Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Liang-Yi Hung"'
Autor:
Shiang-Jie Yang, Sheng-Tsung Chang, Kung-Chao Chang, Bo-Wen Lin, Kwang-Yu Chang, Yao-Wen Liu, Ming-Derg Lai, Liang-Yi Hung
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Cancer cells can evade immune elimination by activating immunosuppressive signaling pathways in the tumor microenvironment (TME). Targeting immunosuppressive signaling pathways to promote antitumor immunity has become an attractive strategy
Externí odkaz:
https://doaj.org/article/b94056659c6b490db5774d2e266dbf85
Autor:
Feng-Wei Chen, Yung-Ling Wu, Chao-Chun Cheng, Yu-Wei Hsiao, Jhih-Ying Chi, Liang-Yi Hung, Chih-Peng Chang, Ming-Derg Lai, Ju-Ming Wang
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-19 (2024)
Abstract Background The tumor microenvironment is characterized by inflammation-like and immunosuppression situations. Although cancer-associated fibroblasts (CAFs) are among the major stromal cell types in various solid cancers, including colon canc
Externí odkaz:
https://doaj.org/article/fc78de390566478a976181459c9e7cc0
Autor:
Sina Abdollahi, Seyedeh Zahra Dehghanian, Liang-Yi Hung, Shiang-Jie Yang, Dao-Peng Chen, L. Jeffrey Medeiros, Jung-Hsien Chiang, Kung-Chao Chang
Publikováno v:
Biomarker Research, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Introduction Earlier studies have shown that lymphomatous effusions in patients with diffuse large B-cell lymphoma (DLBCL) are associated with a very poor prognosis, even worse than for non-effusion-associated patients with stage IV disease.
Externí odkaz:
https://doaj.org/article/13e5db784e564a23a23346f7612a53f6
Autor:
Ruo-Yu Chen, Chia-Jui Yen, Yih-Jyh Lin, Ju-Ming Wang, Ting-Fen Tasi, Yu-Chuan Huang, Yao-Wen Liu, Hung-Wen Tsai, Ming-Hao Lee, Liang-Yi Hung
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-13 (2021)
Abstract Chronic and persistent inflammation is a well-known carcinogenesis promoter. Hepatocellular carcinoma (HCC) is one of the most common inflammation-associated cancers; most HCCs arise in the setting of chronic inflammation and hepatic injury.
Externí odkaz:
https://doaj.org/article/b386d754e434499abdb65528261eadb2
Autor:
Kung-Chao Chang, Ruo-Yu Chen, Yu-Chu Wang, Liang-Yi Hung, L. Jeffrey Medeiros, Ya-Ping Chen, Tsai-Yun Chen, Jui-Chu Yang, Po-Min Chiang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract Diffuse large B-cell lymphoma (DLBCL) may present initially in bone marrow, liver and spleen without any lymphadenopathy (referred to as BLS-type DLBCL), which is aggressive and frequently associated with hemophagocytic syndrome. Its tumorig
Externí odkaz:
https://doaj.org/article/68dd808b9c9d4c91a9092e920931f2c1
Autor:
Yu‐Wei Hsiao, Jhih‐Ying Chi, Chien‐Feng Li, Lei‐Yi Chen, Yi‐Ting Chen, Hsin‐Yin Liang, Yu‐Chih Lo, Jhen‐Yi Hong, Chin‐Pin Chuu, Liang‐Yi Hung, Jyun‐Yi Du, Wen‐Chang Chang, Ju‐Ming Wang
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 1, Pp n/a-n/a (2022)
Abstract Due to the heterogeneity and high frequency of genome mutations in cancer cells, targeting vital protumour factors found in stromal cells in the tumour microenvironment may represent an ideal strategy in cancer therapy. However, the regulati
Externí odkaz:
https://doaj.org/article/57e2d11844154b1fb091704d1e6bfcd8
Autor:
Chia-Jui Yen, Shu-Ting Yang, Ruo-Yu Chen, Wenya Huang, Kazuaki Chayama, Ming-Hao Lee, Shiang-Jie Yang, Hong-Sheng Lai, Hsin-Yi Yen, Yu-Wei Hsiao, Ju-Ming Wang, Yih-Jyh Lin, Liang-Yi Hung
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-14 (2019)
Abstract Background Our previous report suggested that centrosomal P4.1-associated protein (CPAP) is required for Hepatitis B virus (HBV) encoded non-structure protein X (HBx)-mediated nuclear factor kappa light chain enhancer of activated B cells (N
Externí odkaz:
https://doaj.org/article/1987785a2d1240ffbec7f6dee6b577ae
Autor:
Hong-Yue Lai, Hsin-Hwa Tsai, Chia-Jui Yen, Liang-Yi Hung, Ching-Chieh Yang, Chung-Han Ho, Hsin-Yin Liang, Feng-Wei Chen, Chien-Feng Li, Ju-Ming Wang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Despite the activation of autophagy may enable residual cancer cells to survive and allow tumor relapse, excessive activation of autophagy may eventually lead to cell death. However, the details of the association of autophagy with primary resistance
Externí odkaz:
https://doaj.org/article/0a73a4e2747b4f3ba9dc6ba24e5a50c8
Autor:
Yu-Chu Wang, Kung-Chao Chang, Bo-Wen Lin, Jenq-Chang Lee, Chien-Hsien Lai, Li-Jyuan Lin, Yun Yen, Chang-Shen Lin, Shiang-Jie Yang, Peng-Chan Lin, Chung-Ta Lee, Liang-Yi Hung
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 6, Pp 1-14 (2018)
Cancer: A regulator of cell cycle gene expression An RNA-binding protein contributes to cancer by boosting the protein-making potential of various genes involved in the cell cycle and cell division. Researchers in Taiwan led by Liang-Yi Hung from the
Externí odkaz:
https://doaj.org/article/63e2601a32054929a16cc5bee24072f1
Autor:
En-Ju Chou, Liang-Yi Hung, Chieh-Ju C. Tang, Wen-Bin Hsu, Hsin-Yi Wu, Pao-Chi Liao, Tang K. Tang
Publikováno v:
Cell Reports, Vol 14, Iss 12, Pp 2975-2987 (2016)
CPAP is required for centriole elongation during S/G2 phase, but the role of CPAP in mitosis is incompletely understood. Here, we show that CPAP maintains spindle pole integrity through its phosphorylation by Aurora-A during mitosis. Depletion of CPA
Externí odkaz:
https://doaj.org/article/1bb22a2249ab43efa6ec85328495d44f