Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression

Autor: Banerjee, Sourav, Wei, Tiantian, Wang, Jue, Lee, Jenna J., Gutierrez, Haydee L., Chapma, Owen, Wiley, Sandra E., Mayfield, Joshua E., Tandon, Vasudha, Juarez, Edwin F., Chavez, Lukas, Liang, Ruqi, Sah, Robert L., Costello, Caitlin, Mesirov, Jill P., de la Vega, Laureano, Cooper, Kimberly L., Dixon, Jack E., Xiao, Junyu, Lei, Xiaoguang

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2019 Dec 01. 116(49), 24881-24891.

Externí odkaz: https://www.jstor.org/stable/26861688

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Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression

Autor: Jenna J Lee, Haydee L. Gutierrez, Sourav Banerjee, Junyu Xiao, Liang Ruqi, Sandra E. Wiley, Vasudha Tandon, Tiantian Wei, Jue Wang, Kimberly L. Cooper, Lukas Chavez, Edwin F. Juarez, Xiaoguang Lei, Caitlin Costello, Jack E. Dixon, Owen Chapman, Laureano de la Vega, Jill P. Mesirov, Robert L. Sah, Joshua E. Mayfield

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 49
Proceedings of the National Academy of Sciences of the United States of America

Significance Multiple myeloma (MM) and triple-negative breast cancer (TNBC) are dependent on 26S proteasome for malignancy. We have previously shown that the proteasome-regulating kinase DYRK2 is a viable target for both MM and TNBC. Here we identifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7db7d51ffd9e6896fe3714cfa965dda
https://escholarship.org/uc/item/10h2v4tz

MGAT5/TMEM163 variant is associated with prognosis in ursodeoxycholic acid-treated patients with primary biliary cholangitis.

Autor: Wang, Hanxiao, Li, You, Pu, Xiting, Liang, Xueying, Tang, Ruqi, Ma, Xiong

Publikováno v: Journal of Gastroenterology; Jan2024, Vol. 59 Issue 1, p66-74, 9p