Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Liam R. Cox"'
Autor:
Alice R. Moorey, Alejandro Cabanillas, Sarah M. Batt, Sonja Ghidelli-Disse, Beatriz Urones, Olalla Sanz, Joel Lelievre, Marcus Bantscheff, Liam R. Cox, Gurdyal S. Besra
Publikováno v:
The Cell Surface, Vol 7, Iss , Pp 100068- (2021)
The emergence of drug-resistant strains of Mycobacterium tuberculosis (Mtb) ensures that drug discovery efforts remain at the forefront of TB research. There are multiple different experimental approaches that can be employed in the discovery of anti
Externí odkaz:
https://doaj.org/article/a33fd1f698b0424ca7a367765fd2c89c
Autor:
Peter J. Jervis, Liam R. Cox
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 3, Iss 1, p 6 (2007)
BackgroundUsing a silyl tether to unite an aldehyde electrophile and allylsilane nucleophile into a single molecule allows a subsequent Lewis-acid-mediated allylation to proceed in an intramolecular sense and therefore receive all the benefits associ
Externí odkaz:
https://doaj.org/article/0306737f57fa4e9a8fff0e2e4ca7be76
Autor:
Philip N. Jemmett, David C. Milan, Richard J. Nichols, Thomas Howitt, Alexandra L. Martin, Thomas Arnold, Jonathan L. Rawle, Christopher L. Nicklin, Timothy R. Dafforn, Liam R. Cox, Sarah L. Horswell
Publikováno v:
Langmuir. 38:14290-14301
Sphingolipids are an important class of lipids found in mammalian cell membranes with important structural and signaling roles. They differ from another major group of lipids, the glycerophospholipids, in the connection of their hydrocarbon chains to
Autor:
Amirpasha Moetazedian, Alessia Candeo, Siyun Liu, Arran Hughes, Vahid Nasrollahi, Mozafar Saadat, Andrea Bassi, Liam M. Grover, Liam R. Cox, Gowsihan Poologasundarampillai
Publikováno v:
Advanced Healthcare Materials.
Autor:
Francesca K. Lewns, Olga Tsigkou, Liam R. Cox, Ricky D. Wildman, Liam M. Grover, Gowsihan Poologasundarampillai
Publikováno v:
Advanced Materials.
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 37(40)
Lipid bilayers form the basis of biological cell membranes, selective and responsive barriers vital to the function of the cell. The structure and function of the bilayer are controlled by interactions between the constituent molecules and so vary wi
Autor:
Liam R. Cox, Amareeta K. Besra, Himanshu Kharkwal, Natacha Veerapen, Gurdyal S. Besra, Alan Howell, Christopher T. Johndrow, Lianjun Zhang, Noemi Alejandra Saavedra-Avila, Peter J. Jervis, Leandro J. Carreño, Elizabeth E. Evans, Steven A. Porcelli, Samantha Rothberg, Alena Donda, Steven C. Almo, Maurice Zauderer, Shalu Sharma Kharkwal, Scott J. Garforth, Jinghang Zhang
Publikováno v:
Cancer Res
CD1d-restricted invariant natural killer T cells (iNKT cells) mediate strong antitumor immunity when stimulated by glycolipid agonists. However, attempts to develop effective iNKT cell agonists for clinical applications have been thwarted by potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9e51cc5ecf1296bf2eb078435815ad
https://europepmc.org/articles/PMC8137529/
https://europepmc.org/articles/PMC8137529/
Autor:
Martin L. Read, Caitlin Thornton, Hannah Nieto, Liam R. Cox, Vicki Smith, Rashida Khan, Holly V. Adcock, Luke J. Alderwick, Christopher McCabe, Katie Brookes, Alice Fletcher, Mohammed Alshahrani, Jamie R.M. Webster, Kristien Boelaert
Publikováno v:
Endocrine Abstracts.
Autor:
Natacha Veerapen, David M. Lewinsohn, Mariolina Salio, Anne W. J. Martens, Wael Awad, Corinna Kulicke, Claudia Gonzalez-Lopez, Vincenzo Cerundolo, Dominic Waithe, Judith V. Hobrath, Liam R. Cox, Gurdyal S. Besra, Jamie Rossjohn
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 117(19), 10465-10475. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 117(19), 10465-10475. National Academy of Sciences
Significance MR1 is a monomorphic major histocompatibility complex (MHC) class I-like molecule that presents ligands to Mucosal Associated Invariant T cells. MR1 antigen presentation at the cell surface is tightly regulated by ligand availability. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e8ec78172338967f83c3a2ae2fb5dd
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48211 (2012)
The biosynthesis of mycobacterial mannose-containing lipoglycans, such as lipomannan (LM) and the immunomodulator lipoarabinomanan (LAM), is carried out by the GT-C superfamily of glycosyltransferases that require polyprenylphosphate-based mannose (P
Externí odkaz:
https://doaj.org/article/f6123076a9af418eb0795f1125c797b4