Zobrazeno 1 - 10
of 983
pro vyhledávání: '"Liang‐Nian Ji"'
Publikováno v:
Synthetic and Systems Biotechnology, Vol 4, Iss 3, Pp 113-119 (2019)
α-Pinene is an important monoterpene, which is widely used as a flavoring agent and in fragrances, pharmaceuticals and biofuels. Although an evolved strain Escherichia coli YZFP, which had higher tolerance to pinene and titer, has been successfully
Externí odkaz:
https://doaj.org/article/0bd3e4d782464cb393516b9d68383d07
Publikováno v:
Advanced Science, Vol 7, Iss 1, Pp n/a-n/a (2020)
Abstract Ruthenium complexes are promising photosensitizers (PSs), but their clinical applications have many limitations. Here, a multifunctional nano‐platform PDA‐Pt‐CD@RuFc formed by platinum‐decorated and cyclodextrin (CD)‐modified polyd
Externí odkaz:
https://doaj.org/article/9e927679e7f44fb3919c9f4e0f5ec4e9
Autor:
Johannes Karges, Fangmian Wei, Hui Chao, Ying Zhou, Mingwei Lin, Liang-Nian Ji, Jinchao Shen, Kai Xiong, Yu Chen, Jun-Feng Kou, Ke-Jie Du
Publikováno v:
ACS Applied Materials & Interfaces. 13:38959-38968
Chemotherapy continues to be the most commonly applied strategy for cancer. Despite the impressive clinical success obtained with several drugs, increasing numbers of (multi)drug-resistant tumors are reported. To overcome this shortcoming, novel drug
Autor:
Xiao-Yu Xia, Juan He, Bing Liu, Liang-Nian Ji, Liu-Yi Liu, Hua-Gang Yao, Bo-Chen Zhu, Zong-Wan Mao, Wenting Liu, Bing-Bing Liang
Publikováno v:
Angewandte Chemie. 133:15468-15471
G-quadruplexes (G4s) are prevalent in oncogenes and proposed to be potential antitumor drug targets. However, binding selectivity of compounds to G4s still faces challenges. Herein, we report a platinum(II) complex ( Pt1 ), whose affinity to G4-DNA i
Publikováno v:
Analytical Chemistry. 93:8062-8070
Peroxynitrite (ONOO-) and glutathione (GSH), two unique reactive species, play an essential regulating role in the oxidation and antioxidation in the living body and are closely associated with various physiological and pathological processes, like c
Autor:
Xinlin Lin, Ruilin Guan, Mingwei Lin, Hui Chao, Ying Zhou, Kai Xiong, Yu Chen, Jun-Feng Kou, Liang-Nian Ji
Publikováno v:
Photochemistry and Photobiology. 98:85-91
Four iridium (III) complexes Ir1-Ir4 were synthesized and characterized. Possessing high singlet oxygen production ability and specific mitochondria-localization, Ir1 was developed as a mitochondria-targeting photosensitizer. Ir1 exhibited strong pho
Autor:
Thomas W. Rees, Ruilin Guan, Xinxing Liao, Hui Chao, Liang-Nian Ji, Lina Xie, Kai Xiong, Li-Li Wang, Yu Chen
Publikováno v:
Angewandte Chemie International Edition. 60:4657-4665
Immunogenic cell death (ICD) is a vital component of therapeutically induced anti-tumor immunity. An iridium(III) complex (Ir1), containing an N,N-bis(2-chloroethyl)-azane derivate, as an endoplasmic reticulum-localized ICD inducer for non-small cell
Publikováno v:
Chemical Communications. 57:4408-4411
We developed the first Ru(ii) complex-based bioorthogonal two-photon photosensitizers. Through bioorthogonal labelling, they realize effective tumour-specific photodynamic therapy against triple-negative breast cancer cells.
Publikováno v:
Inorganic Chemistry Frontiers. 8:1788-1794
Necroptosis has emerged as an important mode of programmed cell death (PCD), which can be enhanced by cell cycle arrest. As an alternative destruction mode in cancer therapy, necroptosis induced by chemotherapeutic agents can be a powerful weapon in
Publikováno v:
Chemical Science
Phosphorescent metal complexes are a new kind of multifunctional antitumor compounds that can integrate imaging and antitumor functions in a single molecule. In this minireview, we summarize the recent research progress in this field, concentrating o