Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Liang-Peng Sun"'
Autor:
Jia Li, Hang Du, Chang-Ji Zheng, Danwen Sun, Hong-Yan Liu, Hu-Ri Piao, Jing-Ya Li, Liang-Peng Sun
Publikováno v:
European Journal of Medicinal Chemistry. 172:163-173
Several series of novel tryptophan-derived rhodanine derivatives were synthesized and identified as potential competitive PTP1B inhibitors and antibacterial agents. Among the compounds studied, 10b was found to have the best in vitro inhibition activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4018792fc37ef36dd8bb727b47e1dd0
https://doi.org/10.1016/j.ejmech.2019.03.059
https://doi.org/10.1016/j.ejmech.2019.03.059
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:1079-1084
Three novel series of dihydrotriazine derivatives bearing 1,3-diaryl pyrazole moieties were designed, synthesized and evaluated in terms of their antibacterial and antifungal activities. Most of the synthesized compounds showed potent inhibition of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48ef4fc8eb8b198f6406e9f10c130a9
https://doi.org/10.1016/j.bmcl.2019.02.033
https://doi.org/10.1016/j.bmcl.2019.02.033
Synthesis and biological evaluation of dihydrotriazine derivatives as potential antibacterial agents
Publikováno v:
Chinese Chemical Letters. 28:1737-1742
A series of 1,4-dihydro-1,3,5-triazine derivatives were designed and synthesized and their antibacterial and antifungal activities were evaluated. Most of the synthesized compounds showed potent inhibition of several Gram-positive bacterial strains (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64ff99733f8af5dabbbc6681f609f9c8
https://doi.org/10.1016/j.cclet.2017.05.022
https://doi.org/10.1016/j.cclet.2017.05.022
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(10)
Two series of 1,3-diphenyl-1H-pyrazole derivatives containing rhodanine-3-alkanoic acid groups were identified as competitive protein tyrosine phosphatase 1B (PTP1B) inhibitors. Among the compounds studied, IIIv was found to have the best in vitro in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52af05541f9fe30130f585af7be53eaa
https://pubmed.ncbi.nlm.nih.gov/30910462
https://pubmed.ncbi.nlm.nih.gov/30910462
Publikováno v:
Bioorganic Chemistry. 106:104483
Two series of 5-aryl-furan derivatives bearing a phenylalanine- or isoleucine-derived rhodanine moiety were identified as competitive protein tyrosine phosphatase 1B (PTP1B) inhibitors. Among the compounds studied, 5g was found to have the best PTP1B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed67bfc94d4cb26078a3c9bc9ba18a6
https://doi.org/10.1016/j.bioorg.2020.104483
https://doi.org/10.1016/j.bioorg.2020.104483
Autor:
Liang-Peng Sun, Ya-Ru Li, Chao Li, Hu-Ri Piao, Jia-Chun Liu, Tian-Yi Zhang, Meng Guo, Chang-Ji Zheng
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:5052-5057
Three series of 1,3-diaryl pyrazole derivatives bearing aminoguanidine or furan-2-carbohydrazide moieties have been synthesized, characterized and evaluated for antibacterial and anti-inflammatory activities. Most of the synthesized compounds showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f401958276ad6d8aa8bc5322321a00
https://doi.org/10.1016/j.bmcl.2015.10.028
https://doi.org/10.1016/j.bmcl.2015.10.028
Autor:
Chang-Ji Zheng, Yan Wu, Yin-Jing Li, Yi Liu, Ming-Xia Song, Hu-Ri Piao, Liang-Peng Sun, Meng Guo
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:4358-4361
Three series of rhodanine derivatives bearing a quinoline moiety (6a-h, 7a-g, and 8a-e) have been synthesized, characterized, and evaluated as antibacterial agents. The majority of these compounds showed potent antibacterial activities against severa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2988b5154e5045caef6dd22d5cc7206b
https://doi.org/10.1016/j.bmcl.2013.05.082
https://doi.org/10.1016/j.bmcl.2013.05.082
Autor:
Ming-Xia Song, Jian Che, Liang-Peng Sun, Yan Wu, Yin-Jing Li, Yi Liu, Chang-Ji Zheng, Hu-Ri Piao, Ya-Jing Bi
Publikováno v:
Medicinal Chemistry Research. 23:426-435
Two series of furan derivatives bearing a rhodanine moiety (4a–l and 5a–l) have been synthesized, characterized, and evaluated for their antibacterial activity. The majority of these compounds showed potent levels of inhibitory activity against a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58efbb0df2956ac2a39ae83998da07ab
https://doi.org/10.1007/s00044-013-0648-7
https://doi.org/10.1007/s00044-013-0648-7
Publikováno v:
Medicinal Chemistry Research. 22:4125-4132
A series of rhodanine-3-acetic acid derivatives were synthesized and investigated for their antibacterial activity against gram-positive bacteria including multidrug-resistant clinical isolates. Among these compounds, 6k with a MIC of 2 μg/mL was as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf2af7738914072b76ccd15ac694fe1c
https://doi.org/10.1007/s00044-012-0417-z
https://doi.org/10.1007/s00044-012-0417-z
Autor:
Zhan-Kui Yu, Hong-Yan Liu, Chang-Ji Zheng, Ke-Qiang Chi, Zhi-Yu Wei, Hu-Ri Piao, Liang-Peng Sun
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(24)
Three novel series of chalcone derivatives containing an aminoguanidine or acylhydrazone moiety were designed, synthesized and evaluated in terms of their antibacterial, antifungal and anti-inflammatory activities. Most of the synthesized compounds s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a3c0405ffaee89181c8a5c5a06beef
https://pubmed.ncbi.nlm.nih.gov/27843112
https://pubmed.ncbi.nlm.nih.gov/27843112