Zobrazeno 1 - 10
of 325
pro vyhledávání: '"Lianbo, Yu"'
Autor:
Nitin Kumar Pokhrel, Amanda R. Panfil, Haniya Habib, Shamreethaa Seeniraj, Ancy Joseph, Daniel Rauch, Linda Cox, Robert Sprung, Petra Erdmann Gilmore, Qiang Zhang, Robert Reid Townsend, Lianbo Yu, Ayse Selen Yilmaz, Rajeev Aurora, William Park, Lee Ratner, Katherine N. Weilbaecher, Deborah J. Veis
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 10, Pp n/a-n/a (2024)
Abstract Adult T cell leukaemia (ATL), caused by infection with human T‐ lymphotropic virus type 1 (HTLV‐1), is often complicated by hypercalcemia and osteolytic lesions. Therefore, we studied the communication between patient‐derived ATL cells
Externí odkaz:
https://doaj.org/article/d6c03d653e884a26a8afb37f242e9fa2
Autor:
Dionisia Quiroga DO, PhD, Robert Wesolowski MD, Sara Zelinskas BS, Ashley Pinette MD, Brooke Benner PhD, Emily Schwarz BS, Himanshu Savardekar BS, Courtney Johnson DO, Andrew Stiff MD, PhD, Lianbo Yu PhD, Erin Macrae MD, Maryam Lustberg MD, MPH, Ewa Mrozek MD, Bhuvaneswari Ramaswamy MD, William E. Carson MD
Publikováno v:
Cancer Control, Vol 31 (2024)
Objectives CpG ODN is a Toll-like receptor 9 agonist with immunotherapeutic potential for many cancer types, including aggressive breast cancers. There is strong interest in utilizing CpG ODN as an adjuvant to improve clinical efficacy of current tre
Externí odkaz:
https://doaj.org/article/c4a04ac8a9714a0fa31cf6f588fbd325
Autor:
Emily Schwarz, Himanshu Savardekar, Sara Zelinskas, Abigail Mouse, Lianbo Yu, Gregory Behbehani, Timothy Cripe
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 140-141 (2024)
OBJECTIVES/GOALS: IL-12 has potent immune effects but the presence of myeloid-derived suppressor cells (MDSC) can inhibit IL-12-induced NK cell cytotoxicity. Thus, we hypothesized that combining IL-12 with trabectedin, an immunosuppressive myeloid ce
Externí odkaz:
https://doaj.org/article/1bf809a3a56d49bd8f524a7e5b549a3b
Autor:
Kalpana Deepa Priya Dorayappan, Vincent Wagner, Dongju Park, Meghan M. Newcomer, Michelle D. S. Lightfoot, Deepika Kalaiyarasan, Takahiko Sakaue, Wafa Khadraoui, Lianbo Yu, Qi‐En Wang, G. Larry Maxwell, David O'Malley, Raphael E. Pollock, David E. Cohn, Karuppaiyah Selvendiran
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 2, Pp n/a-n/a (2024)
Abstract The interferon stimulated gene 15 (ISG15), a ubiquitin like protein and its conjugates have been implicated in various human malignancies. However, its role in ovarian cancer progression and metastasis is largely unknown. In high grade serou
Externí odkaz:
https://doaj.org/article/f6bfaf655b154822a7ca93373c6a0dd6
Autor:
Shreya Madhav Nuguri, Kevin V. Hackshaw, Silvia de Lamo Castellvi, Yalan Wu, Celeste Matos Gonzalez, Chelsea M. Goetzman, Zachary D. Schultz, Lianbo Yu, Rija Aziz, Michelle M. Osuna-Diaz, Katherine R. Sebastian, W. Michael Brode, Monica M. Giusti, Luis Rodriguez-Saona
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1447 (2024)
Fibromyalgia (FM) is a chronic central sensitivity syndrome characterized by augmented pain processing at diffuse body sites and presents as a multimorbid clinical condition. Long COVID (LC) is a heterogenous clinical syndrome that affects 10–20% o
Externí odkaz:
https://doaj.org/article/6a4aba5d9f1447d9ae10b30d31896f2d
Autor:
