Výsledky vyhledávání - "Liane Z. X. Huang"

Akademický článek

Glycosylated extracellular mucin domains protect against SARS-CoV-2 infection at the respiratory surface.

Autor: Maitrayee Chatterjee, Liane Z X Huang, Anna Z Mykytyn, Chunyan Wang, Mart M Lamers, Bart Westendorp, Richard W Wubbolts, Jos P M van Putten, Berend-Jan Bosch, Bart L Haagmans, Karin Strijbis

Publikováno v: PLoS Pathogens, Vol 19, Iss 8, p e1011571 (2023)

Mucins play an essential role in protecting the respiratory tract against microbial infections while also acting as binding sites for bacterial and viral adhesins. The heavily O-glycosylated gel-forming mucins MUC5AC and MUC5B eliminate pathogens by

Externí odkaz: https://doaj.org/article/5c8ab95199664948ba87d8d4e698b857

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions

Autor: Mengying Liu, Liane Z. X. Huang, Anthony A. Smits, Christian Büll, Yoshiki Narimatsu, Frank J. M. van Kuppeveld, Henrik Clausen, Cornelis A. M. de Haan, Erik de Vries

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

It is believed that human Influenza HA glycoprotein attaches to alpha2-6 linked sialic acids (SA) on cells, while avian viruses bind to alpha2-3 linked sialic acids, therewith contributing to host tropism. Here, Liu et al. show that mixing low-affini

Externí odkaz: https://doaj.org/article/5f264ad116df499eba4eda0bda36111d

Zobrazit plný text záznamu