Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Liana Zhang"'
Autor:
Laura Brunner, Liana Zhang, Ramak Pourvasei, Mark Ma, Theingi M. Thway, Chris Macaraeg, Michael Eschenberg, Binodh DeSilva, Dominador Calamba
Publikováno v:
Bioanalysis. 2:1587-1596
Background: Incurred sample reanalysis (ISR) is the most recent in-study validation parameter that regulatory agencies have mandated to ensure reproducibility of bioanalytical methods supporting pharmacokinetic/toxicokinetic and clinical studies. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3cc0f1f8912df3d7b99cd5ee503db33
https://doi.org/10.4155/bio.10.75
https://doi.org/10.4155/bio.10.75
Autor:
Michael Hall, Hsieng Sen Lu, Christopher S. Spahr, Robert Ortiz, Steven Yu, Colin V. Gegg, Kenneth W. Walker, Jean W. Lee, Vimal Patel, Liana Zhang, Binodh DeSilva
Publikováno v:
The AAPS Journal. 12:576-585
The knowledge of in vivo biotransformation (e.g., proteolysis) of protein therapeutic candidates reveals structural liabilities that impact stability. This information aids the development and confirmation of ligand-binding assays with the required s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180ca94a2bdcef05a7dfaace19bdf26c
https://doi.org/10.1208/s12248-010-9218-9
https://doi.org/10.1208/s12248-010-9218-9
Autor:
Deanna Mohn, George Doellgast, Kameswara Rao V. Kuchimanchi, Tom Horan, Gerald Siu, Mark E. Dalphin, Frederick W. Jacobsen, Michelle Horner, Helen Kim, Wenyan D. Shen, Daniela Metz, Liana Zhang, Rohini Deshpande, Ming Zhang, James B. Chung, Adimoolam Narayanan
Publikováno v:
European Journal of Pharmacology. 610:110-118
The ICOS (Inducible T cell Co-Stimulator)/B7RP-1 (B7-related protein 1) interaction is critical for the proper activation of a T lymphocyte. In this manuscript we describe a systematic in vivo approach to determine the level of blockade required to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1211ea9af5416b36a6220acaed38d62d
https://doi.org/10.1016/j.ejphar.2009.03.023
https://doi.org/10.1016/j.ejphar.2009.03.023
Publikováno v:
Bioanalysis. 6(19)
Background: A microfluidic platform-based assay was validated to measure a humanized or fully human IgG in rat serum samples. Materials & methods: The cumulative assessment for accuracy and precision was performed with three accuracy and precision ru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e6a5319070926cd0a7f468a6083e54
https://pubmed.ncbi.nlm.nih.gov/25411705
https://pubmed.ncbi.nlm.nih.gov/25411705