Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Liane Jurida"'
Autor:
Johanna Meier-Soelch, Liane Jurida, Axel Weber, Doris Newel, Johnny Kim, Thomas Braun, M. Lienhard Schmitz, Michael Kracht
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The potent proinflammatory cytokine interleukin (IL)-1 triggers gene expression through the NF-κB signaling pathway. Here, we investigated the cofactor requirements of strongly regulated IL-1 target genes whose expression is impaired in p65 NF-κB-d
Externí odkaz:
https://doaj.org/article/1f677be71ca24920936cc7de11e4258b
Autor:
Liane Jurida, Johanna Soelch, Marek Bartkuhn, Katja Handschick, Helmut Müller, Doris Newel, Axel Weber, Oliver Dittrich-Breiholz, Heike Schneider, Sabin Bhuju, Vera V. Saul, M. Lienhard Schmitz, Michael Kracht
Publikováno v:
Cell Reports, Vol 10, Iss 5, Pp 726-739 (2015)
The inflammatory gene response requires activation of the protein kinase TAK1, but it is currently unknown how TAK1-derived signals coordinate transcriptional programs in the genome. We determined the genome-wide binding of the TAK1-controlled NF-κB
Externí odkaz:
https://doaj.org/article/bbf478becfda4bdf955b0f7f60798020
Autor:
Liane Jurida, Sebastian Werner, Fabienne Knapp, Bernd Niemann, Ling Li, Dimitri Grün, Stefanie Wirth, Axel Weber, Knut Beuerlein, Christoph Liebetrau, Christoph B. Wiedenroth, Stefan Guth, Baktybek Kojonazarov, Leili Jafari, Norbert Weissmann, Stefan Günther, Thomas Braun, Susanne Rohrbach, Michael Kracht
SummaryThe molecular mechanisms of progressive right heart failure are incompletely understood. We systematically compared rat models of pulmonary artery or aortic banding to identify the transcriptomic changes that occur over months in the failing r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79064700f940bfda73382476fce2d27b
https://doi.org/10.1101/2023.05.16.540913
https://doi.org/10.1101/2023.05.16.540913
Autor:
Till Acker, Boyan K. Garvalov, Amparo Acker-Palmer, Michael Kracht, Liane Jurida, Anne-Theres Henze, Angel M. Cuesta, Hui-Ke Jiao, Higinio Dopeso
Lung cancer is the leading cause of cancer-related death worldwide, in large part due to its high propensity to metastasize and to develop therapy resistance. Adaptive responses to hypoxia and epithelial–mesenchymal transition (EMT) are linked to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7485d2a734a8c47e9a3375d24ff9b8f6
https://doi.org/10.1158/0008-5472.c.6510026.v1
https://doi.org/10.1158/0008-5472.c.6510026.v1
Autor:
Till Acker, Boyan K. Garvalov, Amparo Acker-Palmer, Michael Kracht, Liane Jurida, Anne-Theres Henze, Angel M. Cuesta, Hui-Ke Jiao, Higinio Dopeso
Supplementary Figure S1. Epithelial-mesenchymal transition and PHD3 silencing | Supplementary Figure S2. PHD3 silencing promotes EMT through upregulation of TGFα. | Supplementary Figure S3. EGFR signaling and TGFα mediate the effects of PHD3 silenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb37c24a61b09f001e83549bdcccfaf
https://doi.org/10.1158/0008-5472.22418075.v1
https://doi.org/10.1158/0008-5472.22418075.v1
Autor:
Thorsten Stiewe, Michael Kracht, Robert Liefke, Tabea Riedlinger, Andrea Nist, Johanna Meier-Soelch, Liane Jurida, M. Lienhard Schmitz
Publikováno v:
The FASEB Journal
Increasing evidence shows that many transcription factors execute important biologic functions independent from their DNA-binding capacity. The NF-κB p65 (RELA) subunit is a central regulator of innate immunity. Here, we investigated the relative fu
Autor:
Michael Kracht, Knut Beuerlein, Oliver Dittrich-Breiholz, Lilija Brant, Thorsten Stiewe, Helmut Müller, Theodore Georgomanolis, Axel Weber, Tabea Riedlinger, M. Lienhard Schmitz, Wilfred F. J. van IJcken, Argyris Papantonis, Sinah-Sophia Weiterer, Marek Bartkuhn, Ulas Tenekeci, Christin Mayr-Buro, Anna Beyerlein, Hendrik Weiser, Liane Jurida, Johanna Meier-Soelch, Andrea Nist, Athanasia Mizi
Publikováno v:
The EMBO Journal
EMBO Journal, 39(1):e101533. Wiley-Blackwell
EMBO Journal, 39(1):e101533. Wiley-Blackwell
How cytokine‐driven changes in chromatin topology are converted into gene regulatory circuits during inflammation still remains unclear. Here, we show that interleukin (IL)‐1α induces acute and widespread changes in chromatin accessibility via t
Autor:
Ángel M. Cuesta, Amparo Acker-Palmer, Liane Jurida, Boyan K. Garvalov, Anne-Theres Henze, Hui-Ke Jiao, Higinio Dopeso, Michael Kracht, Till Acker
Publikováno v:
Cancer Res.
Lung cancer is the leading cause of cancer-related death worldwide, in large part due to its high propensity to metastasize and to develop therapy resistance. Adaptive responses to hypoxia and epithelial–mesenchymal transition (EMT) are linked to t
Autor:
Marek Bartkuhn, Michael Kracht, Sabin Bhuju, Nadja Karl, Knut Beuerlein, John Ziebuhr, Michael Poppe, Helmut Müller, Liane Jurida, M. Lienhard Schmitz, Sascha Wittig, Jochen Wilhelm
Publikováno v:
PLoS Pathogens, Vol 13, Iss 3, p e1006286 (2017)
PLOS Pathogens
PLoS Pathogens
PLOS Pathogens
PLoS Pathogens
Coronavirus replication takes place in the host cell cytoplasm and triggers inflammatory gene expression by poorly characterized mechanisms. To obtain more insight into the signals and molecular events that coordinate global host responses in the nuc
Autor:
Maren Scharfe, Michael Kracht, Liane Jurida, Knut Beuerlein, Katja Handschick, M. Lienhard Schmitz, Julia Stellzig, Michael Jarek, Marek Bartkuhn, Oliver Dittrich-Breiholz, Axel Weber, Johanna Soelch, Helmut Müller, Heike Schneider
Publikováno v:
Molecular cell. 53(2)
Given the intimate link between inflammation and dysregulated cell proliferation in cancer, we investigated cytokine-triggered gene expression in different cell cycle stages. Transcriptome analysis revealed that G1 release through cyclin-dependent ki