Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Liam Shiels"'
Autor:
Kathryn H. Brown, Brianna N. Kerr, Mihaela Pettigrew, Kate Connor, Ian S. Miller, Liam Shiels, Colum Connolly, Conor McGarry, Annette T. Byrne, Karl T. Butterworth
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 31, Iss , Pp 100615- (2024)
Background and purpose: Radiomics analysis extracts quantitative data (features) from medical images. These features could potentially reflect biological characteristics and act as imaging biomarkers within precision medicine. However, there is a lac
Externí odkaz:
https://doaj.org/article/2be7e99c676a450782c0e39431b9e40d
Autor:
Anne-Marie Baird, David Easty, Monika Jarzabek, Liam Shiels, Alex Soltermann, Sonja Klebe, Stéphane Raeppel, Lauren MacDonagh, Chengguang Wu, Kim Griggs, Michaela B. Kirschner, Bryan Stanfill, Daisuke Nonaka, Chandra M. Goparaju, Bruno Murer, Dean A. Fennell, Dearbhaile M. O'Donnell, Martin P. Barr, Luciano Mutti, Glen Reid, Stephen Finn, Sinead Cuffe, Harvey I. Pass, Isabelle Opitz, Annette T. Byrne, Kenneth J. O'Byrne, Steven G. Gray
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Malignant pleural mesothelioma (MPM) is an aggressive inflammatory cancer with a poor survival rate. Treatment options are limited at best and drug resistance is common. Thus, there is an urgent need to identify novel therapeutic targets in this dise
Externí odkaz:
https://doaj.org/article/567be960042e4cd789610ded3489753b
Autor:
Alice C O'Farrell, Rhys Evans, Johanna M U Silvola, Ian S Miller, Emer Conroy, Suzanne Hector, Maurice Cary, David W Murray, Monika A Jarzabek, Ashwini Maratha, Marina Alamanou, Girish Mallya Udupi, Liam Shiels, Celine Pallaud, Antti Saraste, Heidi Liljenbäck, Matti Jauhiainen, Vesa Oikonen, Axel Ducret, Paul Cutler, Fionnuala M McAuliffe, Jacques A Rousseau, Roger Lecomte, Suzanne Gascon, Zoltan Arany, Bonnie Ky, Thomas Force, Juhani Knuuti, William M Gallagher, Anne Roivainen, Annette T Byrne
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169964 (2017)
Sunitinib is a tyrosine kinase inhibitor approved for the treatment of multiple solid tumors. However, cardiotoxicity is of increasing concern, with a need to develop rational mechanism driven approaches for the early detection of cardiac dysfunction
Externí odkaz:
https://doaj.org/article/a50b8f08c3d74280a693b5b4bb9f1718
Autor:
Lorraine O'Driscoll, Annette T. Byrne, Martina Gogarty, John Crown, Norma O'Donovan, Brigid C. Browne, Martina S. McDermott, Stephen Madden, Susan Breslin, Serena Germano, Liam Shiels, Claire Corcoran, Sweta Rani
Suppl Table 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5293c1f2b98c387442f19c7277b03110
https://doi.org/10.1158/0008-5472.22400151.v1
https://doi.org/10.1158/0008-5472.22400151.v1
Autor:
Lorraine O'Driscoll, Annette T. Byrne, Martina Gogarty, John Crown, Norma O'Donovan, Brigid C. Browne, Martina S. McDermott, Stephen Madden, Susan Breslin, Serena Germano, Liam Shiels, Claire Corcoran, Sweta Rani
Suppl Fig. S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d82f1e0ad1409f0447e60cf799846d
https://doi.org/10.1158/0008-5472.22400157
https://doi.org/10.1158/0008-5472.22400157
Autor:
Lorraine O'Driscoll, Annette T. Byrne, Martina Gogarty, John Crown, Norma O'Donovan, Brigid C. Browne, Martina S. McDermott, Stephen Madden, Susan Breslin, Serena Germano, Liam Shiels, Claire Corcoran, Sweta Rani
Suppl Material & Suppl. Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192dc31115bc0bae4709ee2006e1170a
https://doi.org/10.1158/0008-5472.22400154
https://doi.org/10.1158/0008-5472.22400154
Autor:
Lorraine O'Driscoll, Annette T. Byrne, Martina Gogarty, John Crown, Norma O'Donovan, Brigid C. Browne, Martina S. McDermott, Stephen Madden, Susan Breslin, Serena Germano, Liam Shiels, Claire Corcoran, Sweta Rani
Intrinsic and acquired resistance to HER-targeting drugs occurs in a significant proportion of HER2-overexpressing breast cancers. Thus, there remains a need to identify predictive biomarkers that could improve patient selection and circumvent these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3fb3e6daf7b5417bc44f37d65ce3c8b
https://doi.org/10.1158/0008-5472.c.6505512
https://doi.org/10.1158/0008-5472.c.6505512
Autor:
James Clerkin, Kate Connor, Kieron White, Kieron Sweeney, Liam Shiels, Thomas Van Brussel, Ingrid Arijs, Diether Lambrechts, Stephen Maher, Laure Marignol, Jochen Prehn, David O'Brien, Annette Byrne
Publikováno v:
Neuro-Oncology. 24:vii296-vii297
Clinically faithful pre-clinical models are essential for screening therapies and studying resistance mechanisms. Historically models have failed to predict response in the clinical setting. Current models seldom incorporate surgical resection, and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7651d7d33a6c9dfa21b55470181d975c
https://doi.org/10.1093/neuonc/noac209.1154
https://doi.org/10.1093/neuonc/noac209.1154
Autor:
Kate Connor, Emer Conroy, Kieron White, Liam Shiels, Simon Keek, Abdalla Ibrahim, William Gallagher, James Clerkin, Kieron Sweeney, David O'Brien, Jane Cryan, Josephine Heffernan, Francesca Brett, Philippe Lambin, Henry Woodruff, Annette Byrne
Publikováno v:
Neuro-Oncology. 24:vii295-vii296
While magnetic resonance imaging (MRI) is the predominant imaging modality for glioblastoma (GBM), pre-clinical MRI scanner availability is limited. As pre-clinical CT is more widely available and cost-effective, this study aimed to 1) establish prec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffde08caa56df0cb118eaa6e78be3ef6
https://doi.org/10.1093/neuonc/noac209.1151
https://doi.org/10.1093/neuonc/noac209.1151
Autor:
Kate Connor, Emer Conroy, Kieron White, Liam Shiels, William M Gallagher, Simon Keek, Abdalla Ibrahim, James Clerkin, David O’Brien, Philippe Lambin, Henry C Woodruff, Annette Byrne
Publikováno v:
WFNOS 2022 Abstract Book.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37e8b13726c5779d3c7a7c1a504af0b5
https://doi.org/10.14791/btrt.2022.10.f-1133
https://doi.org/10.14791/btrt.2022.10.f-1133