Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Lian-Shun Feng"'
Autor:
Zhi Xu, Shu Zhang, Lian-Shun Feng, Xiao-Ning Li, Guo-Cheng Huang, Yun Chai, Zao-Sheng Lv, Hui-Yuan Guo, Ming-Liang Liu
Publikováno v:
Molecules, Vol 22, Iss 7, p 1171 (2017)
A series of novel 8-OMe ciprofloxacin (CPFX)-hydrazone/azole hybrids were designed, synthesized, and evaluated for their in vitro biological activities. Our results reveal that all of the hydrozone-containing hybrids (except for 7) show potency again
Externí odkaz:
https://doaj.org/article/ce025dc21574453cbab34f7410f34424
Autor:
Lian-Shun Feng
Publikováno v:
Current topics in medicinal chemistry. 22(17)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b256f05d195b236f73e9c5eb34d194cc
https://pubmed.ncbi.nlm.nih.gov/36028932
https://pubmed.ncbi.nlm.nih.gov/36028932
Publikováno v:
Archiv der PharmazieREFERENCES. 355(7)
Cancer, as a long-lasting and dramatic disease, affects almost one-third of human beings globally. Chemotherapeutics play an important role in cancer treatment, but multidrug resistance and severe adverse effects have already become the main causes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db49a5168401d79276202c7e6f1fd24
https://pubmed.ncbi.nlm.nih.gov/35419808
https://pubmed.ncbi.nlm.nih.gov/35419808
Publikováno v:
Archiv der PharmazieREFERENCES. 355(6)
Cancer, characterized by a deregulation of the cell cycle which mainly results in a progressive loss of cellular differentiation and uncontrolled cellular growth, remains a prominent cause of death across the world. Almost all currently available ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9473e4a1ab609ddaad1a685b19f06792
https://pubmed.ncbi.nlm.nih.gov/35385159
https://pubmed.ncbi.nlm.nih.gov/35385159
Publikováno v:
Current topics in medicinal chemistry. 22(17)
Abstract: Cancer being one of the leading causes of death among non-communicable diseases, has already posed a heavy burden on the world health system. Chemotherapy is one of the most effec-tive approaches for cancer treatment, but multidrug resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce39f62c8840c124c5b456ca1a7224f8
https://pubmed.ncbi.nlm.nih.gov/36028933
https://pubmed.ncbi.nlm.nih.gov/36028933
Publikováno v:
European Journal of Medicinal Chemistry. 163:404-412
Tetrazole, a bioisostere of the carboxylic acid group, can replace the carboxyl group in drugs to increase the lipophilicity, bioavailability and reduce side effects. Tetrazole derivatives possess a broad-spectrum of biological properties including a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a4b678e1b4dc7e5e42e581e34bb7ec
https://doi.org/10.1016/j.ejmech.2018.12.001
https://doi.org/10.1016/j.ejmech.2018.12.001
Autor:
Lian-Shun Feng
Publikováno v:
Current topics in medicinal chemistry. 20(21)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290ac5195085435d7a1de9eae1c65e9f
https://pubmed.ncbi.nlm.nih.gov/32957869
https://pubmed.ncbi.nlm.nih.gov/32957869
Publikováno v:
Archiv der PharmazieREFERENCES. 354(1)
The human immunodeficiency virus type 1 (HIV-1) is the major etiological agent responsible for the acquired immunodeficiency syndrome (AIDS), which is a serious infectious disease and remains one of the most prevalent problems at present. Currently,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335eff9d33f43450aae8de5a2be5dc78
https://pubmed.ncbi.nlm.nih.gov/32960467
https://pubmed.ncbi.nlm.nih.gov/32960467
Publikováno v:
Journal of Heterocyclic Chemistry. 55:1263-1279
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b896cf8f7902436de65955d5897e30d
https://doi.org/10.1002/jhet.3189
https://doi.org/10.1002/jhet.3189
Publikováno v:
Current Topics in Medicinal Chemistry. 18:101-113
Bis-coumarins have caused great interests in the recent years. These compounds exhibit diverse biological activities which are ascribed to their ability to exert noncovalent interactions with the various active sites in organisms. Some of them such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fcbc04b18479943f70875172c4cb796
https://doi.org/10.2174/1568026618666180221114515
https://doi.org/10.2174/1568026618666180221114515