Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Liam W. McQueen"'
Autor:
Liam W. McQueen, Shameem S. Ladak, Georgia R. Layton, Marcin Wozniak, Charles Solomon, Zein El-Dean, Gavin J. Murphy, Mustafa Zakkar
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10368 (2024)
Vein graft disease is the process by which saphenous vein grafts, utilised for revascularisation during coronary artery bypass graft surgery, undergo an inflammation-driven intimal hyperplasia and accelerated atherosclerosis process in subsequent yea
Externí odkaz:
https://doaj.org/article/c8c4695dd41243b992c0eb2ef7094752
Autor:
Liam W. McQueen, Shameem S. Ladak, Georgia R. Layton, Kerry Wadey, Sarah J. George, Gianni D. Angelini, Gavin J. Murphy, Mustafa Zakkar
Publikováno v:
Cells, Vol 12, Iss 22, p 2627 (2023)
Background: Osteopontin has been implicated in vascular calcification formation and vein graft intimal hyperplasia, and its expression can be triggered by pro-inflammatory activation of cells. The role of osteopontin and the temporal formation of mic
Externí odkaz:
https://doaj.org/article/46478f9df6d34283903e4173e362e5b6
Autor:
Georgia R. Layton, Shameem S. Ladak, Riccardo Abbasciano, Liam W. McQueen, Sarah J. George, Gavin J. Murphy, Mustafa Zakkar
Publikováno v:
Cells, Vol 12, Iss 5, p 815 (2023)
The long saphenous vein is the most used conduit in cardiac surgery, but its long-term patency is limited by vein graft disease (VGD). Endothelial dysfunction is a key driver of VGD; its aetiology is multi-factorial. However emerging evidence identif
Externí odkaz:
https://doaj.org/article/d7bf5d822f86483e8c2f12dd3fabdcfc
Autor:
Liam W. McQueen, Shameem S. Ladak, Riccardo Abbasciano, Sarah J. George, M-Saadeh Suleiman, Gianni D. Angelini, Gavin J. Murphy, Mustafa Zakkar
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Background and AimsAtherosclerosis is a chronic inflammatory disease that remains the leading cause of morbidity and mortality worldwide. Despite decades of research into the development and progression of this disease, current management and treatme
Externí odkaz:
https://doaj.org/article/edfa9c17da6b4494a0c7e239e8af1583
Autor:
Shameem S. Ladak, Liam W. McQueen, Georgia R. Layton, Hardeep Aujla, Adewale Adebayo, Mustafa Zakkar
Publikováno v:
Cells, Vol 11, Iss 19, p 3066 (2022)
Endothelial cells comprise the intimal layer of the vasculature, playing a crucial role in facilitating and regulating aspects such nutrient transport, vascular homeostasis, and inflammatory response. Given the importance of these cells in maintainin
Externí odkaz:
https://doaj.org/article/d4ef66735dd04e39a78718132611cf64
Autor:
Liam W. McQueen, Shameem S. Ladak, Riccardo Abbasciano, Sarah J. George, M-Saadeh Suleiman, Gianni D. Angelini, Gavin J. Murphy, Mustafa Zakkar
Publikováno v:
McQueen, L W, Ladak, S S, Abbasciano, R, George, S J, Suleiman, M-S, Angelini, G D, Murphy, G J & Zakkar, M 2022, ' Next-Generation and Single-Cell Sequencing Approaches to Study Atherosclerosis and Vascular Inflammation Pathophysiology : A Systematic Review ', Frontiers in Cardiovascular Medicine, vol. 9, 849675 . https://doi.org/10.3389/fcvm.2022.849675
Background and AimsAtherosclerosis is a chronic inflammatory disease that remains the leading cause of morbidity and mortality worldwide. Despite decades of research into the development and progression of this disease, current management and treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2affab75a6f03d3bee53017f7c8b9dee
https://research-information.bris.ac.uk/ws/files/322054258/fcvm_09_849675_1_.pdf
https://research-information.bris.ac.uk/ws/files/322054258/fcvm_09_849675_1_.pdf
Autor:
Oluwatomini Fashina, Riccardo G Abbasciano, Liam W McQueen, Shameem Ladak, Sarah J George, Sadeeh Suleiman, Prakash P Punjabi, Gianni D Angelini, Mustafa Zakkar
Publikováno v:
Perfusion. :026765912210912
Coronary artery bypass grafting remains the treatment of choice for a large cohort of patients with significant coronary disease. Despite the increased use of arterial grafts, the long saphenous vein remains the most commonly used conduit. Long-term
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 144:106173
The long saphenous vein is commonly used in cardiac surgery to bypass occluded coronary arteries. Its use is complicated by late stenosis and occlusion due to the development of intimal hyperplasia. It is accepted that intimal hyperplasia is a multif