Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Liane Dupont"'
Autor:
Jia Zhe Su, Michael H. Malim, Daniel Cox, Neophytos Kouphou, Sam Acors, Carl Graham, Ana Maria Ortega-Prieto, Luke B Snell, Cassandra Fairhead, Stuart J. D. Neil, Liane Dupont, Helena Winstone, Thomas Lechmere, Rui Pedro Galão, Sadie R. Hallett, Gaia Nebbia, Isabella Huettner, Nathalia Almeida, Marie Jose Lista, Adela Alcolea-Medina, Thomas J. A. Maguire, Suzanne Pickering, Manu Shankar-Hari, Rahul Batra, Jonathan D. Edgeworth, Jose M. Jimenez-Guardeño, Katie J. Doores, Ruth E Dickenson, Jeffrey Seow, Themoula Charalampous, Harry Wilson, Blair Merrick
Publikováno v:
Nature Microbiology
Dupont, L, Snell, L B, Graham, C, Seow, J, Merrick, B, Lechmere, T, Maguire, T J A, Hallett, S R, Pickering, S, Charalampous, T, Alcolea-Medina, A, Huettner, I, Jimenez-Guardeño, J M, Acors, S, Almeida, N, Cox, D, Dickenson, R E, Galao, R P, Kouphou, N, Lista, M J, Ortega-Prieto, A M, Wilson, H, Winstone, H, Fairhead, C, Su, J Z, Nebbia, G, Batra, R, Neil, S, Shankar-Hari, M, Edgeworth, J D, Malim, M H & Doores, K J 2021, ' Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern ', Nature Microbiology, vol. 6, no. 11, pp. 1433-1442 . https://doi.org/10.1038/s41564-021-00974-0
Dupont, L, Snell, L B, Graham, C, Seow, J, Merrick, B, Lechmere, T, Maguire, T J A, Hallett, S R, Pickering, S, Charalampous, T, Alcolea-Medina, A, Huettner, I, Jimenez-Guardeño, J M, Acors, S, Almeida, N, Cox, D, Dickenson, R E, Galao, R P, Kouphou, N, Lista, M J, Ortega-Prieto, A M, Wilson, H, Winstone, H, Fairhead, C, Su, J Z, Nebbia, G, Batra, R, Neil, S, Shankar-Hari, M, Edgeworth, J D, Malim, M H & Doores, K J 2021, ' Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern ', Nature Microbiology, vol. 6, no. 11, pp. 1433-1442 . https://doi.org/10.1038/s41564-021-00974-0
COVID-19 vaccine design and vaccination rollout need to take into account a detailed understanding of antibody durability and cross-neutralizing potential against SARS-CoV-2 and emerging variants of concern (VOCs). Analyses of convalescent sera provi
Autor:
Jennifer Vidler, Shubhankar Sinha, Helen Kakkassery, Jack Cooper, Thanussuyah Alaguthurai, Thomas Hayday, Ana Montes, Yin Wu, Puay Ling Lee, Shraddha Kamdar, Leticia Monin, Muhammad Shamim Khan, Rosalind Graham, Daniel Davies, Maria Conde Poole, Miguel Muñoz-Ruiz, Adam Laing, Charlotte O'Brien-Gore, Sheeba Irshad, Sophie Papa, Anne Rigg, Elizabeth Harvey-Jones, Piers E.M. Patten, Magdalene Joseph, Paul Fields, Clara Domingo-Vila, Mark Harries, Francesca Di Rosa, Jeffrey Seow, Richard Davis, Adrian Hayday, Katie J. Doores, Duncan R. McKenzie, Isaac Francos Quijorna, Josephine Eum, Angela Swampillai, Timothy Tree, Bernard V. North, Liane Dupont, James Spicer, Michael H. Malim, Sultan Abdul-Jawad, Carl Graham, Irene del Molino del Barrio
Publikováno v:
Lancet oncology
22 (2021): 765–778. doi:10.1016/S1470-2045(21)00213-8
info:cnr-pdr/source/autori:Monin, Leticia; Laing, Adam G.; Muñoz-Ruiz, Miguel; McKenzie, Duncan R.; del Molino del Barrio, Irene; Alaguthurai, Thanussuyah; Domingo-Vila, Clara; Hayday, Thomas S.; Graham, Carl; Seow, Jeffrey; Abdul-Jawad, Sultan; Kamdar, Shraddha; Harvey-Jones, Elizabeth; Graham, Rosalind; Cooper, Jack; Khan, Muhammad; Vidler, Jennifer; Kakkassery, Helen; Sinha, Shubhankar; Davis, Richard; Dupont, Liane; Francos Quijorna, Isaac; O'Brien-Gore, Charlotte; Lee, Puay Ling; Eum, Josephine; Conde Poole, Maria; Joseph, Magdalene; Davies, Daniel; Wu, Yin; Swampillai, Angela; North, Bernard V.; Montes, Ana; Harries, Mark; Rigg, Anne; Spicer, James; Malim, Michael H.; Fields, Paul; Patten, Piers; Di Rosa, Francesca; Papa, Sophie; Tree, Timothy; Doores, Katie J.; Hayday, Adrian C.; Irshad, Sheeba/titolo:Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study/doi:10.1016%2FS1470-2045(21)00213-8/rivista:Lancet oncology (Print)/anno:2021/pagina_da:765/pagina_a:778/intervallo_pagine:765–778/volume:22
