Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lianjie Wei"'
Autor:
Natalie M. Niemi, Lia R. Serrano, Laura K. Muehlbauer, Catherine E. Balnis, Lianjie Wei, Andrew J. Smith, Keri-Lyn Kozul, Merima Forny, Olivia M. Connor, Edrees H. Rashan, Evgenia Shishkova, Kathryn L. Schueler, Mark P. Keller, Alan D. Attie, Jonathan R. Friedman, Julia K. Pagan, Joshua J. Coon, David J. Pagliarini
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract PPTC7 is a resident mitochondrial phosphatase essential for maintaining proper mitochondrial content and function. Newborn mice lacking Pptc7 exhibit aberrant mitochondrial protein phosphorylation, suffer from a range of metabolic defects, a
Externí odkaz:
https://doaj.org/article/d6347c4096ff4f039a05ff1f1aaf0cd0
Publikováno v:
Journal of Biological Chemistry. 299:104030
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1c50241db7e72305c50fd3f61887d10
https://doi.org/10.1016/j.jbc.2023.104030
https://doi.org/10.1016/j.jbc.2023.104030
Autor:
S.J. Pellock, Lianjie Wei, Andrew P. Cesmat, Matthew R. Redinbo, William G. Walton, Dorothy A. Erie, Bich Ngoc T. Tran, Marissa M. Bivins, Michael C. Snider, Ashutosh Tripathy, Aadra P. Bhatt, Kristen A. Biernat
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Bacterial β-glucuronidase (GUS) enzymes cause drug toxicity by reversing Phase II glucuronidation in the gastrointestinal tract. While many human gut microbial GUS enzymes have been examined with model glucuronide substrates like p-nitrophenol-β-D-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d0a09c0c2f9611457c2fa2554c33f0
http://link.springer.com/article/10.1038/s41598-018-36069-w
http://link.springer.com/article/10.1038/s41598-018-36069-w
Autor:
Alban Ordureau, J. Wade Harper, Michael J. McKenna, Eunyong Park, Sue Im Sim, Lianjie Wei, Sichen Shao
Publikováno v:
Science (New York, N.Y.), vol 369, iss 6511
Science
Science
Dissecting membrane dislocation Mistargeting and misinsertion of membrane proteins causes proteostasis stress and dysfunction of intracellular organelles, which can lead to disease. McKenna et al. found that a conserved orphan P-type adenosine tripho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18eb651a8c8f6125d54a51fee60f0b00
https://doi.org/10.1126/science.abc5809
https://doi.org/10.1126/science.abc5809
Autor:
Lianjie Wei
Gut microbial beta-glucuronidases are one of the key players in reactivating drug metabolites in the gut lumen. This reactivation can sometimes lead to dose-limiting side effects, such as severe diarrhea and intestinal bleeding. Thus, understanding t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::307f0ec418cbbc1d6319cff95110f9fe
