Výsledky vyhledávání - "Liangfen Fan"

Data from ERBB3/HER2 Signaling Promotes Resistance to EGFR Blockade in Head and Neck and Colorectal Cancer Models

Autor: Christopher Daly, Gavin Thurston, John S. Rudge, Douglas MacDonald, Gang Chen, Joel H. Martin, Tammy Huang, Ergang Shi, Frank J. Delfino, Jing Shan, Terra B. Potocky, Ashique Rafique, Jeanette L. Fairhurst, Liangfen Fan, Katie Yang, Bo Luan, Carla Castanaro, Li Zhang

EGFR blocking antibodies are approved for the treatment of colorectal cancer and head and neck squamous cell carcinoma (HNSCC). Although ERBB3 signaling has been proposed to limit the effectiveness of EGFR inhibitors, the underlying molecular mechani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b6648e17cc46bf07df9b26c704c96c
https://doi.org/10.1158/1535-7163.c.6536475

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Supplementary Figure 1 from ERBB3/HER2 Signaling Promotes Resistance to EGFR Blockade in Head and Neck and Colorectal Cancer Models

PDF - 78K, Effect of REGN1400 and REGN955 on ligand-induced signaling by ERBB3 and EGFR, respectively.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71092c3804bd3679a5040c51a04f7d1a
https://doi.org/10.1158/1535-7163.22500492

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Supplementary Tables 1 and 2 from ERBB3/HER2 Signaling Promotes Resistance to EGFR Blockade in Head and Neck and Colorectal Cancer Models

PDF - 56K, Measurement of REGN1400 and REGN955 binding affinities.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c1a8712c837e8c8041bfee1e5887b7
https://doi.org/10.1158/1535-7163.22500489.v1

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ERBB3/HER2 Signaling Promotes Resistance to EGFR Blockade in Head and Neck and Colorectal Cancer Models

Autor: Jeanette L. Fairhurst, Christopher Daly, Katie Yang, Gang Chen, Liangfen Fan, Ergang Shi, Carla Castanaro, Joel H. Martin, Ashique Rafique, Douglas MacDonald, Gavin Thurston, Tammy T. Huang, Jing Shan, Bo Luan, John S. Rudge, Li Zhang, Frank Delfino, Terra Potocky

Publikováno v: Molecular Cancer Therapeutics. 13:1345-1355

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a18553166d863f482a80fbe0490ae920
https://doi.org/10.1158/1535-7163.mct-13-1033

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Improved artificial death switches based on caspases and FADD

Autor: Kevin W. Freeman, David M. Spencer, Liangfen Fan, Elizabeth Pham, Tahira Khan

Publikováno v: Human gene therapy. 10(14)

A number of "suicide genes" have been developed as safety switches for gene therapy vectors or as potential inducible cytotoxic agents for hyperproliferative disorders, such as cancer or restenosis. However, most of these approaches have relied on fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d26b6bf5a2425671e09f9112105376
https://pubmed.ncbi.nlm.nih.gov/10515447

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