Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Liaman K. Mamedova"'
Autor:
Pedro, Besada, Liaman K, Mamedova, Krishnan K, Palaniappan, Zhan-Guo, Gao, Bhalchandra V, Joshi, Lak Shin, Jeong, Mortimer M, Civan, Kenneth A, Jacobson
Publikováno v:
Collect Czechoslov Chem Commun
9-(β-D-Ribosfuranosyluronamide)adenine derivatives that are selective agonists and antagonists of the A(3) adenosine receptor (AR) have been derivatized as prodrugs for in vivo delivery. The free hydroxy groups at the 2′ and 3′ positions of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd9d3c2ff672a05d61b036feba86fbed
https://pubmed.ncbi.nlm.nih.gov/34815583
https://pubmed.ncbi.nlm.nih.gov/34815583
Publikováno v:
International Journal of Dairy Science. 6:134-141
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e31508a12e7572d9f65fbe81c2f9743
https://doi.org/10.3923/ijds.2011.134.141
https://doi.org/10.3923/ijds.2011.134.141
Autor:
Philippe Van Rompaey, Liaman K. Mamedova, Lak Shin Jeong, Kenneth A. Jacobson, Zhan-Guo Gao, Tatiana Sonina, Bruce T. Liang, Hea Ok Kim, Serge Van Calenbergh, Myong Jung Kim, Ae Yil Kim, Heng T. Duong, Soo-Kyung Kim
Publikováno v:
Journal of Medicinal Chemistry. 49:2689-2702
An alternative approach to overcome the inherent lack of specificity of conventional agonist therapy can be the reengineering of the GPCRs and their agonists. A reengineered receptor (neoceptor) could be selectively activated by a modified agonist, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1869e4ec511d5a70be139a77a0d0d6a4
https://doi.org/10.1021/jm050968b
https://doi.org/10.1021/jm050968b
Autor:
Pedro Besada, Bhalchandra V. Joshi, Zhan-Guo Gao, Mortimer M. Civan, Kenneth A. Jacobson, Lak Shin Jeong, Liaman K. Mamedova, Krishnan K. Palaniappan
Publikováno v:
Collection of Czechoslovak Chemical Communications. 71:912-928
9-(β-D-Ribosfuranosyluronamide)adenine derivatives that are selective agonists and antagonists of the A3 adenosine receptor (AR) have been derivatized as prodrugs for in vivo delivery. The free hydroxy groups at the 2' and 3' positions of the agonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9f9e4117b91e44778f73d19f069c830
https://doi.org/10.1135/cccc20060912
https://doi.org/10.1135/cccc20060912
Autor:
Valérie Capra, Maria P. Abbracchio, Zhan-Guo Gao, Marta Fumagalli, G. Enrico Rovati, Kenneth A. Jacobson, Silvia Ferrario, Maria Rosa Accomazzo, Liaman K. Mamedova
Publikováno v:
Biochemical Pharmacology. 71:115-125
Montelukast and pranlukast are orally active leukotriene receptor antagonists selective for the CysLT1 receptor. Conversely, the hP2Y(1,2,4,6,11,12,13,14) receptors represent a large family of GPCRs responding to either adenine or uracil nucleotides,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f055457904c0d9b8bfdc7af7160f0f3
https://doi.org/10.1016/j.bcp.2005.10.003
https://doi.org/10.1016/j.bcp.2005.10.003
Autor:
Liaman K. Mamedova, Kenneth A. Jacobson, Pedro Besada, Bhalchandra V. Joshi, Stefano Costanzi
Publikováno v:
Seminars in Thrombosis and Hemostasis. 31:205-216
Transmembrane signaling through P2Y receptors for extracellular nucleotides controls a diverse array of cellular processes, including thrombosis. Selective agonists and antagonists of the two P2Y receptors present on the platelet surface-the G (q)-co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1a8b849beabeef1ee6a0f0c2b31db4
https://doi.org/10.1055/s-2005-869526
https://doi.org/10.1055/s-2005-869526
Publikováno v:
Biochemical Pharmacology. 68:1985-1993
The affinity and efficacy at four subtypes (A(1), A(2A), A(2B) and A(3)) of human adenosine receptors (ARs) of a wide range of 2-substituted adenosine derivatives were evaluated using radioligand binding assays and a cyclic AMP functional assay in in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd148c304d870b816ecb95fc11bbac13
https://doi.org/10.1016/j.bcp.2004.06.011
https://doi.org/10.1016/j.bcp.2004.06.011
Publikováno v:
Biochemical Pharmacology. 68:231-237
The effect of 2,2'-pyridylisatogen tosylate (PIT) on the human P2Y(1) receptor and on other recombinant P2Y receptors has been studied. We first examined the modulation by PIT of the agonist-induced accumulation of inositol phosphates. PIT blocked 2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243e36c67d265147a7b1367aad486e58
https://doi.org/10.1016/j.bcp.2004.02.039
https://doi.org/10.1016/j.bcp.2004.02.039
Autor:
Zhan-Guo Gao, Bhalchandra V. Joshi, Kenneth A. Jacobson, Ivar von Kügelgen, Liaman K. Mamedova
Publikováno v:
Biochemical Pharmacology. 67:1763-1770
The physiological role of the P2Y(6) nucleotide receptor may involve cardiovascular, immune and digestive functions based on the receptor tissue distribution, and selective antagonists for this receptor are lacking. We have synthesized a series of sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011f1d50dd080bd6b91ac68594a5ffd7
https://doi.org/10.1016/j.bcp.2004.01.011
https://doi.org/10.1016/j.bcp.2004.01.011
Autor:
Mordechai Manoach, Tova Zinman, Vladimir Shneyvays, Asher Shainberg, Shay Moshel, Weismann P, Liaman K. Mamedova, Sawa Kostin, Narcis Tribulova
Publikováno v:
Journal of Molecular Histology. 35:463-470
This study examined whether triiodo-L-thyronine (T3) affects the expression of the major intercellular channel protein, connexin-43, and contractile protein alpha-sarcomeric actin. Cultured cardiomyocytes from newborn rats were treated on day three i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228297f190a5af9dfec61a8bfd513a44
https://doi.org/10.1023/b:hijo.0000045945.16046.b5
https://doi.org/10.1023/b:hijo.0000045945.16046.b5