Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Liana C, Chan"'
Autor:
Rajesh Parmar, Harry Pickering, Richard Ahn, Maura Rossetti, David W. Gjertson, Felicia Ruffin, Liana C. Chan, Vance G. Fowler, Michael R. Yeaman, Elaine F. Reed, MRSA Systems Immunology Group, Arnold S. Bayer, Yu-Ling Chang, Scott G. Filler, Vance G. Fowler Jr., David Gjertson, Alexander Hoffmann, Felix Mba Medie, Tsuyoshi Mikkaichi, Simon Mitchell, Yan Qin, Batu K. Sharma-Kuinkel, Katherine Sheu, Joshua Thaden, Alan J. Waring, Yan Q. Xiong, Ying Zheng, Michael R. Yeaman.
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionStaphylococcus aureus bacteremia (SAB) is a life-threatening infection particularly involving methicillin-resistant S. aureus (MRSA). In contrast to resolving MRSA bacteremia (RB), persistent MRSA bacteremia (PB) blood cultures remain pos
Externí odkaz:
https://doaj.org/article/a79666f3f3d748269414ccca0d43d820
Autor:
Tania Wong Fok Lung, Liana C. Chan, Alice Prince, Michael R. Yeaman, Nathan K. Archer, M. Javad Aman, Richard A. Proctor
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Despite meritorious attempts, a S. aureus vaccine that prevents infection or mitigates severity has not yet achieved efficacy endpoints in prospective, randomized clinical trials. This experience underscores the complexity of host-S. aureus interacti
Externí odkaz:
https://doaj.org/article/bc573c1aa8194125a8ccfdafc9362db9
Autor:
Liana C. Chan, Hong K. Lee, Ling Wang, Siyang Chaili, Yan Q. Xiong, Arnold S. Bayer, Richard A. Proctor, Michael R. Yeaman
Publikováno v:
Antibiotics, Vol 12, Iss 7, p 1180 (2023)
Invasive methicillin-resistant Staphylococcus aureus (MRSA) infections are leading causes of morbidity and mortality that are complicated by increasing resistance to conventional antibiotics. Thus, minimizing virulence and enhancing antibiotic effica
Externí odkaz:
https://doaj.org/article/a160510e6a7142b3a32dd3f156556b75
Autor:
Liana C. Chan, Mihyun Park, Hong K. Lee, Siyang Chaili, Yan Q. Xiong, Arnold S. Bayer, Richard A. Proctor, Michael R. Yeaman
Publikováno v:
Antibiotics, Vol 12, Iss 5, p 902 (2023)
Virulence factor expression is integral to pathogenicity of Staphylococcus aureus. We previously demonstrated that aspirin, through its major metabolite, salicylic acid (SAL), modulates S. aureus virulence phenotypes in vitro and in vivo. We compared
Externí odkaz:
https://doaj.org/article/ede63f54fb7e4dcaac5bc879970620ab
Publikováno v:
Trends in Immunology. 44:329-332
Autor:
Selvi C. Ersoy, Liana C. Chan, Michael R. Yeaman, Henry F. Chambers, Richard A. Proctor, Kevin C. Ludwig, Tanja Schneider, Adhar C. Manna, Ambrose Cheung, Arnold S. Bayer
Publikováno v:
Antibiotics, Vol 11, Iss 4, p 462 (2022)
Methicillin-resistant Staphylococcus aureus (MRSA) regulates resistance to β-lactams via preferential production of an alternative penicillin-binding protein (PBP), PBP2a. PBP2a binds many β-lactam antibiotics with less affinity than PBPs which are
Externí odkaz:
https://doaj.org/article/329a3c32a6454aac89e76ce5f344b0ce
Publikováno v:
Antibiotics, Vol 10, Iss 4, p 404 (2021)
Streptococcus mitis-oralis (S. mitis-oralis) infections are increasingly prevalent in specific populations, including neutropenic cancer and endocarditis patients. S. mitis-oralis strains have a propensity to evolve rapid, high-level and durable resi
Externí odkaz:
https://doaj.org/article/5eded07947a346d7a3c14ddce8136b13
Autor:
Mateo Pellegrini, Liana C. Chan, Colin Farrell, Scott G. Filler, Hong Lee, Vance G. Fowler, Elaine F. Reed, Michael R. Yeaman
Publikováno v:
Journal of Clinical and Translational Science, Vol 5, Pp 17-17 (2021)
ABSTRACT IMPACT: This work may provide new targets for vaccine and immunotherapeutic development against MRSA infections. OBJECTIVES/GOALS: Staphylococcus aureus is the leading cause of skin and skin structure infection (SSSI), a primary portal of en
Externí odkaz:
https://doaj.org/article/e5a00d6066374bd880fd9c7e55ab938e
Autor:
Thiago Fauerharmel-Nunes, Ronald S. Flannagan, Mariya I. Goncheva, Arnold S. Bayer, Vance G. Fowler, Liana C. Chan, Michael R. Yeaman, Yan Q. Xiong, David E. Heinrichs
Publikováno v:
Infect Immun
Staphylococcus aureus (especially methicillin-resistant S. aureus [MRSA]) is frequently associated with persistent bacteremia (PB) during vancomycin therapy despite consistent susceptibility in vitro. Strategic comparisons of PB strains versus those
Autor:
Alexander L Greninger, Som S Chatterjee, Liana C Chan, Stephanie M Hamilton, Henry F Chambers, Charles Y Chiu
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149541 (2016)
Fifth-generation cephalosporins, ceftobiprole and ceftaroline, are promising drugs for treatment of bacterial infections from methicillin-resistant Staphylococcus aureus (MRSA). These antibiotics are able to bind native PBP2a, the penicillin-binding
Externí odkaz:
https://doaj.org/article/546280846f3141b3bc0985091616d8b2