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of 3
pro vyhledávání: '"Liang-zhe Wu"'
Autor:
Xiang Zhao, Liang-Zhe Wu, Esther K. Y. Ng, Kerisa W. S. Leow, Qianru Wei, Nicholas R. J. Gascoigne, Joanna Brzostek
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Under physiological conditions, CD8+ T cells need to recognize low numbers of antigenic pMHC class I complexes in the presence of a surplus of non-stimulatory, self pMHC class I on the surface of the APC. Non-stimulatory pMHC have been shown to enhan
Externí odkaz:
https://doaj.org/article/77356d9f19ec4a2eb49a0714187b27e7
Publikováno v:
EMBO reports. 24
T cell activation and effector functions are determined by the affinity of the interaction between T cell receptor (TCR) and its antigenic peptide MHC (pMHC) ligand. A better understanding of the quantitative aspects of TCR-pMHC affinity-dependent T
Autor:
Ling Wu, Joanna Brzostek, Previtha Dawn Sakthi Vale, Qianru Wei, Clara K.T. Koh, June Xu Hui Ong, Liang-zhe Wu, Jia Chi Tan, Yen Leong Chua, Jiawei Yap, Yuan Song, Vivian Jia Yi Tan, Triscilla Y.Y. Tan, Junyun Lai, Paul A. MacAry, Nicholas R.J. Gascoigne
Publikováno v:
Cell Reports Medicine. 4:100917