Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lian-Qun Qiu"'
Autor:
Lian-Qun Qiu1, Abey, Sarah1, Harris, Shawn2, Shah, Ruchir2, Gerrish, Kevin E.3, Blackshear, Perry J.1,4,5 Black009@niehs.nih.gov
Publikováno v:
Environmental Health Perspectives. Apr2015, Vol. 123 Issue 4, p324-330. 7p. 2 Charts, 3 Graphs.
Autor:
James Inglese, Franziska Bollmann, Lian-Qun Qiu, Keith R. Shockley, Perry J. Blackshear, Brittany L. Snyder
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eafe24d7967f471d08d29c3fa959f6a
https://doi.org/10.1096/fasebj.2018.32.1_supplement.826.9
https://doi.org/10.1096/fasebj.2018.32.1_supplement.826.9
Tristetraprolin (TTP) is a tandem CCCH zinc finger protein that can bind to AU-rich element-containing mRNAs and promote their decay. TTP knockout mice develop a severe inflammatory syndrome, largely due to excess tumor necrosis factor (TNF), whose m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d20f2962e0012eff2313e17a991d01
https://europepmc.org/articles/PMC5789023/
https://europepmc.org/articles/PMC5789023/
Publikováno v:
Journal of Leukocyte Biology. 97:723-736
TTP is an anti-inflammatory protein that acts by binding to AREs in its target mRNAs, such as Tnf mRNA, and promoting their deadenylation and decay. TNF released from inflammatory cells can then stimulate gene expression in tissue cells, such as fibr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49dde6e8bfbe4f5cf03edc5010f49b0c
https://doi.org/10.1189/jlb.3a0214-106r
https://doi.org/10.1189/jlb.3a0214-106r
Autor:
Kevin Gerrish, Lian-Qun Qiu, Perry J. Blackshear, Shawn F. Harris, Ruchir R. Shah, Sarah Abey
Publikováno v:
Environmental Health Perspectives
Background: Inorganic arsenic species are potent environmental toxins and causes of numerous health problems. Most studies have assumed that arsenic-induced changes in mRNA levels result from effects on gene transcription. Objectives: We evaluated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697034af7a70bcd005c35b9589f3a5df
http://europepmc.org/articles/PMC4383576
http://europepmc.org/articles/PMC4383576
Culture of mouse embryonic fibroblast (MEF) cells represents a powerful system to test gene function due to their easy accessibility, rapid growth rates, and the possibility of a large number of experiments. Fibroblasts are a group of heterogeneous r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03616970820f33e686e5bca37268937c
https://europepmc.org/articles/PMC5448408/
https://europepmc.org/articles/PMC5448408/
Publikováno v:
BIO-PROTOCOL. 6
mRNA stability control is a critical step in the post-transcriptional regulation of gene expression. Actinomycin D, an antibiotic initially used as an anti-cancer drug, has turned out to be a convenient tool for studying the turnover rates of transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df5fe28733825aa219d49062abd81cc
https://doi.org/10.21769/bioprotoc.1858
https://doi.org/10.21769/bioprotoc.1858
Publikováno v:
Blood. 113:3520-3529
Viperin (virus inhibitory protein, endoplasmic reticulum [ER]–associated, interferon-inducible) has been identified as a highly inducible ER protein that has antiviral activity. Here, we characterized the phenotype of mice deficient in viperin and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90607b9e6b410d26abcd4d3073ebd65f
https://doi.org/10.1182/blood-2008-07-171942
https://doi.org/10.1182/blood-2008-07-171942
Publikováno v:
Laboratory Investigation. 84:1112-1125
The activities of cell cycle regulatory proteins have been reported to be associated with the development of pathological lesions in glomerulonephritis. To assess the cellular mechanisms underlying the mesangial cell proliferation and glomerulosclero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6ba129bf78940cf7c22e5fa9b04e6b
https://doi.org/10.1038/labinvest.3700144
https://doi.org/10.1038/labinvest.3700144
Publikováno v:
Journal of the American Society of Nephrology. 15:79-90
Bcl-2 defines a new class of proto-oncogenes that block cell death without promoting cell proliferation. To elucidate the role of Bcl-2 in the development of glomerular lesions in human IgA nephropathy (IgAN), we applied immunohistochemistry coupled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494dfc866ddf522c7bec29685afff2dd
https://doi.org/10.1097/01.asn.0000104573.54132.2e
https://doi.org/10.1097/01.asn.0000104573.54132.2e