The Lancet. Oncology
22 (2021): 765–778. doi:10.1016/S1470-2045(21)00213-8
info:cnr-pdr/source/autori:Monin, Leticia; Laing, Adam G.; Muñoz-Ruiz, Miguel; McKenzie, Duncan R.; del Molino del Barrio, Irene; Alaguthurai, Thanussuyah; Domingo-Vila, Clara; Hayday, Thomas S.; Graham, Carl; Seow, Jeffrey; Abdul-Jawad, Sultan; Kamdar, Shraddha; Harvey-Jones, Elizabeth; Graham, Rosalind; Cooper, Jack; Khan, Muhammad; Vidler, Jennifer; Kakkassery, Helen; Sinha, Shubhankar; Davis, Richard; Dupont, Liane; Francos Quijorna, Isaac; O'Brien-Gore, Charlotte; Lee, Puay Ling; Eum, Josephine; Conde Poole, Maria; Joseph, Magdalene; Davies, Daniel; Wu, Yin; Swampillai, Angela; North, Bernard V.; Montes, Ana; Harries, Mark; Rigg, Anne; Spicer, James; Malim, Michael H.; Fields, Paul; Patten, Piers; Di Rosa, Francesca; Papa, Sophie; Tree, Timothy; Doores, Katie J.; Hayday, Adrian C.; Irshad, Sheeba/titolo:Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study/doi:10.1016%2FS1470-2045(21)00213-8/rivista:Lancet oncology (Print)/anno:2021/pagina_da:765/pagina_a:778/intervallo_pagine:765–778/volume:22
The Lancet. Oncology
Summary Background The efficacy and safety profiles of vaccines against SARS-CoV-2 in patients with cancer is unknown. We aimed to assess the safety and immunogenicity of the BNT162b2 (Pfizer–BioNTech) vaccine in patients with cancer. Methods For t
Autor:
Ana Maria Ortega-Prieto, Cassandra Fairhead, Carl Graham, Themoula Charalampous, Harry Wilson, Stuart J. D. Neil, Jose M. Jimenez-Guardeño, Neophytos Kouphou, Thomas Lechmere, Helena Winstone, Rui Pedro Galão, Jeffrey Seow, Michael H. Malim, Isabella Huettner, Ruth E Dickenson, Liane Dupont, Rahul Batra, Jia Su, Marie Jose Lista, Adela Alcolea-Medina, Daniel Cox, Gaia Nebbia, Katie J. Doores, Luke B Snell, Jonathan D. Edgeworth, Manu Shankar-Hari, Nathalia Almeida, Sam Acors, Suzanne Pickering, Blair Merrick, Thomas J. A. Maguire, Sadie R. Hallett
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
As SARS-CoV-2 variants continue to emerge globally, a major challenge for COVID-19 vaccination is the generation of a durable antibody response with cross-neutralizing activity against both current and newly emerging viral variants. Cross-neutralizin
Publikováno v:
The Journal of Biological Chemistry
Human cytomegalovirus (HCMV) latency and reactivation rely on a complex interplay between cellular differentiation, cell signaling pathways, and viral gene functions. HCMV reactivation in dendritic cells (DCs) is triggered by IL-6 and extracellular s
Autor:
Callum Talbot-Cooper, Yongxu Lu, Liane Dupont, Brian J. P. Huntly, Geoffrey L. Smith, Jennifer H. Stuart, Shuchi Agrawal-Singh, Joseph S. Snowden, Andrei I. Smid
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Histone deacetylases (HDACs) are regulators of host gene expression. HDAC4 is shown here to have an important role in type I interferon (IFN) signaling. Here, multiple cell lines lacking HDAC4 had impaired responses to IFN-α and were re
Autor:
Sophie Papa, Thomas Hayday, Carl Graham, Rosalind Graham, Miguel Muñoz-Ruiz, Muhammad Shamim Khan, Maria Conde Poole, Irene del Molino del Barrio, Elizabeth Harvey-Jones, Leticia Monin-Aldama, Francesca Di Rosa, Jeffrey Seow, Puay Lee, Shubhankar Sinha, Katie J. Doores, Helen Kakkassery, Sultan Abdul-Jawad, Anne Rigg, Shraddha Kamdar, Clara Domingo Vila, Sheeba Irshad, Thanussuyah Alaguthurai, Paul Fields, Timothy Tree, Ana Montes, James Spicer, Richard Davis, Jack Cooper, Isaac Francos Quijorna, Liane Dupont, Jennifer Vidler, Michael H. Malim, Piers E.M. Patten, Yin Wu, Magdalene Joseph, Mark Harries, Daniel Davies, Adrian Hayday, Duncan R. McKenzie, Josephine Eum, Adam Laing
