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pro vyhledávání: '"Lian Chun Park"'
Autor:
Tomoaki Takata, Noriho Kamaiya, Masahiro Goto, Lian Chun Park, Hirofumi Ichinose, Tatsuo Maruyama
Publikováno v:
Biotechnology Letters. 25:1637-1641
A novel and simple method for detection of mutations in DNA oligonucleotides using a double-stranded DNA specific dye (SYBR Green I) is reported. The SYBR Green I is bound specifically with a duplex DNA oligonucleotide (intercalation). This intercala
Autor:
Hiroyuki Kuma, Noriho Kamiya, Masahiro Goto, Tatsuo Maruyama, Naotaka Hamasaki, Lian Chun Park
Publikováno v:
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 20(11)
The emergence of drug-resistant hepatitis B virus (HBV) has been reported in patients with prolonged administration of lamivudine, which is a potent drug for the prevention of HBV infection. Lamivudine-resistant HBV has several types of mutations at
Publikováno v:
Biomacromolecules. 5(1)
We have developed a simple single nucleotide polymorphisms (SNPs) analysis utilizing DNA hybridization in nanostructural molecular assemblies. The novel technique enables the detection of a single-base mismatch in a DNA sequence without a fluorescent
Publikováno v:
The Analyst. 128(2)
DNA hybridization was investigated in AOT (sodium di-2-ethylhexyl sulfosuccinate)/isooctane reverse micelles. The single-stranded DNA molecules were encapsulated in the nanoscale water pools formed in the reverse micelles, reducing the hybridization