Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Liana C. Boraas"'
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195588 (2018)
Use of stem cell-based therapies in tissue engineering and regenerative medicine is hindered by efficient means of directed differentiation. For pluripotent stem cells, an initial critical differentiation event is specification to one of three germ l
Externí odkaz:
https://doaj.org/article/d09a3a9b6e91487ca100b96b90fe4a69
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145084 (2016)
Many emerging cell-based therapies are based on pluripotent stem cells, though complete understanding of the properties of these cells is lacking. In these cells, much is still unknown about the cytoskeletal network, which governs the mechanoresponse
Externí odkaz:
https://doaj.org/article/ed27510c89db43f28b4bb1f4fc5efeb6
Autor:
Liana C. Boraas, Christine Mayr, Gang Zhen, Mengwei Hu, Lauren Thornton, Charles E. Vejnar, Stefania Nicoli, Siyuan Wang, Antonio J. Giraldez
Messenger RNA (mRNA) compartmentalization within the cytosol is well-recognized as a key mechanism of local translation-mediated regulation of protein levels, but whether such localization could be a means of exercising non-coding mRNA function is un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93df514b925f94a14a7708c1d965d995
https://doi.org/10.1101/2021.10.04.463097
https://doi.org/10.1101/2021.10.04.463097
Autor:
Charlene Jouy, Stefania Nicoli, Mengting Gu, Sang Joon Ahn, Liana C. Boraas, William Armero, Tristan P. Driscoll, Albertomaria Moro, Martin A. Schwartz, Joe Swift, Venkatesh Mallikarjun, Mark Gerstein, Jing Zhang, Dong-Hoon Lee, Dionna M. Kasper, Nicolas Baeyens
Publikováno v:
Nature cell biology, 21 (3
Schwartz, M, Moro, A, Driscoll, T, Amero, W, Borass, L, Kaspar, D, Baeyens, N, Jouy, C, Mallikarjun, V, Swift, J, Ahn, S J, Lee, D, Zhang, J, Gu, M, Gerstein, M & Nicoli, S 2019, ' microRNA-dependent regulation of biomechanical genes establishes tissue stiffness homeostasis ', Nature Cell Biology, vol. 21, no. 3, NCB-N34535E, pp. 348-358 . https://doi.org/10.1038/s41556-019-0272-y
Schwartz, M, Moro, A, Driscoll, T, Amero, W, Borass, L, Kaspar, D, Baeyens, N, Jouy, C, Mallikarjun, V, Swift, J, Ahn, S J, Lee, D, Zhang, J, Gu, M, Gerstein, M & Nicoli, S 2019, ' microRNA-dependent regulation of biomechanical genes establishes tissue stiffness homeostasis ', Nature Cell Biology, vol. 21, no. 3, NCB-N34535E, pp. 348-358 . https://doi.org/10.1038/s41556-019-0272-y
Vertebrate tissues exhibit mechanical homeostasis, showing stable stiffness and tension over time and recovery after changes in mechanical stress. However, the regulatory pathways that mediate these effects are unknown. A comprehensive identification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65002f4b74794f049338dd0ef4ad140
https://doi.org/10.1101/359521
https://doi.org/10.1101/359521
Publikováno v:
Tissue Engineering Part A. 19:1564-1572
Corneal disease is the fourth leading cause of blindness. According to the World Health Organization, roughly 1.6 million people globally are blind as a result of this disease. The only current treatment for corneal opacity is a corneal tissue transp
Autor:
Tabassum Ahsan, Liana C. Boraas
Publikováno v:
Scientific Reports
The cytoskeletal filament vimentin is inherent to the endothelial phenotype and is critical for the proper function of endothelial cells in adult mice. It is unclear, however, if the presence of vimentin is necessary during differentiation to the end
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 1, p e0145084 (2016)
PLoS ONE, Vol 11, Iss 1, p e0145084 (2016)
Many emerging cell-based therapies are based on pluripotent stem cells, though complete understanding of the properties of these cells is lacking. In these cells, much is still unknown about the cytoskeletal network, which governs the mechanoresponse