Zobrazeno 1 - 10
of 313
pro vyhledávání: '"LianXin Liu"'
Autor:
Linmao Sun, Yufeng Liu, Xinyu Guo, Tianming Cui, Chenghui Wu, Jie Tao, Cheng Cheng, Qi Chu, Changyong Ji, Xianying Li, Hongrui Guo, Shuhang Liang, Huanran Zhou, Shuo Zhou, Kun Ma, Ning Zhang, Jiabei Wang, Yao Liu, Lianxin Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Despite the importance of spliceosome core components in cellular processes, their roles in cancer development, including hepatocellular carcinoma (HCC), remain poorly understood. In this study, we uncover a critical role for SmD2, a core co
Externí odkaz:
https://doaj.org/article/0a56ad98810e44d499f55cc5af8d6197
Autor:
Yabin Huang, Fanzheng Meng, Taofei Zeng, Rick Francis Thorne, Lifang He, Qingrui Zha, Hairui Li, Hong Liu, Chuandong Lang, Wanxiang Xiong, Shixiang Pan, Dalong Yin, Mian Wu, Xuedan Sun, Lianxin Liu
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-21 (2024)
Abstract Glutamine addiction represents a metabolic vulnerability of cancer cells; however, effective therapeutic targeting of the pathways involved remains to be realized. Here, we disclose the critical role of interferon-related developmental regul
Externí odkaz:
https://doaj.org/article/7d5757ae6e654746b24b061de00ba934
Autor:
Xiaoshi Zhang, Xiaodong Zhu, Jianhong Zhong, Yang Zhao, Xiaoyun Zhang, Wenwen Zhang, Feng Ye, Chaoxu Yang, Jun Xue, Rui Xiong, Jiabei Wang, Shunli Shen, Yangxun Pan, Dongxiao Li, Tianqiang Song, Xinyu Bi, Huichuan Sun, Bangde Xiang, Shanzhi Gu, Tianfu Wen, Shichun Lu, Yongjun Chen, Tao Yin, Lianxin Liu, Ming Kuang, Li Xu, Deyu Li, Jianqiang Cai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Systemic therapy is typically the primary treatment choice for hepatocellular carcinoma (HCC) patients with extrahepatic metastases. Some patients may achieve partial response (PR) or complete response (CR) with systemic treatment, leading t
Externí odkaz:
https://doaj.org/article/944b25832201457a937555fa1a98edab
Autor:
Yumin Fu, Xinyu Guo, Linmao Sun, Tianming Cui, Chenghui Wu, Jiabei Wang, Yao Liu, Lianxin Liu
Publikováno v:
eLife, Vol 13 (2024)
Hepatocellular carcinoma (HCC), the most common type of liver tumor, is a leading cause of cancer-related deaths, and the incidence of liver cancer is still increasing worldwide. Curative hepatectomy or liver transplantation is only indicated for a s
Externí odkaz:
https://doaj.org/article/0d8d4b5721f84204b14a71255c83eded
Autor:
Shenyu Zhang, Guibin Yang, Ruipeng Song, Wei Wang, Fanzheng Meng, Dalong Yin, Jiabei Wang, Shugeng Zhang, Wei Cai, Yao Liu, Dayong Luo, Jizhou Wang, Lianxin Liu
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Adjuvant therapy is used to reduce the risk of hepatocellular carcinoma (HCC) recurrence and improve patient prognosis. Exploration of treatment strategies that are both efficacious and safe has been extensively performed in the recent ye
Externí odkaz:
https://doaj.org/article/dbb9e1ae4476413d8328aaceb80b3baa
Autor:
Kun Ma, Junhui Chu, Yufeng Liu, Linmao Sun, Shuo Zhou, Xianying Li, Changyong Ji, Ning Zhang, Xinyu Guo, Shuhang Liang, Tianming Cui, Qingsong Hu, Jiabei Wang, Yao Liu, Lianxin Liu
Publikováno v:
Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)
Abstract Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer with a highly immunosuppressive tumor microenvironment and a typical pattern of disturbances in hepatic lipid metabolism. Long non‐coding RNAs are shown to play
Externí odkaz:
https://doaj.org/article/1ca886730c2f47b38f32b485fe17a36c
Autor:
Kun Chen, Xi Chen, Chuandong Lang, Xingshi Yuan, Junming Huang, Zhi Li, Mingyou Xu, Kerong Wu, Chenhe Zhou, Qidong Li, Chen Zhu, Lianxin Liu, Xifu Shang
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 9, Pp 2051-2066 (2023)
Abstract The identification of key regulatory factors that control osteoclastogenesis is important. Accumulating evidence indicates that circular RNAs (circRNAs) are discrete functional entities. However, the complexities of circRNA expression as wel
Externí odkaz:
https://doaj.org/article/3cb29d8e8aef4dad88abef4349cf2023
Autor:
Mingyue Li, Rick Francis Thorne, Ruijie Wang, Leixi Cao, Fangyuan Cheng, Xuedan Sun, Mian Wu, Jianli Ma, Lianxin Liu
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Sestrins are a small gene family of pleiotropic factors whose actions promote cell adaptation to a range of stress conditions. In this report we disclose the selective role of Sestrin2 (SESN2) in dampening aerobic glycolysis to adapt to limi
Externí odkaz:
https://doaj.org/article/efb2ef010eaf4b3393f1be40643b178b
Autor:
Jihua Han, Changming Xie, Tiemin Pei, Jiabei Wang, Yaliang Lan, Kaihua Huang, Yifeng Cui, Fengyue Wang, Jiewu Zhang, Shangha Pan, Yingjian Liang, Tongsen Zhen, Ruipeng Song, Boshi Sun, Yuejin Li, Huawen Shi, Guangchao Yang, Xirui Liu, Mingxi Zhu, Yan Wang, Keyu Li, Yao Liu, Fanzheng Meng, Fei Liao, Xianzhi Meng, Xuehui Hong, Lianxin Liu
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/798962075a804f6387c4e59614917ff5
Autor:
Yang Wu, Yichun Wang, Hanhui Yao, Heng Li, Fanzheng Meng, Qidong Li, Xiansheng Lin, Lianxin Liu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background Altered glycolysis is the most fundamental metabolic change associated with the Warburg effect. Some glycolytic enzymes such as PKM2, the dominant pyruvate kinase in cancer cells, have been shown to engage in non-glycolytic functi
Externí odkaz:
https://doaj.org/article/1524bc37999942bfab4b6efd0c1dcd10