Manuel Ares, Amanda J Barber, Lucia P Barker, Jonathan M Barrett, William D Barshop, Cynthia M Bauerle, Ian M Bayles, Katherine L Belfield, Aaron A Best, Agustin Borjon, Charles A Bowman, Christine A Boyer, Kevin W Bradley, Victoria A Bradley, Lauren N Broadway, Keshav Budwal, Kayla N Busby, Ian W Campbell, Anne M Campbell, Alyssa Carey, Steven M Caruso, Rebekah D Chew, Chelsea L Cockburn, Lianne B Cohen, Jeffrey M Corajod, Steven G Cresawn, Kimberly R Davis, Lisa Deng, Dee R Denver, Breyon R Dixon, Sahrish Ekram, Sarah C R Elgin, Angela E Engelsen, Belle E V English, Marcella L Erb, Crystal Estrada, Laura Z Filliger, Ann M Findley, Lauren Forbes, Mark H Forsyth, Tyler M Fox, Melissa J Fritz, Roberto Garcia, Zindzi D George, Anne E Georges, Christopher R Gissendanner, Shannon Goff, Rebecca Goldstein, Kobie C Gordon, Russell D Green, Stephanie L Guerra, Krysta R Guiney-Olsen, Bridget G Guiza, Leila Haghighat, Garrett V Hagopian, Catherine J Harmon, Jeremy S Harmson, Grant A Hartzog, Samuel E Harvey, Siping He, Kevin J He, Kaitlin E Healy, Ellen R Higinbotham, Erin N Hildebrandt, Jason H Ho, Gina M Hogan, Victoria G Hohenstein, Nathan A Holz, Vincent J Huang, Ericka L Hufford, Peter M Hynes, Arrykka S Jackson, Erica C Jansen, Jonathan Jarvik, Paul G Jasinto, Tuajuanda C Jordan, Tomas Kasza, Murray A Katelyn, Jessica S Kelsey, Larisa A Kerrigan, Daryl Khaw, Junghee Kim, Justin Z Knutter, Ching-Chung Ko, Gail V Larkin, Jennifer R Laroche, Asma Latif, Kohana D Leuba, Sequoia I Leuba, Lynn O Lewis, Kathryn E Loesser-Casey, Courtney A Long, A Javier Lopez, Nicholas Lowery, Tina Q Lu, Victor Mac, Isaac R Masters, Jazmyn J McCloud, Molly J McDonough, Andrew J Medenbach, Anjali Menon, Rachel Miller, Brandon K Morgan, Patrick C Ng, Elvis Nguyen, Katrina T Nguyen, Emilie T Nguyen, Kaylee M Nicholson, Lindsay A Parnell, Caitlin E Peirce, Allison M Perz, Luke J Peterson, Rachel E Pferdehirt, Seegren V Philip, Kit Pogliano, Joe Pogliano, Tamsen Polley, Erica J Puopolo, Hannah S Rabinowitz, Michael J Resiss, Corwin N Rhyan, Yetta M Robinson, Lauren L Rodriguez, Andrew C Rose, Jeffrey D Rubin, Jessica A Ruby, Margaret S Saha, James W Sandoz, Judith Savitskaya, Dale J Schipper, Christine E Schnitzler, Amanda R Schott, J Bradley Segal, Christopher D Shaffer, Kathryn E Sheldon, Erica M Shepard, Jonathan W Shepardson, Madav K Shroff, Jessica M Simmons, Erika F Simms, Brandy M Simpson, Kathryn M Sinclair, Robert L Sjoholm, Ingrid J Slette, Blaire C Spaulding, Clark L Straub, Joseph Stukey, Trevor Sughrue, Tin-Yun Tang, Lyons M Tatyana, Stephen B Taylor, Barbara J Taylor, Louise M Temple, Jasper V Thompson, Michael P Tokarz, Stephanie E Trapani, Alexander P Troum, Jonathan Tsay, Anthony T Tubbs, Jillian M Walton, Danielle H Wang, Hannah Wang, John R Warner, Emilie G Weisser, Samantha C Wendler, Kathleen A Weston-Hafer, Hilary M Whelan, Kurt E Williamson, Angelica N Willis, Hannah S Wirtshafter, Theresa W Wong, Phillip Wu, Yun jeong Yang, Brandon C Yee, David A Zaidins, Bo Zhang, Melina Y Zúniga, Roger W Hendrix, Graham F Hatfull

Publikováno v: PLoS ONE, Vol 6, Iss 1, p e16329 (2011)

Mycobacteriophages are viruses that infect mycobacterial hosts such as Mycobacterium smegmatis and Mycobacterium tuberculosis. All mycobacteriophages characterized to date are dsDNA tailed phages, and have either siphoviral or myoviral morphotypes. H

Externí odkaz: https://doaj.org/article/a9e00ac52f7f45099a82269efcbad2c5

The Daisho Peptides Mediate Drosophila Defense Against a Subset of Filamentous Fungi

Autor: Lianne B. Cohen, Yangyang Xu, Steven A. Wasserman, Scott A. Lindsay, Samuel J. H. Lin

Publikováno v: Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology

Fungal infections, widespread throughout the world, affect a broad range of life forms, including agriculturally relevant plants, humans, and insects. In defending against fungal infections, the fruit fly Drosophila melanogaster employs the Toll path

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9d64c1ddca2a21d3f0857c286e3391
https://www.frontiersin.org/article/10.3389/fimmu.2020.00009/full

Tethered Fluorogen Assay to Visualize Membrane Apposition in Living Cells

Autor: Jonathan W. Jarvik, Lianne B. Cohen, Kalin V. Vasilev, Daniel S. Ackerman, Brigitte F. Schmidt

Publikováno v: Bioconjugate Chemistry. 28:1356-1362

We describe proof-of-concept for a novel approach for visualizing regions of close apposition between the surfaces of living cells. A membrane-anchored protein with high affinity for a chemical ligand is expressed on the surface of one set of cells,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0426c136460c09e1ecb96c23b6ae0d
https://doi.org/10.1021/acs.bioconjchem.7b00047

The role of the bZIP transcription factor ZIP-1 in the Intracellular Pathogen Response of C. elegans

Autor: Vladimir Lazetic, Fengting Wu, Lianne B Cohen, Kirthi C Reddy, Emily R Troemel

Publikováno v: The Journal of Immunology. 204:70.21-70.21

How does the nematode Caenorhabditis elegans respond to natural pathogen infections with non-professional immune cells? To answer this question, we are studying the Intracellular Pathogen Response (IPR) – a host transcriptional response common to i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2456f5517d08018040a5affb2ca4b33
https://doi.org/10.4049/jimmunol.204.supp.70.21