Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Liam P. Tuffy"'
Autor:
Matthieu Hammer, Dilja Krueger-Burg, Liam Patrick Tuffy, Benjamin Hillman Cooper, Holger Taschenberger, Sarit Pati Goswami, Hannelore Ehrenreich, Peter Jonas, Frederique Varoqueaux, Jeong-Seop Rhee, Nils Brose
Publikováno v:
Cell Reports, Vol 13, Iss 3, Pp 516-523 (2015)
Loss-of-function mutations in the synaptic adhesion protein Neuroligin-4 are among the most common genetic abnormalities associated with autism spectrum disorders, but little is known about the function of Neuroligin-4 and the consequences of its los
Externí odkaz:
https://doaj.org/article/667388ddc3cc4c2a98b9a39a1297d127
Autor:
Silvia Ripamonti, Mateusz C Ambrozkiewicz, Francesca Guzzi, Marta Gravati, Gerardo Biella, Ingo Bormuth, Matthieu Hammer, Liam P Tuffy, Albrecht Sigler, Hiroshi Kawabe, Katsuhiko Nishimori, Mauro Toselli, Nils Brose, Marco Parenti, JeongSeop Rhee
Publikováno v:
eLife, Vol 6 (2017)
Beyond its role in parturition and lactation, oxytocin influences higher brain processes that control social behavior of mammals, and perturbed oxytocin signaling has been linked to the pathogenesis of several psychiatric disorders. However, it is st
Externí odkaz:
https://doaj.org/article/74bbc3c9e85040aabd40e4e160d2ca42
Autor:
Bekir Altas, Liam P. Tuffy, Annarita Patrizi, Kalina Dimova, Tolga Soykan, Andrea J. Romanowski, Colin D. Robertson, Saovleak N. Khim, Garrett W. Bunce, Mateusz C. Ambrozkiewicz, Oleksandr Yagensky, Dilja Krueger-Burg, Matthieu Hammer, He-Hsuan Hsiao, Pawel R. Laskowski, Lydia Dyck, Marco Sassoè-Pognetto, John J.E. Chua, Henning Urlaub, Olaf Jahn, Nils Brose, Alexandros Poulopoulos
Neuroligin-3 is a postsynaptic adhesion molecule involved in development, function, and pathologies of synapses in the brain. It is a genetic cause of autism and a potent component of the tumor microenvironment in gliomas. There are four Neuroligins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e76691efe7cb44aad12171d782def37
https://doi.org/10.1101/2022.07.23.501257
https://doi.org/10.1101/2022.07.23.501257
Autor:
Liam P. Tuffy, Holger Taschenberger, Nils Brose, Hannelore Ehrenreich, Matthieu Hammer, Sarit Pati Goswami, Frederique Varoqueaux, Jeong-Seop Rhee, Peter Jonas, Dilja Krueger-Burg, Benjamin H. Cooper
Publikováno v:
Cell reports
Cell Reports
Cell Reports, Vol 13, Iss 3, Pp 516-523 (2015)
Cell Reports
Cell Reports, Vol 13, Iss 3, Pp 516-523 (2015)
Summary Loss-of-function mutations in the synaptic adhesion protein Neuroligin-4 are among the most common genetic abnormalities associated with autism spectrum disorders, but little is known about the function of Neuroligin-4 and the consequences of
Autor:
Mauro Toselli, Marco Parenti, Nils Brose, Jeong-Seop Rhee, Mateusz C. Ambrozkiewicz, Francesca Guzzi, Gerardo Biella, Liam P. Tuffy, Marta Gravati, Ingo Bormuth, Matthieu Hammer, Katsuhiko Nishimori, Silvia Ripamonti, Hiroshi Kawabe, Albrecht Sigler
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Beyond its role in parturition and lactation, oxytocin influences higher brain processes that control social behavior of mammals, and perturbed oxytocin signaling has been linked to the pathogenesis of several psychiatric disorders. However, it is st
Autor:
Mauro Toselli, Francesca Guzzi, Ingo Bormuth, Matthieu Hammer, Katsuhiko Nishimori, Silvia Ripamonti, Gerardo Biella, Hiroshi Kawabe, Mateusz C. Ambrozkiewicz, Liam P. Tuffy, Jeong-Seop Rhee, Marta Gravati, Marco Parenti, Nils Brose, Albrecht Sigler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::858310cc68a8863ada3528b1997f53cf
https://doi.org/10.7554/elife.22466.027
https://doi.org/10.7554/elife.22466.027
Autor:
Frederique Varoqueaux, Liam P. Tuffy, Nils Brose, Alexandros Poulopoulos, Tolga Soykan, Matthieu Hammer
Publikováno v:
Biochemical Journal; Vol 446
Biochemical Journal
Biochemical Journal
Neuroligins are postsynaptic adhesion proteins involved in the establishment of functional synapses in the central nervous system. In rodents, four genes give rise to neuroligins that function at distinct synapses, with corresponding neurotransmitter
Publikováno v:
Current Opinion in Neurobiology; Vol 22
Current Opinion in Neurobiology
Current Opinion in Neurobiology
Neurexins (NXs) and neuroligins (NLs) are transsynaptically interacting cell adhesion proteins that play a key role in the formation, maturation, activity-dependent validation, and maintenance of synapses. As complex alternative splicing processes in
Autor:
Petronela Weisová, David Dávila, Liam P. Tuffy, Caoimhín G. Concannon, Jochen H. M. Prehn, Manus W. Ward
Publikováno v:
Antioxidants & Redox Signaling. 14:1863-1876
5'-Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a key sensor of cellular energy status. AMPK signaling regulates energy balance at the cellular, organ, and whole-body level. More recently, it has become apparent that AMPK plays al
Autor:
Matthew A. King, Caoimhín G. Concannon, Heinrich J. Huber, Beatrice D'Orsi, Ina Woods, Manus W. Ward, Jochen H. M. Prehn, Liam P. Tuffy
Publikováno v:
Molecular and Cellular Biology. 30:5484-5501
Proteasomal stress and the accumulation of polyubiquitinated proteins are key features of numerous neurodegenerative disorders. Previously we demonstrated that stabilization of p53 and activation of its target gene, puma (p53-upregulated mediator of