Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Liam M. Grover"'
Autor:
Amy J Naylor, Simon W Jones, Liam M Grover, Thomas Nicholson, James Edwards, Kieran Patrick, Jonathan W Lewis, Hannah C Lamont, Kathryn Frost, Binal Patel, Miruna Chipara, Laurence A Hill, Georgiana Neag, Melissa Finlay
Publikováno v:
F1000Research, Vol 12 (2024)
Background There are insufficient in vitro bone models that accommodate long-term culture of osteoblasts and support their differentiation to osteocytes. The increased demand for effective therapies for bone diseases, and the ethical requirement to r
Externí odkaz:
https://doaj.org/article/6df289861d374cf88443e970916419f1
Autor:
Scott P. Davies, Vincenzo Ronca, Grace E. Wootton, Natalia M. Krajewska, Amber G. Bozward, Rémi Fiancette, Daniel A. Patten, Katharina Yankouskaya, Gary M. Reynolds, Sofia Pat, Daniel C. Osei-Bordom, Naomi Richardson, Liam M. Grover, Christopher J. Weston, Ye H. Oo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract The presence of CD8+ T cells in the cytoplasm of biliary epithelial cells (BEC) has been correlated with biliary damage associated with primary biliary cholangitis (PBC). Here, we characterise the mechanism of CD8+ T cell invasion into BEC.
Externí odkaz:
https://doaj.org/article/8c5d5d80fa404d79a9d64d2f03722925
Autor:
Amy J Naylor, Simon W Jones, Liam M Grover, Thomas Nicholson, James Edwards, Kieran Patrick, Jonathan W Lewis, Hannah C Lamont, Kathryn Frost, Binal Patel, Miruna Chipara, Laurence A Hill, Georgiana Neag, Melissa Finlay
Publikováno v:
F1000Research, Vol 12 (2024)
Background There are insufficient in vitro bone models that accommodate long-term culture of osteoblasts and support their differentiation to osteocytes. The increased demand for effective therapies for bone diseases, and the ethical requirement to r
Externí odkaz:
https://doaj.org/article/b76abd1f90334018a55f178824171e2b
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-9 (2023)
Abstract Heterotopic ossification (HO), the pathological formation of bone in soft tissues, is a debilitating condition, as well as one of the few instances of de novo bone formation in adults. Chemical mapping of HO tissue showed distinct islands of
Externí odkaz:
https://doaj.org/article/320dcc4f76174437a2b06e356a0baefc
Autor:
Thomas E. Robinson, Mathieu Y. Brunet, Iain Chapple, Adrian H. M. Heagerty, Anthony D. Metcalfe, Liam M. Grover
Publikováno v:
Advanced NanoBiomed Research, Vol 3, Iss 9, Pp n/a-n/a (2023)
Fibrotic diseases account for 45% of all deaths in the developed world, and progressive scarring conditions, such as dystrophic epidermolysis bullosa (EB), result in a significant reduction in quality of life. There is thus a need for novel approache
Externí odkaz:
https://doaj.org/article/dfac4e27a1f3466daebe338d236ee8db
Autor:
Richard J. A. Moakes, Jessica J. Senior, Thomas E. Robinson, Miruna Chipara, Aleksandar Atanasov, Amy Naylor, Anthony D. Metcalfe, Alan M. Smith, Liam M. Grover
Publikováno v:
APL Bioengineering, Vol 7, Iss 2, Pp 029901-029901-1 (2023)
Externí odkaz:
https://doaj.org/article/cdae3640089c4f31a95871dfbe3a277c
Autor:
Helen J. Knowles, Anastasios Chanalaris, Argyro Koutsikouni, Adam P. Cribbs, Liam M. Grover, Philippa A. Hulley
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionFor decades, functional primary human osteocyte cultures have been crucially needed for understanding their role in bone anabolic processes and in endocrine phosphate regulation via the bone-kidney axis. Mature osteocyte proteins (scleros
Externí odkaz:
https://doaj.org/article/f76983696b6b4de29524472273038da5
Autor:
Luke N. Carter, Caroline A. Reed, Alexander P. Morrell, Anthony K. H. Fong, Rayyan Chowdhury, Ewan Miller, Federico Alberini, Balvinder Khambay, Shivana Anand, Liam M. Grover, Trevor Coward, Owen Addison, Sophie C. Cox
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The World Health Organisation has called for a 40% increase in personal protective equipment manufacturing worldwide, recognising that frontline workers need effective protection during the COVID-19 pandemic. Current devices suffer from high
Externí odkaz:
https://doaj.org/article/7b99d48dd89548e3862ee43df95a479e
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-8 (2021)
Chemobrionic materials with applications in tissue engineering can be grown at the interface of calcium and phosphate solutions, however, controlling their dimensions and purity can be difficult. Herein, a flow device allows control of the height and
Externí odkaz:
https://doaj.org/article/b8464cd04a424c859ae9f6a050e3976a
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Abstract The treatment of spinal cord injury (SCI) is a complex challenge in regenerative medicine, complicated by the low intrinsic capacity of CNS neurons to regenerate their axons and the heterogeneity in size, shape and extent of human injuries.
Externí odkaz:
https://doaj.org/article/ffe971d83b1a4a1e90d6c986dabb95c6