Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Liam Town"'
Autor:
Liam Town, Edwina McGlinn, Tara-Lynne Davidson, Catherine M Browne, Kallayanee Chawengsaksophak, Peter Koopman, Joy M Richman, Carol Wicking
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25228 (2011)
The Tmem26 gene encodes a novel protein that we have previously shown to be regulated by hedgehog signalling in the mouse limb. We now report that Tmem26 expression is spatially and temporally restricted in other regions of the mouse embryo, most not
Externí odkaz:
https://doaj.org/article/51b34c37d2704496959e2675818e8d07
Autor:
Liam Town
The hedgehog morphogenic pathway is essential for the development of numerous organs and tissues in both vertebrates and invertebrates, and dysregulation of hedgehog signalling is also associated with a broad range of mammalian cancers. While a great
Externí odkaz:
http://espace.library.uq.edu.au/view/UQ:185675
Autor:
Kelly K. O’Brien, Francisco Ibáñez-Carrasco, Kelly Birtwell, Graeme Donald, Darren A. Brown, Andrew D. Eaton, Bakita Kasadha, Emma Stanmore, Natalie St. Clair-Sullivan, Liam Townsend, Jaime H. Vera, Patricia Solomon
Publikováno v:
AIDS Research and Therapy, Vol 20, Iss 1, Pp 1-10 (2023)
Abstract Background In 2016, the Canada-International HIV and Rehabilitation Research Collaborative established a framework of research priorities in HIV, aging and rehabilitation. Our aim was to review and identify any new emerging priorities from t
Externí odkaz:
https://doaj.org/article/9aabd4af905f4a43b4714040dc297c0b
Autor:
Eva M, Putz, Alyce J, Mayfosh, Kevin, Kos, Deborah S, Barkauskas, Kyohei, Nakamura, Liam, Town, Katharine J, Goodall, Dean Y, Yee, Ivan Kh, Poon, Nikola, Baschuk, Fernando, Souza-Fonseca-Guimaraes, Mark D, Hulett, Mark J, Smyth
Publikováno v:
The Journal of clinical investigation. 127(7)
NK cells are highly efficient at preventing cancer metastasis but are infrequently found in the core of primary tumors. Here, have we demonstrated that freshly isolated mouse and human NK cells express low levels of the endo-β-D-glucuronidase hepara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::36099f30abcd93eb72be852f75dd6f4a
https://pubmed.ncbi.nlm.nih.gov/28581441
https://pubmed.ncbi.nlm.nih.gov/28581441
Autor:
Daniel M. Andrews, Christopher J. Chan, Marco Colonna, Melvyn T. Chow, Liam Town, Ludovic Martinet, Mark J. Smyth, David Ritchie, Susan Gilfillan, Fernando Souza-Fonseca-Guimaraes
Publikováno v:
Nature Immunology. 15:431-438
CD96, CD226 (DNAM-1) and TIGIT belong to an emerging family of receptors that interact with nectin and nectin-like proteins. CD226 activates natural killer (NK) cell-mediated cytotoxicity, whereas TIGIT reportedly counterbalances CD226. In contrast,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12edc57536f2e751cd00d94782e8805d
https://doi.org/10.1038/ni.2850
https://doi.org/10.1038/ni.2850
Autor:
Nikaïa Smith, Céline Possémé, Vincent Bondet, Jamie Sugrue, Liam Townsend, Bruno Charbit, Vincent Rouilly, Violaine Saint-André, Tom Dott, Andre Rodriguez Pozo, Nader Yatim, Olivier Schwartz, Minerva Cervantes-Gonzalez, Jade Ghosn, Paul Bastard, Jean Laurent Casanova, Tali-Anne Szwebel, Benjamin Terrier, Niall Conlon, Cliona O’Farrelly, Clíona Ní Cheallaigh, Nollaig M. Bourke, Darragh Duffy
