Zobrazeno 1 - 10
of 296
pro vyhledávání: '"Liang OuYang"'
Autor:
Chong-Shuang Pei, Xiao-Ou Hou, Zhen-Yuan Ma, Hai-Yue Tu, Hai-Chun Qian, Yang Li, Kai Li, Chun-Feng Liu, Liang Ouyang, Jun-Yi Liu, Li-Fang Hu
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract Background Autophagy dysfunction in glial cells is implicated in the pathogenesis of Parkinson’s disease (PD). The previous study reported that α-synuclein (α-Syn) disrupted autophagy in cultured microglia. However, the mechanism of micr
Externí odkaz:
https://doaj.org/article/74f57b9ac38040c38a6442c98ac07c8f
Autor:
Fu Peng, Minru Liao, Wenke Jin, Wei Liu, Zixiang Li, Zhichao Fan, Ling Zou, Siwei Chen, Lingjuan Zhu, Qian Zhao, Gu Zhan, Liang Ouyang, Cheng Peng, Bo Han, Jin Zhang, Leilei Fu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Sirtuin 3 (SIRT3) is well known as a conserved nicotinamide adenine dinucleotide+ (NAD+)-dependent deacetylase located in the mitochondria that may regulate oxidative stress, catabolism and ATP production. Accumulating evidence has recently
Externí odkaz:
https://doaj.org/article/0c9da444ccf442e3b3e6e2e182b75a0c
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-45 (2024)
Abstract As the most common form of epigenetic regulation by RNA, N6 methyladenosine (m6A) modification is closely involved in physiological processes, such as growth and development, stem cell renewal and differentiation, and DNA damage response. Me
Externí odkaz:
https://doaj.org/article/1ecab64517f24c6189cf2de766499dc0
Autor:
Jiaxi Liu, Yongya Wu, Sha Meng, Ping Xu, Shutong Li, Yong Li, Xiuying Hu, Liang Ouyang, Guan Wang
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-30 (2024)
Abstract Eukaryotic cells engage in autophagy, an internal process of self-degradation through lysosomes. Autophagy can be classified as selective or non-selective depending on the way it chooses to degrade substrates. During the process of selective
Externí odkaz:
https://doaj.org/article/b8214b8093164ebca1fd0e1fcd3fe999
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 10, Pp 4060-4088 (2023)
Protein–protein interactions (PPIs) are fundamental to many biological processes that play an important role in the occurrence and development of a variety of diseases. Targeting the interaction between tumour-related proteins with emerging small m
Externí odkaz:
https://doaj.org/article/2ab4098f94114f459276258cbbf35a3a
Autor:
Qinwen Zheng, Yumeng Zhu, Aoxue Wang, Panpan Yang, Xin Wang, Wen Shuai, Liang Ouyang, Guan Wang
Publikováno v:
Acta Materia Medica, Vol 2, Iss 4, Pp 377-385 (2023)
Mitogen-activated protein kinases (MAPKs) are a group of serine-threonine protein kinases that can be activated by extracellular stimuli. MAPK14 (p38α) affects major disease processes, while inhibition of p38α has been shown to have potential thera
Externí odkaz:
https://doaj.org/article/80ccbd416aa3490d99958bc7850c9e2a
Autor:
Cailing Gan, Yan Wang, Zhongzheng Xiang, Hongyao Liu, Zui Tan, Yuting Xie, Yuqin Yao, Liang Ouyang, Changyang Gong, Tinghong Ye
Publikováno v:
Journal of Advanced Research, Vol 51, Iss , Pp 109-120 (2023)
Introduction: Idiopathic pulmonary fibrosis (IPF), a life-threatening interstitial lung disease, is characterized by excessive activation and proliferation of fibroblasts and epithelial-mesenchymal transition (EMT) of alveolar epithelial cells (AEC)
Externí odkaz:
https://doaj.org/article/40640b8d9c934be68f51732f444d8e67
Publikováno v:
Energy Storage and Saving, Vol 2, Iss 3, Pp 495-502 (2023)
The dynamic processes and characteristics of solid phase diffusion-bonding of interfacial atoms at high temperatures and the effect of that on bonding strength of Ni (111)/α-Al2O3 (0001) interface were investigated through molecular dynamics. It is
Externí odkaz:
https://doaj.org/article/1b0991be7b934606bb25d2dcc98c6347
Autor:
Shijian Feng, Xiaofang Huang, Dan Tang, Xiaoyu Liu, Liang Ouyang, Dehua Yang, Kunjie Wang, Banghua Liao, Shiqian Qi
Publikováno v:
MedComm, Vol 5, Iss 3, Pp n/a-n/a (2024)
Abstract Ferroptosis is a recently discovered form of regulated cell death characterized by its distinct dependence on iron and the peroxidation of lipids within cellular membranes. Ferroptosis plays a crucial role in physiological and pathological s
Externí odkaz:
https://doaj.org/article/126bd950894f4f48b7cc62b1285a2677
Autor:
Guan Wang, Yongya Wu, Chengyong Wu, Wen Shuai, Tingting Jiang, Aoxue Wang, Faqian Bu, Qiu Sun, Liang Ouyang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 1, Pp 440-443 (2023)
Externí odkaz:
https://doaj.org/article/b066f74405814fe6b8bfa98436c73216