Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Lianhua Qin"'
Autor:
Mengxing Luo, Xin Zou, Qibing Zeng, Yaxing Wu, Hua Yang, Lianhua Qin, Ruijuan Zheng, Fangyou Yu, Yang Hu, Zhonghua Liu
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundAnemia leads to a lower cure rate and poor prognosis in tuberculosis patients. Effective predictors for the prognosis of tuberculosis with anemia (A-TB) are urgently needed. Monocyte has been proven to be a prognostic biomarker of many lung
Externí odkaz:
https://doaj.org/article/1007e3788c88475eb632be715ec0cbe6
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundTuberculosis (TB) is a serious public health problem to human health, but the pathogenesis of TB remains elusive.MethodsTo identify novel candidate genes associated with TB susceptibility, we performed a population-based case control study
Externí odkaz:
https://doaj.org/article/beba06174f3048c68ab35bb3426a4be3
Autor:
Hua Yang, Fei Wang, Xinya Guo, Feng Liu, Zhonghua Liu, Xiangyang Wu, Mengmeng Zhao, Mingtong Ma, Haipeng Liu, Lianhua Qin, Lin Wang, Tianqi Tang, Wei Sha, Yang Wang, Jianxia Chen, Xiaochen Huang, Jie Wang, Cheng Peng, Ruijuan Zheng, Fen Tang, Lu Zhang, Chunyan Wu, Stefan H. Oehlers, Zhigang Song, Jialei She, Hua Feng, Xunwei Xie, Baoxue Ge
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-18 (2021)
Abstract Pathogenic mycobacteria induce the formation of hypoxic granulomas during latent tuberculosis (TB) infection, in which the immune system contains, but fails to eliminate the mycobacteria. Fatty acid metabolism-related genes are relatively ov
Externí odkaz:
https://doaj.org/article/8926a826463b41a297a8323e451cdda6
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Sputum smear microscopy for tuberculosis diagnosis has stood the test of time. However, due to its low sensitivity, the positive detection rate for tuberculosis in clinical specimens is not high. To improve the sensitivity of microscopic obs
Externí odkaz:
https://doaj.org/article/9d8bbe443d4849e7ab0711eb00cb8d60
Autor:
Hua Quan, Wenhong Wu, Guanghong Yang, Yunlin Wu, Wenlan Yang, Chunyan Min, Jinyun Shi, Lianhua Qin, Jin Huang, Jie Wang, Xiaochen Huang, Ling Mao, Yonghong Feng
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundSilicosis poses a threat to workers’ health due to the irreversible lung lesions.DesignA retrospective cohort study.MethodsA total of 259 patients [80 worked with artificial stone (AS), 179 with non-artificial stone (non-AS)] with confirm
Externí odkaz:
https://doaj.org/article/924cdb262b084a2a94d09aad8a6df1f3
Autor:
Lianhua Qin, Jie Wang, Junmei Lu, Hua Yang, Ruijuan Zheng, Zhonghua Liu, Xiaochen Huang, Yonghong Feng, Zhongyi Hu, Baoxue Ge
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-12 (2019)
Abstract Background The emergence of drug-resistant strains of Mycobacterium tuberculosis (Mtb), especially those that are multidrug resistant poses a serious threat to global tuberculosis control. However, the mechanism underlying the occurrence of
Externí odkaz:
https://doaj.org/article/526ce3257ef94d60ac55ce6c96e69909
Autor:
Ruijuan Zheng, Zhiqiang Li, Fusheng He, Haipeng Liu, Jianhua Chen, Jiayu Chen, Xuefeng Xie, Juan Zhou, Hao Chen, Xiangyang Wu, Juehui Wu, Boyu Chen, Yahui Liu, Haiyan Cui, Lin Fan, Wei Sha, Yin Liu, Jiqiang Wang, Xiaochen Huang, Linfeng Zhang, Feifan Xu, Jie Wang, Yonghong Feng, Lianhua Qin, Hua Yang, Zhonghua Liu, Zhenglin Cui, Feng Liu, Xinchun Chen, Shaorong Gao, Silong Sun, Yongyong Shi, Baoxue Ge
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Genetic risk loci for tuberculosis (TB) have so far been identified in African and Russian populations. Here, the authors perform a three-stage GWAS for TB in Han Chinese populations and find two risk loci near ESRRB and TGM6 and further demonstrate
Externí odkaz:
https://doaj.org/article/d25f58a54d96443bbd352c706c5d3f44
Autor:
Wenling Tan, Adiilah K Soodeen-Lalloo, Yue Chu, Weijie Xu, Fengfang Chen, Jie Zhang, Wei Sha, Jin Huang, Guanghong Yang, Lianhua Qin, Jie Wang, Xiaochen Huang, Jingyun Shi, Yonghong Feng
Publikováno v:
Biology of Sex Differences, Vol 9, Iss 1, Pp 1-11 (2018)
Abstract Background Worldwide tuberculosis (TB) reports show a male bias in morbidity; however, the differences in pathogenesis between men and women with TB, as well as the mechanisms associated with such differences, are poorly investigated. We hyp
Externí odkaz:
https://doaj.org/article/67e8a9474a184835b835993c74a93e9f
Autor:
Zhonghua Liu, Yulu Gao, Hua Yang, Haiyang Bao, Lianhua Qin, Changtai Zhu, Yawen Chen, Zhongyi Hu
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166052 (2016)
Mycobacterium tuberculosis (MTB) is a specific aerobic bacterium, but can survive under hypoxic conditions, such as those in lung cheese necrosis, granulomas, or macrophages. It is not clear whether the drug sensitivity and growth characteristics of
Externí odkaz:
https://doaj.org/article/371caadebae540b7a19b6a482b7e47c4
Autor:
Hua Yang, Haizhen Chen, Zhonghua Liu, Hui Ma, Lianhua Qin, Ruiliang Jin, Ruijuan Zheng, Yonghong Feng, Zhenling Cui, Jie Wang, Jinming Liu, Zhongyi Hu
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e52848 (2013)
BACKGROUND: The 10-kDa culture filtrate protein (CFP10) and 6-kDa early-secreted target antigen (ESAT-6) play important roles in mycobacterial virulence and pathogenesis through a 1:1 complex formation (CFP10/ESAT-6 protein, CE protein), which have b
Externí odkaz:
https://doaj.org/article/3921d1f4d7fb474980f36d84d02215bd