Zachary A. Hing, Janek S. Walker, Ethan C. Whipp, Lindsey Brinton, Matthew Cannon, Pu Zhang, Steven Sher, Casey B. Cempre, Fiona Brown, Porsha L. Smith, Claudio Agostinelli, Stefano A. Pileri, Jordan N. Skinner, Katie Williams, Hannah Phillips, Jami Shaffer, Larry P. Beaver, Alexander Pan, Kyle Shin, Charles T. Gregory, Gulcin H. Ozer, Selen A. Yilmaz, Bonnie K. Harrington, Amy M. Lehman, Lianbo Yu, Vincenzo Coppola, Pearlly Yan, Peggy Scherle, Min Wang, Philip Pitis, Chaoyi Xu, Kris Vaddi, Selina Chen-Kiang, Jennifer Woyach, James S. Blachly, Lapo Alinari, Yiping Yang, John C. Byrd, Robert A. Baiocchi, Bradley W. Blaser, Rosa Lapalombella
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Richter’s Transformation is a treatment-resistant and fatal progression from Chronic Lymphocytic Leukemia (CLL) to an aggressive lymphoma. Here, the authors show that PRMT5 is upregulated months prior to and after transformation, PRMT5 overexpressi
Externí odkaz:
https://doaj.org/article/69b4b26dffde485788921c4c7e1fc14a
Autor:
Elizabeth M. Muhowski, Janani Ravikrishnan, Britten Gordon, Lianbo Yu, Shrilekha Misra, Brandi Walker, Sudharshan Eathiraj, Deepa Sampath, Kerry A. Rogers, John C. Byrd, Jennifer A. Woyach
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-5 (2022)
Abstract Inhibitors of B cell receptor (BCR) signaling such as the Bruton’s tyrosine kinase (BTK) inhibitors are effective therapeutics for chronic lymphocytic leukemia (CLL). The first-in-class covalent BTK inhibitor, ibrutinib, produces durable r
Externí odkaz:
https://doaj.org/article/cbd3349984cb4091abe926011ab6ccf0
Autor:
Shreya Madhav Nuguri, Kevin V. Hackshaw, Silvia de Lamo Castellvi, Haona Bao, Siyu Yao, Rija Aziz, Scott Selinger, Zhanna Mikulik, Lianbo Yu, Michelle M. Osuna-Diaz, Katherine R. Sebastian, M. Monica Giusti, Luis Rodriguez-Saona
Publikováno v:
Molecules, Vol 29, Iss 2, p 413 (2024)
The diagnostic criteria for fibromyalgia (FM) have relied heavily on subjective reports of experienced symptoms coupled with examination-based evidence of diffuse tenderness due to the lack of reliable biomarkers. Rheumatic disorders that are common
Externí odkaz:
https://doaj.org/article/e4fd18a6bb8841609c3eccb50d13ec16
Early Diagnosis of Fibromyalgia Using Surface-Enhanced Raman Spectroscopy Combined with Chemometrics
Autor:
Haona Bao, Kevin V. Hackshaw, Silvia de Lamo Castellvi, Yalan Wu, Celeste Matos Gonzalez, Shreya Madhav Nuguri, Siyu Yao, Chelsea M. Goetzman, Zachary D. Schultz, Lianbo Yu, Rija Aziz, Michelle M. Osuna-Diaz, Katherine R. Sebastian, Monica M. Giusti, Luis Rodriguez-Saona
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 133 (2024)
Fibromyalgia (FM) is a chronic muscle pain disorder that shares several clinical features with other related rheumatologic disorders. This study investigates the feasibility of using surface-enhanced Raman spectroscopy (SERS) with gold nanoparticles
Externí odkaz:
https://doaj.org/article/60f59960932449c09918e3682586c3a9
Autor:
Victoria Maksimova, Tasha Wilkie, Susan Smith, Cameron Phelps, Corrine Melvin, Lianbo Yu, Stefan Niewiesk, Patrick L Green, Amanda R Panfil
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011459 (2023)
Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic cause of adult T-cell leukemia/lymphoma (ATL) and encodes a viral oncoprotein (Hbz) that is consistently expressed in asymptomatic carriers and ATL patients, suggesting its importance in th
Externí odkaz:
https://doaj.org/article/25ebcbd7378647a485eec6633cff49d4