BackgroundThe efficacy and safety profile of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have not been definitively established in immunocompromised patient populations. Patients with a known cancer diagnosis were hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f306c775f6a44fc6cb777201f33ee31d
https://doi.org/10.1101/2021.03.17.21253131
https://doi.org/10.1101/2021.03.17.21253131
Autor:
Sergio Martínez Cuesta, Paul J. Lehner, Liane Dupont, Stefan G. Sarafianos, Edward J. D. Greenwood, Ana Teixeira-Silva, Nicholas J Matheson, James C Williamson, Adi Naamati, Stuart Bloor, Raven Shah
Publikováno v:
Cell hostmicrobe. 29(5)
Silencing of nuclear DNA is an essential feature of innate immune responses to invading pathogens. Early in infection, unintegrated lentiviral cDNA accumulates in the nucleus yet remains poorly expressed. In HIV-1-like lentiviruses, the Vpr accessory
Autor:
Laura E. McCoy, Jeffrey Seow, Thomas A. Bowden, Helen M. E. Duyvesteyn, Jose M. Jimenez-Guardeño, Hataf Khan, Neophytos Kouphou, Yuguang Zhao, Marit J. van Gils, Yin Wu, Carl Graham, Peter Cherepanov, Maria Jose Lista, Adam Laing, Manu Shankar-Hari, Liane Dupont, Weng M Ng, Adrian Hayday, Stuart J. D. Neil, Michael H. Malim, Luke Muir, Sam Acors, Annachiara Rosa, Magdalene Joseph, Helena Winstone, Katie J. Doores, Rui Pedro Galão, Isabella Huettner, Suzanne Pickering
Publikováno v:
Immunity, 54(6), 1276-1289.e6. Cell Press
Immunity
Graham, C, Seow, J, Huettner, I, Khan, H, Kouphou, N, Acors, S, Winstone, H, Pickering, S, Galao, R P, Dupont, L, Lista, M J, Jimenez-Guardeño, J M, Laing, A G, Wu, Y, Joseph, M, Muir, L, van Gils, M J, Ng, W M, Duyvesteyn, H M E, Zhao, Y, Bowden, T A, Shankar-Hari, M, Rosa, A, Cherepanov, P, McCoy, L E, Hayday, A C, Neil, S J D, Malim, M H & Doores, K J 2021, ' Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B.1.1.7 variant ', Immunity, vol. 54, no. 6, pp. 1276-1289.e6 . https://doi.org/10.1016/j.immuni.2021.03.023
Immunity
Graham, C, Seow, J, Huettner, I, Khan, H, Kouphou, N, Acors, S, Winstone, H, Pickering, S, Galao, R P, Dupont, L, Lista, M J, Jimenez-Guardeño, J M, Laing, A G, Wu, Y, Joseph, M, Muir, L, van Gils, M J, Ng, W M, Duyvesteyn, H M E, Zhao, Y, Bowden, T A, Shankar-Hari, M, Rosa, A, Cherepanov, P, McCoy, L E, Hayday, A C, Neil, S J D, Malim, M H & Doores, K J 2021, ' Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B.1.1.7 variant ', Immunity, vol. 54, no. 6, pp. 1276-1289.e6 . https://doi.org/10.1016/j.immuni.2021.03.023
Interaction of the SARS-CoV-2 Spike receptor binding domain (RBD) with the receptor ACE2 on host cells is essential for viral entry. RBD is the dominant target for neutralizing antibodies, and several neutralizing epitopes on RBD have been molecularl
Autor:
Liane Dupont, Matthew B. Reeves
Publikováno v:
Reviews in Medical Virology. 26:75-89
Human cytomegalovirus (HCMV) infection remains a major cause of morbidity in patient populations. In certain clinical settings, it is the reactivation of the pre-existing latent infection in the host that poses the health risk. The prevailing view of
Autor:
Liane, Dupont, Matthew B, Reeves
Publikováno v:
Reviews in medical virology. 26(2)
Human cytomegalovirus (HCMV) infection remains a major cause of morbidity in patient populations. In certain clinical settings, it is the reactivation of the pre-existing latent infection in the host that poses the health risk. The prevailing view of