Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lian-Wen Sun"'
The role of primary cilia in mechanical transmission of osteocyte based on a 3D finite element model
Publikováno v:
Medicine in Novel Technology and Devices, Vol 21, Iss , Pp 100275- (2024)
The primary cilium, as a mechanical receptor of osteocytes, participates in the regulation of osteocyte mechanosensitivity. However, how the length of osteocyte primary cilia changes with fluid shear stress (FSS) are unclear, and how the mechanical t
Externí odkaz:
https://doaj.org/article/73d86b98dee64b8781384dc72d9b96bb
Publikováno v:
Medicine in Novel Technology and Devices, Vol 16, Iss , Pp 100175- (2022)
Cortical bone is the main mechanical bearing structure of bone, and the mechanical properties of materials are not only related to bone mineral density, but also largely depend on its pores microstructure which affected by blood vessels. However, the
Externí odkaz:
https://doaj.org/article/9aa24408b72a4494b67bf2661a36af04
Publikováno v:
In Medicine in Novel Technology and Devices June 2023 18
Autor:
Cong-Jin Liu, Xiao Yang, Yan Mao, Xiao-Xue Zhang, Xin-Tong Wu, Shou-Hui Wang, Yu-Bo Fan, Lian-Wen Sun
Publikováno v:
Acta Astronautica. 206:114-122
Publikováno v:
Acta Astronautica. 205:163-171
Autor:
Cong-Jin Liu, Xiao Yang, Shou-Hui Wang, Xin-Tong Wu, Yan Mao, Jing-Wen Shi, Yu-Bo Fan, Lian-Wen Sun
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 5; Pages: 4953
Bone loss occurs in astronauts during long-term space flight, but the mechanisms are still unclear. We previously showed that advanced glycation end products (AGEs) were involved in microgravity-induced osteoporosis. Here, we investigated the improve
Publikováno v:
Computer Methods in Biomechanics and Biomedical Engineering. 26:249-260
Osteocytes play an important role in mechanosensation and conduction in bone tissue, and the change of mechanical environment can affect the sensitivity of osteocytes to external stimulation. The structure of osteocytes will be changed when they are
Autor:
Salanova, Dieter Blottner, Gabor Trautmann, Sandra Furlan, Guido Gambara, Katharina Block, Martina Gutsmann, Lian-Wen Sun, Paul F. Worley, Luisa Gorza, Martina Scano, Paola Lorenzon, Imre Vida, Pompeo Volpe, Michele
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 75
The molecular mechanisms of skeletal muscle atrophy under extended periods of either disuse or microgravity are not yet fully understood. The transition of Homer isoforms may play a key role during neuromuscular junction (NMJ) imbalance/plasticity in
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 36(2)
Decades of spaceflight studies have provided abundant evidence that individual cells in vitro are capable of sensing space microgravity and responding with cellular changes both structurally and functionally. However, how microgravity is perceived, t
Publikováno v:
Calcified Tissue International. 97:592-601
Advanced glycation end products (AGEs) accumulate in bone extracellular matrix as people age. Previous studies have shown controversial results regarding the role of in situ AGEs accumulation in osteoclastic resorption. To address this issue, this st