Macrophages and brown adipocytes cross-communicate to modulate a thermogenic program following methamphetamine exposure

Autor: Manuel Sanchez-Alavez, Nikki Bortell, Liana Basova, Fahumiya Samad, Maria Cecilia Garibaldi Marcondes

Publikováno v: International Journal of Hyperthermia, Vol 37, Iss 1, Pp 1368-1382 (2020)

Hyperthermia is a potentially lethal side-effect of Methamphetamine (Meth), a stimulant drug. Activation of non-shivering thermogenesis in brown adipose tissue (BAT) is partly responsible for Meth-induced rise in temperature, with contributing sympat

Externí odkaz: https://doaj.org/article/a74782fc95aa4250a61ead48ec046106

FGF Gradient Controls Boundary Position Between Proliferating and Differentiating Cells and Regulates Lacrimal Gland Growth Dynamics

Autor: Suharika Thotakura, Liana Basova, Helen P. Makarenkova

Publikováno v: Frontiers in Genetics, Vol 10 (2019)

Fibroblast growth factor (FGF) signaling plays an important role in controlling cell proliferation, survival, and cell movements during branching morphogenesis of many organs. In mammals branching morphogenesis is primarily regulated by members of th

Externí odkaz: https://doaj.org/article/237d4ab7a31c4906aa59902d1783f2af

Detection of H3K4me3 Identifies NeuroHIV Signatures, Genomic Effects of Methamphetamine and Addiction Pathways in Postmortem HIV+ Brain Specimens that Are Not Amenable to Transcriptome Analysis

Autor: Liana Basova, Alexander Lindsey, Anne Marie McGovern, Ronald J. Ellis, Maria Cecilia Garibaldi Marcondes

Publikováno v: Viruses, Vol 13, Iss 4, p 544 (2021)

Human postmortem specimens are extremely valuable resources for investigating translational hypotheses. Tissue repositories collect clinically assessed specimens from people with and without HIV, including age, viral load, treatments, substance use p

Externí odkaz: https://doaj.org/article/443679d0e277407e8af8e18cff0df341

A mesenchymal to epithelial switch in Fgf10 expression specifies an evolutionary-conserved population of ionocytes in salivary glands

Autor: Olivier Mauduit, Marit H. Aure, Vanessa Delcroix, Liana Basova, Amrita Srivastava, Takeshi Umazume, Jacqueline W. Mays, Saverio Bellusci, Abigail S. Tucker, Mohammad K. Hajihosseini, Matthew P. Hoffman, Helen P. Makarenkova

Publikováno v: Mauduit, O, Aure, M H, Delcroix, V, Basova, L, Srivastava, A, Umazume, T, Mays, J W, Bellusci, S, Tucker, A S, Hajihosseini, M K, Hoffman, M P & Makarenkova, H P 2022, ' A mesenchymal to epithelial switch in Fgf10 expression specifies an evolutionary-conserved population of ionocytes in salivary glands ', Cell Reports, vol. 39, no. 2, 110663 . https://doi.org/10.1016/j.celrep.2022.110663

Fibroblast growth factor 10 (FGF10) is well established as a mesenchyme-derived growth factor and a critical regulator of fetal organ development in mice and humans. Using a single-cell RNA sequencing (RNA-seq) atlas of salivary gland (SG) and a tamo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cf06affc481e13a669239612971e67
https://ueaeprints.uea.ac.uk/id/eprint/84699/

Systems Biology Analysis of the Antagonizing Effects of HIV-1 Tat Expression in the Brain over Transcriptional Changes Caused by Methamphetamine Sensitization

Autor: Maria Cecilia Garibaldi Marcondes, Marcus Kaul, Svetlana Semenova, James P. Kesby, Liana Basova

Publikováno v: Viruses
Viruses, Vol 12, Iss 426, p 426 (2020)
Volume 12
Issue 4

Methamphetamine (Meth) abuse is common among humans with immunodeficiency virus (HIV). The HIV-1 regulatory protein, trans-activator of transcription (Tat), has been described to induce changes in brain gene transcription that can result in impaired

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f505b1efb84dd393ebab634cee09bd
http://europepmc.org/articles/PMC7232389