Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Liang‐Liang Tang"'
Autor:
Liang-Liang Tang, Xu Yang, Shu-Qi Yu, Qi Qin, Rong Xue, Yu Sun, Han Xiao, An-Qi Shang, Jia-Qun Liu, Song-Qi Han, Chen Liang, Jie Lou, Qiu-Shi Wang, Chang-Jiang Yu, Ming-Ming Wu, Zhi-Ren Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Previous studies have demonstrated that activated endothelial epithelial sodium channel (EnNaC) impairs vasodilatation, which contributes to salt-sensitive hypertension. Here, we investigate whether mesenteric artery (MA) EnNaC is involve
Externí odkaz:
https://doaj.org/article/50b83b65f87e48d3b4da752385de261d
Autor:
Chen Liang, Qiu-Shi Wang, Xu Yang, Di Zhu, Yu Sun, Na Niu, Jie Yao, Bi-Han Dong, Shuai Jiang, Liang-Liang Tang, Jie Lou, Chang-Jiang Yu, Qun Shao, Ming-Ming Wu, Zhi-Ren Zhang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
BackgroundHyperhomocysteinemia (HHcy) causes cardiovascular diseases via regulating inflammatory responses. We investigated whether and how the epithelial sodium channel (ENaC), a recently identified ion channel in endothelial cells, plays a role in
Externí odkaz:
https://doaj.org/article/b3379b58c6a74932ba3112b43f65a8f2
Autor:
Yong-Xu Cai, Bao-Long Zhang, Miao Yu, Yan-Chao Yang, Xue Ao, Di Zhu, Qiu-Shi Wang, Jie Lou, Chen Liang, Liang-Liang Tang, Ming-Ming Wu, Zhi-Ren Zhang, He-Ping Ma
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
We have shown that cholesterol regulates the activity of ion channels in mouse cortical collecting duct (CCD) mpkCCDc14 cells and that the transient receptor potential melastatin 4 (TRPM4) channel is expressed in these cells. However, whether TRPM4 c
Externí odkaz:
https://doaj.org/article/a488d6fafc37435190f74649a7756374
Autor:
Qiu-Shi Wang, Chen Liang, Shuai Jiang, Di Zhu, Yu Sun, Na Niu, Xu Yang, Yan-Chao Yang, Bi-Han Dong, Jie Yao, Chang-Jiang Yu, Jie Lou, Liang-Liang Tang, Ming-Ming Wu, Zhi-Ren Zhang, He-Ping Ma
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The use of cyclosporine A (CsA) in transplant recipients is limited due to its side effects of causing severe hypertension. We have previously shown that CsA increases the activity of the epithelial sodium channel (ENaC) in cultured distal nephron ce
Externí odkaz:
https://doaj.org/article/aa9bcbbf23bd4489a7bc642cfc0eafd9
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Antiangiogenic tyrosine kinases inhibitors induce hypertension, which may increase the incidents of cardiovascular complications and limit their use. However, the mechanisms by which usage of TKIs results in hypertension have not been fully understoo
Externí odkaz:
https://doaj.org/article/dd014d3508f84cdb826ad3a9217a62f6
Autor:
Xiao-Qing Ding, Tao Ban, Zeng-Yan Liu, Jie Lou, Liang-Liang Tang, Jia-Xin Wang, Wen-Feng Chu, Dan Zhao, Bin-Lin Song, Zhi-Ren Zhang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 41, Iss 2, Pp 835-848 (2017)
Background/Aims: The present study investigated whether the transient receptor potential melastatin 4 (TRPM4) channel plays a role in high salt diet (HSD)-induced endothelial injuries. Methods: Western blotting and immunofluorescence were used to exa
Externí odkaz:
https://doaj.org/article/4023d5ab78ed4a7bb7be5dd4c1ec10ad
Autor:
Chang‐Jiang Yu, Liang‐Liang Tang, Chen Liang, Xiao Chen, Shu‐Ying Song, Xiao‐Qing Ding, Kun‐Yu Zhang, Bin‐Lin Song, Dan Zhao, Xue‐Yong Zhu, Hong‐Liang Li, Zhi‐Ren Zhang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 2 (2016)
BackgroundAngiotensin‐converting enzyme 3 (ACE3) is a recently defined homolog of ACE. However, the pathophysiological function of ACE3 is largely unknown. Here, we aim to explore the role of ACE3 in pathological cardiac hypertrophy. Methods and Re
Externí odkaz:
https://doaj.org/article/c4c39db23a9d4c7a884f4290fad394c5
Autor:
Chen, Liang, Di, Zhu, Wei, Xia, Zi, Hong, Qiu-Shi, Wang, Yu, Sun, Yan-Chao, Yang, Song-Qi, Han, Liang-Liang, Tang, Jie, Lou, Ming-Ming, Wu, Zhi-Ren, Zhang
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1869:166586
Lenvatinib, a multitarget tyrosine kinase inhibitor (TKI), increases the incidence of severe hypertension and thus the incidence of cardiovascular complications. Inhibition of ferroptosis, a newly recognized type of cell death, alleviates endothelial
Autor:
Qiu-Shi Wang, Xu Yang, Chen Liang, Di Zhu, Jie Lou, Na Niu, Qun Shao, Liang-Liang Tang, Zhi-Ren Zhang, Shuai Jiang, Bi-Han Dong, Ming-Ming Wu, Jie Yao, Yu Sun, Chang-Jiang Yu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
BackgroundHyperhomocysteinemia (HHcy) causes cardiovascular diseases via regulating inflammatory responses. We investigated whether and how the epithelial sodium channel (ENaC), a recently identified ion channel in endothelial cells, plays a role in
Autor:
Bi-Han Dong, Na Niu, Xu Yang, Jie Yao, Zhi-Ren Zhang, Ming-Ming Wu, Yan-Chao Yang, Di Zhu, Liang-Liang Tang, He-Ping Ma, Chang-Jiang Yu, Yu Sun, Chen Liang, Jie Lou, Shuai Jiang, Qiu-Shi Wang
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology, Vol 12 (2021)
The use of cyclosporine A (CsA) in transplant recipients is limited due to its side effects of causing severe hypertension. We have previously shown that CsA increases the activity of the epithelial sodium channel (ENaC) in cultured distal nephron ce