Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Liang Chuan Wang"'
Autor:
Cecile Geuijen, Paul Tacken, Liang-Chuan Wang, Rinse Klooster, Pieter Fokko van Loo, Jing Zhou, Arpita Mondal, Yao-bin Liu, Arjen Kramer, Thomas Condamine, Alla Volgina, Linda J. A. Hendriks, Hans van der Maaden, Eric Rovers, Steef Engels, Floris Fransen, Renate den Blanken-Smit, Vanessa Zondag-van der Zande, Abdul Basmeleh, Willem Bartelink, Ashwini Kulkarni, Wilfred Marissen, Cheng-Yen Huang, Leslie Hall, Shane Harvey, Soyeon Kim, Marina Martinez, Shaun O’Brien, Edmund Moon, Steven Albelda, Chrysi Kanellopoulou, Shaun Stewart, Horacio Nastri, Alexander B. H. Bakker, Peggy Scherle, Ton Logtenberg, Gregory Hollis, John de Kruif, Reid Huber, Patrick A. Mayes, Mark Throsby
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
The anti-tumour effect of immune checkpoint inhibitors is potentiated by CD137 agonists in preclinical models, but translation of these results to the clinical practice is hampered by toxicity. Authors describe here a human CD137xPD-L1 bispecific ant
Externí odkaz:
https://doaj.org/article/4044cbbb9c1d4937ac08f857eba69b30
Autor:
Mark Throsby, Arpita Mondal, Kees Bol, Wilfred Marissen, Jeroen Elaissais-Schaap, Paul Tacken, Steef Engels, Liang-Chuan Wang, Alan Roberts, Patrick Mayes, Cecile Geuijen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/fb68b58c8dc743898b32689c799671e6
Autor:
Jing Zhou, Mark Throsby, Lex Bakker, Arpita Mondal, Wilfred Marissen, Paul Tacken, Steef Engels, Liang-Chuan Wang, Patrick Mayes, Cecile Geuijen, Rinse Klooster, Pieter Fokko Van Loo, Yao-Bin Liu, Arjen Kramer, Thomas Condamine, Alla Volgina, Linda Hendriks, Hans van der Maaden, Eric Rovers, Floris Fransen, Renate den Blanken-Smit, Vanessa Zondag-van der Zande, Abdul Basmeleh, Willem Bartelink, Ashwini Kulkarni, Cheng-Yen Huang, Leslie Hall, Shane Harvey, Chrysi Kanellopoulou, Shaun Stewart, Horacio Nastri, Ton Logtenberg, Simon Plyte
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/3ac9962628b4422ba42992da2d11038e
Autor:
Michael C. Milone, Steven Albelda, Ellen Puré, David Barrett, Michael D. Feldman, Timothy Baradet, Albert Lo, Jing Sun, Kheng Newick, Edmund Moon, Zack Gershenson, Vijay Bhoj, Ching-Yi Tsai, Liang-Chuan Wang, Enxiu Wang
CD19-specific KIR-CAR/Dap12 shows antigen-specific cytotoxicity in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1b2dcb3c6784c42ee74838e97e8b53
https://doi.org/10.1158/2326-6066.22538609
https://doi.org/10.1158/2326-6066.22538609
Autor:
Michael C. Milone, Steven Albelda, Ellen Puré, David Barrett, Michael D. Feldman, Timothy Baradet, Albert Lo, Jing Sun, Kheng Newick, Edmund Moon, Zack Gershenson, Vijay Bhoj, Ching-Yi Tsai, Liang-Chuan Wang, Enxiu Wang
Chimeric antigen receptors (CAR) bearing an antigen-binding domain linked in cis to the cytoplasmic domains of CD3ζ and costimulatory receptors have provided a potent method for engineering T-cell cytotoxicity toward B-cell leukemia and lymphoma. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8067d02561e9fbfd36597e9c839d054d
https://doi.org/10.1158/2326-6066.c.6548822.v1
https://doi.org/10.1158/2326-6066.c.6548822.v1
Autor:
Michael C. Milone, Steven Albelda, Ellen Puré, David Barrett, Michael D. Feldman, Timothy Baradet, Albert Lo, Jing Sun, Kheng Newick, Edmund Moon, Zack Gershenson, Vijay Bhoj, Ching-Yi Tsai, Liang-Chuan Wang, Enxiu Wang
SS1-KIRS2 does not affect endogenous TCR expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0531299f4bc9087590547c20d59826f4
https://doi.org/10.1158/2326-6066.22538618
https://doi.org/10.1158/2326-6066.22538618
Autor:
Michael C. Milone, Steven Albelda, Ellen Puré, David Barrett, Michael D. Feldman, Timothy Baradet, Albert Lo, Jing Sun, Kheng Newick, Edmund Moon, Zack Gershenson, Vijay Bhoj, Ching-Yi Tsai, Liang-Chuan Wang, Enxiu Wang
Figure legends for supplemental data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d46e60c2f9840877f47115dc7ae9ec
https://doi.org/10.1158/2326-6066.22538600.v1
https://doi.org/10.1158/2326-6066.22538600.v1
Autor:
Michael C. Milone, Steven Albelda, Ellen Puré, David Barrett, Michael D. Feldman, Timothy Baradet, Albert Lo, Jing Sun, Kheng Newick, Edmund Moon, Zack Gershenson, Vijay Bhoj, Ching-Yi Tsai, Liang-Chuan Wang, Enxiu Wang
SS1-KIRS2/DAP12 T cells mediate robust anti-tumor activity in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b504d29204d6c2f280c7fff0f89e34
https://doi.org/10.1158/2326-6066.22538612.v1
https://doi.org/10.1158/2326-6066.22538612.v1
Autor:
Michael C. Milone, Steven Albelda, Ellen Puré, David Barrett, Michael D. Feldman, Timothy Baradet, Albert Lo, Jing Sun, Kheng Newick, Edmund Moon, Zack Gershenson, Vijay Bhoj, Ching-Yi Tsai, Liang-Chuan Wang, Enxiu Wang
Cytotoxicity induced by SS1-KIRS2, but not receptor expression at the cell surface, depends upon DAP12 co-expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a25e829ead3189da1f1d95012eedd97
https://doi.org/10.1158/2326-6066.22538621
https://doi.org/10.1158/2326-6066.22538621
Autor:
Michael C. Milone, Steven Albelda, Ellen Puré, David Barrett, Michael D. Feldman, Timothy Baradet, Albert Lo, Jing Sun, Kheng Newick, Edmund Moon, Zack Gershenson, Vijay Bhoj, Ching-Yi Tsai, Liang-Chuan Wang, Enxiu Wang
Mesothelin-specific CD3ζ CARs and SS1-KIRS2/Dap12 show comparable antigen-specific in vitro cytotoxicity toward EM-meso cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac433bdd8ec0c7a1c41662d7bd6f5fa9
https://doi.org/10.1158/2326-6066.22538615
https://doi.org/10.1158/2326-6066.22538615