Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lian-Dong Guo"'
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-6 (2020)
Despite being known for more than 50 years, yuzurimine-type alkaloids have not been accessed by total synthesis. Here, the authors report the first enantioselective total synthesis of (+)-Caldaphnidine J, a highly complex yuzurimine-type Daphniphyllu
Externí odkaz:
https://doaj.org/article/56d24c15a8254f91bc01a6357360c039
Publikováno v:
Accounts of Chemical Research. 55:2326-2340
ConspectusThe six-membered heterocycles containing oxygen and nitrogen (tetrahydropyrans, pyrans, piperidines) are among the most common heterocyclic structures ubiquitously present in bioactive molecules such as carbohydrates, small-molecule drugs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914438d030d5338f8d0ba3b06326fdf5
https://doi.org/10.1021/acs.accounts.2c00358
https://doi.org/10.1021/acs.accounts.2c00358
Publikováno v:
Organic letters. 24(40)
Here, we report the first total syntheses of daphnezomine L-type alkaloids daphnezomine L methyl ester and calyciphylline K via late-stage C-N bond activation. The first synthesis of secodaphniphylline-type alkaloid caldaphnidine D was also achieved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4484a3a43b57e7624dccc454a90473c6
https://pubmed.ncbi.nlm.nih.gov/36191161
https://pubmed.ncbi.nlm.nih.gov/36191161
Publikováno v:
Chinese Journal of Chemistry. 38:1723-1736
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::395633252f040b0e9ab2001be44adfc7
https://doi.org/10.1002/cjoc.202000291
https://doi.org/10.1002/cjoc.202000291
Publikováno v:
Accounts of Chemical Research. 53:2726-2737
Native to the Asia-Pacific region and widely applied in traditional Chinese medicine, the genus Daphniphyllum has produced over 330 known Daphniphyllum alkaloids. Investigations into these alkaloids have shown an exceptional range of interesting bioa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de1751576f66bd0c5dc52f9b37eef9c9
https://doi.org/10.1021/acs.accounts.0c00532
https://doi.org/10.1021/acs.accounts.0c00532
Publikováno v:
Angewandte Chemie International Edition. 61
Paspaline-derived indole diterpenes (IDTs) are structurally complex mycotoxins with unique tremorgenic activity. Reported are asymmetric total syntheses of three paspaline-derived IDTs paspalicine, paspalinine and paspalinine-13-ene. Our synthesis fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42baa369bcf821d3c4a7c0bb2ad41290
https://doi.org/10.1002/anie.202115384
https://doi.org/10.1002/anie.202115384
Publikováno v:
Angewandte Chemie. 131:7468-7472
The daphniphyllum alkaloids are a structurally fascinating and remarkably diverse family of natural products. General strategies for the chemical synthesis of their challenging architectures are highly desirable for efficiently accessing these intrig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7901abf7408a574ff7b4ae88edbe46e2
https://doi.org/10.1002/ange.201902908
https://doi.org/10.1002/ange.201902908
Publikováno v:
Accounts of chemical research. 53(11)
Native to the Asia-Pacific region and widely applied in traditional Chinese medicine, the genus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c416d5d82a70a5d2afb844135e0495a
https://pubmed.ncbi.nlm.nih.gov/33074659
https://pubmed.ncbi.nlm.nih.gov/33074659
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-6 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-6 (2020)
Ever since Hirata’s report of yuzurimine in 1966, nearly fifty yuzurimine-type alkaloids have been isolated, which formed the largest subfamily of the Daphniphyllum alkaloids. Despite extensive synthetic studies towards this synthetically challengi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0094c48eec135b83e2f0511dccf4dc
https://doi.org/10.1038/s41467-020-17350-x
https://doi.org/10.1038/s41467-020-17350-x
Publikováno v:
Journal of the American Chemical Society. 141(29)
The intriguing structural complexity and bioactivities of the Daphniphyllum alkaloids have long attracted much attention. Herein, we report the first and enantioselective total synthesis of Daphniphyllum alkaloid dapholdhamine B and its lactone deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c13147fdad389c003d2649dd5bf966e7
https://pubmed.ncbi.nlm.nih.gov/31299155
https://pubmed.ncbi.nlm.nih.gov/31299155