Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Liang Guo Xu"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The virus-induced signaling adaptor protein VISA (also known as MAVS, ISP-1, Cardif) is a critical adaptor protein in the innate immune response to RNA virus infection. Upon viral infection, VISA self-aggregates to form a sizeable prion-like complex
Externí odkaz:
https://doaj.org/article/0b72d4d8feda4085965c992130efb5f7
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT TANK-binding kinase 1 (TBK1)/IκB kinase-ε (IKKε) mediates robust production of type I interferons (IFN-I) and proinflammatory cytokines in response to acute viral infection. However, excessive or prolonged production of IFN-I is harmful a
Externí odkaz:
https://doaj.org/article/19d4b39a662b4247af46c21c7a69312c
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Mitochondrial antiviral signaling protein (MAVS), an adaptor protein, is activated by RIG-I, which is critical for an effective innate immune response to infection by various RNA viruses. Viral infection causes the RIG-I-like receptor (RLR) to recogn
Externí odkaz:
https://doaj.org/article/b66c624c2a144bfebd0e97fdd023aa25
Publikováno v:
Virologica Sinica.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04edf8c6583b80594f35098b03aebd3f
https://doi.org/10.1016/j.virs.2023.04.005
https://doi.org/10.1016/j.virs.2023.04.005
Publikováno v:
Molecular Immunology. 134:62-71
Retinoic acid-inducible gene I (RIG-I) plays a critical role in the recognition of intracytoplasmic viral RNA. Upon binding to the RNA of invading viruses, the activated RIG-I translocates to mitochondria, where it recruits adapter protein MAVS, caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68d3006690d3a4ece793900bc01acfb
https://doi.org/10.1016/j.molimm.2021.03.002
https://doi.org/10.1016/j.molimm.2021.03.002
Autor:
Tian-Sheng He, Tao Xie, Jing Li, Ya-Xian Yang, Changsheng Li, Weiying Wang, Lingzhen Cao, Hua Rao, Cynthia Ju, Liang-Guo Xu
Publikováno v:
Viruses, Vol 11, Iss 2, p 158 (2019)
RNA virus invasion induces a cytosolic RIG-I-like receptor (RLR) signaling pathway by promoting assembly of the Mitochondrial antiviral-signaling protein (MAVS) signalosome and triggers the rapid production of type I interferons (IFNs) and proinflamm
Externí odkaz:
https://doaj.org/article/ed7ef24eeca94fc4b7c8d664128359b8
Autor:
Sheng-Na Li, Dan-Dan Wang, Tian Chen, Ting Ling, Guang-Xiu Weng, Liang-Guo Xu, Wen Hou, Zhi Zhang
Publikováno v:
Molecular Immunology. 132:117-125
Upon recognition of intracytoplasmic viral RNA, activated RIG-I is recruited to the mitochondrion-located adaptor protein VISA (also known as MAVS, CARDIF, and IPS-1). VISA then acts as a central signaling platform for linking RIG-I and downstream si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cc6993e6a2e799d232090011e92928
https://doi.org/10.1016/j.molimm.2021.01.023
https://doi.org/10.1016/j.molimm.2021.01.023
Autor:
Xue Jiang, Liang-Guo Xu
Publikováno v:
Virus genes. 58(2)
Mitochondrial virus-induced signal adaptor (MAVS), also known as VISA, IPS-1, and Cardif, is a crucial adaptor protein in the RIG-I-like receptor (RLR) signaling pathway. Upon viral infection, RIG-I recognizes viral dsRNA and further transfers it to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ec88aac0a116424c470f2f844f7ef8
https://pubmed.ncbi.nlm.nih.gov/35103914
https://pubmed.ncbi.nlm.nih.gov/35103914
Publikováno v:
Journal of Medical Virology. 91:1668-1678
Retinoic acid-inducible gene-I (RIG-I) belongs to the RIGI-like receptors (RLRs), a class of primary pattern recognition receptors. It senses viral double-strand RNA in the cytoplasm and delivers the activated signal to its adaptor virus-induced sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a429dd0e57168bcb41217bf8bab62d0d
https://doi.org/10.1002/jmv.25508
https://doi.org/10.1002/jmv.25508
Autor:
Lingzhen Cao, Tian Chen, Liang-Guo Xu, Changsheng Li, Weiying Wang, Hua Rao, Qing Yang, Tao Xie, Hong-Bing Shu
Publikováno v:
Biochemical and Biophysical Research Communications. 508:667-674
Virus-induced signaling adaptor (VISA), which mediates the production of type I interferon, is crucial for the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) signaling pathway. Upon viral infection, RIG-I recognizes double-stranded viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7472a80fa1cbe95d617e0260b56db309
https://doi.org/10.1016/j.bbrc.2018.11.203
https://doi.org/10.1016/j.bbrc.2018.11.203