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The interferon response has been shown to be linked to severity of SARS-CoV-2 infection and is an essential component of the immune response to COVID-19. Here the authors stratify patients according to COVID-19 severity and asses the interferon respo
Externí odkaz:
https://doaj.org/article/0d29652ba4744077b01276da4fa055aa
Autor:
Nicholas D. Huntington, Jessica Rabilloud, Amélien Sanlaville, Sophie Degouve, Jacqueline Marvel, Sébastien Viel, Fernando Souza Fonseca Guimaraes, Sophia Djebali, Antoine Marçais, Morgan Grau, Mark J. Smyth, Thierry Walzer, Emily Charrier, Jacques Bienvenu, Róisín M. Loftus, Liam Town, David K. Finlay, Christophe Caux, Laurent Bartholin, Julien C. Marie
Publikováno v:
Science Signaling
Science Signaling, American Association for the Advancement of Science, 2016, 9 (415), pp.ra19-ra19. ⟨10.1126/scisignal.aad1884⟩
Science Signaling, 2016, 9 (415), pp.ra19-ra19. ⟨10.1126/scisignal.aad1884⟩
Science Signaling, American Association for the Advancement of Science, 2016, 9 (415), pp.ra19-ra19. ⟨10.1126/scisignal.aad1884⟩
Science Signaling, 2016, 9 (415), pp.ra19-ra19. ⟨10.1126/scisignal.aad1884⟩
International audience; Transforming growth factor-beta (TGF-beta) is a major immunosuppressive cytokine that maintains immune homeostasis and prevents autoimmunity through its antiproliferative and anti-inflammatory properties in various immune cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ab34fa0525f63f70c4aa737c517f1d
https://hal-univ-lyon1.archives-ouvertes.fr/hal-01796190
https://hal-univ-lyon1.archives-ouvertes.fr/hal-01796190
Autor:
Alyson Ashe, Natalie C. Butterfield, Rachael Barry, Carol Wicking, Kathryn V. Anderson, Andrew D. Courtney, Robert G. Parton, Karel F. Liem, Liam Town, Charles Ferguson, Fredrik Olsson, Ashley N. Cooper, Emma Whitelaw, Brandon J. Wainwright
Publikováno v:
Human Molecular Genetics. 21:1808-1823
Mutations in components of the intraflagellar transport (IFT) machinery required for assembly and function of the primary cilium cause a subset of human ciliopathies characterized primarily by skeletal dysplasia. Recently, mutations in the IFT-A gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15777be3a9a551e8b96b770b25239553
https://doi.org/10.1093/hmg/ddr613
https://doi.org/10.1093/hmg/ddr613
Autor:
Edwina McGlinn, Stephen J. Bruce, Natalie C. Butterfield, Carol Wicking, Vicki Metzis, Liam Town
Publikováno v:
Journal of Biological Chemistry. 285:27967-27981
The bones of the vertebrate limb form by the process of endochondral ossification, whereby limb mesenchyme condenses to form an intermediate cartilage scaffold that is then replaced by bone. Although Indian hedgehog (IHH) is known to control hypertop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ffd5b047bde4548a4a3848ae547185e
https://doi.org/10.1074/jbc.m109.091785
https://doi.org/10.1074/jbc.m109.091785
Autor:
Nathaniel Francis Brown, Jennifer L. Stow, Markus C. Kerr, Darren L. Brown, Frederic A. Meunier, Natalie A Castro, Rohan D. Teasdale, Liam Town, Nicholas A. Hamilton, Jack T. H. Wang
Publikováno v:
The EMBO Journal. 29:1331-1347
3-phosphorylated phosphoinositides (3-PtdIns) orchestrate endocytic trafficking pathways exploited by intracellular pathogens such as Salmonella to gain entry into the cell. To infect the host, Salmonellae subvert its normal macropinocytic activity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5df19cbd14a41c78092d2716d988fa20
https://doi.org/10.1038/emboj.2010.28
https://doi.org/10.1038/emboj.2010.28