Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Liana Adam"'
Autor:
Woonyoung Choi, Jay B Shah, Mai Tran, Robert Svatek, Lauren Marquis, I-Ling Lee, Dasom Yu, Liana Adam, Sijin Wen, Yu Shen, Colin Dinney, David J McConkey, Arlene Siefker-Radtke
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30206 (2012)
p63 is a member of the p53 family that has been implicated in maintenance of epithelial stem cell compartments. Previous studies demonstrated that p63 is downregulated in muscle-invasive bladder cancers, but the relationship between p63 expression an
Externí odkaz:
https://doaj.org/article/a788a84875854ccb8726896a82333bdf
Autor:
Colin Dinney, Menashe Bar-Eli, David McConkey, Arlene Siefker-Radtke, Hua Wang, George Calin, Ameeta Arora, Milena Nicoloso, Wei Qi, Woonyoung Choi, Meng Zhong, Liana Adam
Purpose: The epithelial-to-mesenchymal transition (EMT) is a cell development-regulated process in which noncoding RNAs act as crucial modulators. Recent studies have implied that EMT may contribute to resistance to epidermal growth factor receptor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3d8c9e63d5544adae6b58e2b7d997a
https://doi.org/10.1158/1078-0432.c.6517474
https://doi.org/10.1158/1078-0432.c.6517474
Autor:
Michael J. Overman, Paul Scheet, Scott Kopetz, Chad Huff, Stefan T. Arold, Ganiraju Manyam, Joe Ensor, Michael T. Tetzlaff, David Menter, Huamin Wang, Yulun Liu, Wenhui Wu, Yao Yu, Richard Fowler, F. Anthony San Lucas, Liana Adam
Purpose:Little is known about the genetic alterations characteristic of small bowel adenocarcinoma (SBA). Our purpose was to identify targetable alterations and develop experimental models of this disease.Experimental Design: Whole-exome sequencing (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d5881fedd9be635ffbe52a90db38d0
https://doi.org/10.1158/1078-0432.c.6529001
https://doi.org/10.1158/1078-0432.c.6529001
Autor:
Colin Dinney, Menashe Bar-Eli, David McConkey, Arlene Siefker-Radtke, Hua Wang, George Calin, Ameeta Arora, Milena Nicoloso, Wei Qi, Woonyoung Choi, Meng Zhong, Liana Adam
Conflict of Interest Form 1 from miR-200 Expression Regulates Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Reverses Resistance to Epidermal Growth Factor Receptor Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c55b3ae9e331773dec9c92877b6585
https://doi.org/10.1158/1078-0432.22440103
https://doi.org/10.1158/1078-0432.22440103
Autor:
Liana Adam, Menashe Bar-Eli, Alan J. Diehl, David J. McConkey, Gordon Brown, Colin P.N. Dinney, Wassim Kassouf
Activation of the epidermal growth factor receptor (EGFR) and downstream signaling pathways, such as phosphatidylinositol-3 kinase/Akt and Ras/mitogen-activated protein kinase (MAPK), have been implicated in causing resistance to EGFR-targeted therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53e8a4c586490409e225f0d55a22f03
https://doi.org/10.1158/0008-5472.c.6494133
https://doi.org/10.1158/0008-5472.c.6494133
Autor:
Liana Adam, Menashe Bar-Eli, Alan J. Diehl, David J. McConkey, Gordon Brown, Colin P.N. Dinney, Wassim Kassouf
Supplementary Figure 1 from Uncoupling between Epidermal Growth Factor Receptor and Downstream Signals Defines Resistance to the Antiproliferative Effect of Gefitinib in Bladder Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d4a96646c3c27057102060c4dc0090
https://doi.org/10.1158/0008-5472.22364322
https://doi.org/10.1158/0008-5472.22364322
Autor:
Stefan T. Arold, Huamin Wang, Ganiraju C. Manyam, Chad D. Huff, Richard G. Fowler, Scott Kopetz, Paul Scheet, Yao Yu, Yulun Liu, Joe Ensor, David G. Menter, Michael T. Tetzlaff, F. Anthony San Lucas, Liana Adam, Wenhui Wu, Michael J. Overman
Publikováno v:
Clinical Cancer Research. 25:641-651
Purpose: Little is known about the genetic alterations characteristic of small bowel adenocarcinoma (SBA). Our purpose was to identify targetable alterations and develop experimental models of this disease. Experimental Design: Whole-exome sequencing
Autor:
Rachna T. Shroff, J. Morris, Kanwal Pratap Singh Raghav, Scott Kopetz, Liana Adam, Michael J. Overman, David R. Fogelman, J. Wang, Arvind Dasari, Cathy Eng, Eduardo Vilar, Enusha Karunasena, Nilofer S. Azad, R. Pisanic, Robert A. Wolff, Bryan K. Kee
Background Hypermethylation of promoter CpG islands [CpG island methylator phenotype (CIMP)] represents a unique pathway for the development of colorectal cancer (CRC), characterized by lack of chromosomal instability and a low rate of adenomatous po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27d159bcf45db84d9859599c0cfe769
https://europepmc.org/articles/PMC5834085/
https://europepmc.org/articles/PMC5834085/
Autor:
T. R. Pisanic, Enusha Karunasena, David R. Fogelman, Robert A. Wolff, Scott Kopetz, Jing Wang, Liana Adam, J. Morris, Cathy Eng, Nilofer S. Azad, Eduardo Vilar, Michael J. Overman, Arvind Dasari, Kanwal Pratap Singh Raghav, Bryan K. Kee, Rachna T. Shroff
Publikováno v:
Annals of Oncology. 30:495
Autor:
Lixia Diao, Chang Gong Liu, David A. Jackson, Liana Adam, Alexander Zien, Colin P.N. Dinney, Wang Jing, Jitao D. Zhang, Matthew F. Wszolek
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 31:1701-1708
Bladder cancer (BC) is a burdensome disease with significant morbidity, mortality, and cost. The development of novel plasma-based biomarkers for BC diagnosis and surveillance could significantly improve clinical outcomes and decrease health expendit