Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Liane Bauersfeld"'
Autor:
Carolin Gerke, Liane Bauersfeld, Ivo Schirmeister, Chiara Noemi-Marie Mireisz, Valerie Oberhardt, Lea Mery, Di Wu, Christopher Sebastian Jürges, Robbert M Spaapen, Claudio Mussolino, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Lars Dölken, Wolfgang Paster, Florian Erhard, Maike Hofmann, Andreas Schlosser, Hartmut Hengel, Frank Momburg, Anne Halenius
Publikováno v:
eLife, Vol 13 (2024)
Human leucocyte antigen class I (HLA-I) molecules play a central role for both NK and T-cell responses that prevent serious human cytomegalovirus (HCMV) disease. To create opportunities for viral spread, several HCMV-encoded immunoevasins employ dive
Externí odkaz:
https://doaj.org/article/c867fd290b5f4af9870c2dc3f63a87b4
Autor:
Cosima Zimmermann, Daniel Kowalewski, Liane Bauersfeld, Andreas Hildenbrand, Carolin Gerke, Magdalena Schwarzmüller, Vu Thuy Khanh Le-Trilling, Stefan Stevanovic, Hartmut Hengel, Frank Momburg, Anne Halenius
Publikováno v:
PLoS Pathogens, Vol 15, Iss 9, p e1008040 (2019)
To escape CD8+ T-cell immunity, human cytomegalovirus (HCMV) US11 redirects MHC-I for rapid ER-associated proteolytic degradation (ERAD). In humans, classical MHC-I molecules are encoded by the highly polymorphic HLA-A, -B and -C gene loci. While HLA
Externí odkaz:
https://doaj.org/article/c911ec06276c49e6a0e23e348cac44c4
Autor:
Carolin Gerke, Liane Bauersfeld, Valerie Oberhardt, Christopher Sebastian Jürges, Robbert M. Spaapen, Claudio Mussolino, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Lars Dölken, Florian Erhard, Maike Hofmann, Hartmut Hengel, Frank Momburg, Anne Halenius
To control human cytomegalovirus (HCMV) infection, NK cells and CD8+T-cells are crucial. HLA class I (HLA-I) molecules play a central role for both NK and T-cell responses and are targets of multifaceted HCMV-encoded immunoevasins. A so far insuffici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::965343521d224702a75eb33f36dd1751
https://doi.org/10.1101/2023.01.10.523457
https://doi.org/10.1101/2023.01.10.523457
Autor:
Janet Kerstin Peper, Annika Nelde, Daniel J. Kowalewski, Hans-Georg Rammensee, Cosima Zimmermann, Maren Lübke, Liane Bauersfeld, Anne Halenius, Oliver Kohlbacher, Juliane S. Walz, Stefanie Spalt, Hartmut Hengel, Stefan Stevanovic, Leon Bichmann, Vu Thuy Khanh Le-Trilling, Ana Marcu
Publikováno v:
The Journal of Experimental Medicine
This work demonstrates a novel strategy that enables the identification of HCMV-derived T cell epitopes by mass spectrometry. It provides a panel of novel T cell epitopes and presents evidence for their involvement in physiologic immune control of HC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48407e835d8675400f41e89c966acfe
https://doi.org/10.1084/jem.20191164
https://doi.org/10.1084/jem.20191164