Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Liangchang Li"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Salidroside (SAL), a phenylpropanoid bioactive compound, has various pharmacological properties, including antioxidant, anti-inflammatory, and hepatoprotective effects. However, the pharmacological effects and mechanisms of action of SAL on cholestat
Externí odkaz:
https://doaj.org/article/06a3f5b996d9409788113dcc38e7cf1c
Autor:
Chang Xu, Yilan Song, Wanting Liu, Ruobai Liu, Qiaoyun Bai, Liangchang Li, Chongyang Wang, Guanghai Yan
Publikováno v:
Redox Biology, Vol 71, Iss , Pp 103090- (2024)
During asthma, there is an intensification of pulmonary epithelial inflammation, mitochondrial oxidative stress, and Golgi apparatus fragmentation. However, the underlying mechanism remains largely unknown. Therefore, this study investigated the role
Externí odkaz:
https://doaj.org/article/bd81099b23a84683ae4f24418b12f7f1
Autor:
Qiaoyun Bai, Ruobai Liu, Changlin Quan, Xue Han, Dandan Wang, Chongyang Wang, Zhiguang Wang, Li Li, Liangchang Li, Hongmei Piao, Yilan Song, Guanghai Yan
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
DEK protein is highly expressed in asthma. However, the mechanism of DEK on mitophagy in asthma has not been fully understood. This study aims to investigate the role and mechanism of DEK in asthmatic airway inflammation and in regulating PINK1-Parki
Externí odkaz:
https://doaj.org/article/ff88ba0ae92144079483dc3b6b9436b7
Autor:
Yilan Song, Jingzhi Jiang, Qiaoyun Bai, Siqi Liu, Yalin Zhang, Chang Xu, Hongmei Piao, Liangchang Li, Guanghai Yan
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Asthma is characterized by chronic inflammation and airway remodeling. However, limited study is conducted on the gene expression profiles of ovalbumin (OVA) induced asthma in mice. Here, we explored the gene expression profiles i
Externí odkaz:
https://doaj.org/article/fdf02e15961347b694c40da73be0b560
Autor:
Hanye Liu, Guanghai Yan, Li Li, Dandan Wang, Yu Wang, Shan Jin, Zhehu Jin, Liangchang Li, Lianhua Zhu
Publikováno v:
BMC Molecular and Cell Biology, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Keloid is a benign proliferative fibrous disease featured by excessive fibroblast proliferation after skin injury. However, the mechanism of abnormal cell proliferation is still unclear. Herein, we investigated the mechanism of ab
Externí odkaz:
https://doaj.org/article/2dc3a587d0dc4426aa368d40011bc166
Autor:
Jiaxu Zhou, Yilan Song, Xingmei Wang, Xinrui Li, Chang Liu, Chenchen Tian, Chongyang Wang, Liangchang Li, Guanghai Yan, Hong Cui
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1444 (2023)
Pulmonary fibrosis may be due to the proliferation of fibroblasts and the aggregation of extracellular matrix, resulting in the stimulation of inflammation damage, destroying lung tissue structure, seriously affecting the patient’s respiratory func
Externí odkaz:
https://doaj.org/article/0ee27674c3db4b478ea9118dfb0895d9
Autor:
Chang Xu, Yilan Song, Zhiguang Wang, Jingzhi Jiang, Yihua Piao, Li Li, Shan Jin, Liangchang Li, Lianhua Zhu, Guanghai Yan
Publikováno v:
Immunity, Inflammation and Disease, Vol 9, Iss 4, Pp 1406-1417 (2021)
Abstract Introduction Pterostilbene (Pts) may be used for allergic asthma treatment. The AMPK/Sirt1 and Nrf2/HO‐1 pathways are potential targets for asthma treatement. However, the relationship between Pts and AMPK/Sirt1 and Nrf2/HO‐1 pathways in
Externí odkaz:
https://doaj.org/article/3feb79822e494617bb2f7bcff4f7c01c
Autor:
Chang Xu, Yilan Song, Chongyang Wang, Jingzhi Jiang, Zhiguang Wang, Liangchang Li, Guanghai Yan
Publikováno v:
Iranian Journal of Allergy, Asthma and Immunology, Vol 21, Iss 5 (2022)
MicroRNAs (miRNAs) can participate in airway remodeling by regulating immune molecule expression. Here, we aimed to identify the differential miRNAs involved in airway remodeling. Airway remodeling was induced by ovalbumin in female BALB/C mice. The
Externí odkaz:
https://doaj.org/article/c2ca7bb2d63e405bb2c9009d0b0e9cf1
Autor:
Zhiguang Wang, Yilan Song, Jingzhi Jiang, Yihua Piao, Li Li, Qiaoyun Bai, Chang Xu, Hanye Liu, Liangchang Li, Hongmei Piao, Guanghai Yan
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Bronchial asthma is characterized by chronic airway inflammation, airway hyperresponsiveness, and airway remodeling. MicroRNA (miRNA) has recently been implicated in the pathogenesis of asthma. However, the mechanisms of different miRNAs in asthma ar
Externí odkaz:
https://doaj.org/article/fd17ea0bcbbb4a1ba221df52928b27d1
Autor:
Hanye Liu, Liangchang Li, Zhengai Chen, Yilan Song, Weidong Liu, Ge Gao, Li Li, Jingzhi Jiang, Chang Xu, Guanghai Yan, Hong Cui
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
This study is to investigate the role of Sphingosine-1-phosphate (S1P) in the asthma progression, and the involvement of autophagy. Airway remodeling mice were subjected to the HE, PAS, and Masson staining. Protein expression levels in the tissues, s
Externí odkaz:
https://doaj.org/article/cc06dab7fb63423d876c1a747be7caa8