Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Liam Chung"'
Autor:
Kevin M. Motz, Ioan A. Lina, Idris Samad, Michael K. Murphy, Madhavi Duvvuri, Ruth J. Davis, Alexander Gelbard, Liam Chung, Yee Chan-Li, Samuel Collins, Jonathan D. Powell, Jennifer H. Elisseeff, Maureen R. Horton, Alexander T. Hillel
Publikováno v:
JCI Insight, Vol 8, Iss 11 (2023)
Laryngotracheal stenosis (LTS) is pathologic fibrotic narrowing of the larynx and trachea characterized by hypermetabolic fibroblasts and CD4+ T cell–mediated inflammation. However, the role of CD4+ T cells in promoting LTS fibrosis is unknown. The
Externí odkaz:
https://doaj.org/article/89ce5a887c6b4f738d6058bd9b2c232a
Autor:
Ying Zheng, Andriana Lebid, Liam Chung, Juan Fu, Xiaoxu Wang, Andrea Otrocol, Jelani C. Zarif, Hong Yu, Nicolas J. Llosa, Drew M. Pardoll
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTActivins, members of the TGF-beta superfamily, have been isolated and identified in the endocrine system, but have not been substantially investigated in the context of the immune system and endocrine-unrelated cancers. Here, we demonstrated
Externí odkaz:
https://doaj.org/article/3c70e25a6b1c4abc8a3c38e2792d5145
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Network controllability asserts a perspective that the structure—the location of edges that connect nodes—of the network contains important information about fundamental characteristics of our ability to change the behavior that evolves
Externí odkaz:
https://doaj.org/article/c3d5da077015480480b43095a1ecba05
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
YAP is a transcriptional coactivator of the Hippo signaling pathway that has largely been studied for its role in the regulation of organ size during development. Several studies have shown that YAP is upregulated in cancer cells, and more recently i
Externí odkaz:
https://doaj.org/article/dd7f726e95fc49b081623008e9387c13
Autor:
Kevin M. Motz, Ioan A. Lina, Idris Samad, Michael K. Murphy, Madhavi Duvvuri, Ruth J. Davis, Alexander Gelbard, Liam Chung, Yee Chan-Li, Samuel Collins, Jonathan D. Powell, Jennifer H. Elisseeff, Maureen R. Horton, Alexander T. Hillel
Publikováno v:
JCI Insight.
Publikováno v:
Cytotherapy. 24:733-741
Most clinically evaluated chimeric antigen receptor (CAR)-based cell therapies are generated from autologous immune cells. However, there are several limitations to autologous cell therapy, including low availability, poor quality of starting cellula
Autor:
Huilin Yang, Umut Y. Ulge, Alfredo Quijano-Rubio, Zachary J. Bernstein, David R. Maestas, Jung-Ho Chun, Wentao Wang, Jian-Xin Lin, Kevin M. Jude, Srujan Singh, Brian T. Orcutt-Jahns, Peng Li, Jody Mou, Liam Chung, Yun-Huai Kuo, Yasmin H. Ali, Aaron S. Meyer, Warren L. Grayson, Nicola M. Heller, K. Christopher Garcia, Warren J. Leonard, Daniel-Adriano Silva, Jennifer H. Elisseeff, David Baker, Jamie B. Spangler
Publikováno v:
Nature Chemical Biology.
Autor:
Cynthia L. Sears, Franck Housseau, Heather M. O'Hagan, Stephen B. Baylin, Robert A. Anders, Sepideh Besharati, Angelo M. De Marzo, Hao Wang, Douglas B. Rusch, Ram Podicheti, Shruthi Sriramkumar, Ashley R. Maiuri, John Michel, Hongni Fan, Christine M. Dejea, June L. Chan, Ada J. Tam, Jessica L. Hicks, Alyssa Wenzel, Liam Chung, James R. White, Christina E. DeStefano Shields
Differential methylation values for methylation-binding domain sequencing (MBDseq) for sham and ETBF-colonized normal epithelium and tumors from Min and BRAFV600ELgr5CreMin (BLM) colons.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::976abf85227f45ce0ca13bee5c61cfa9
https://doi.org/10.1158/2159-8290.22540270.v1
https://doi.org/10.1158/2159-8290.22540270.v1
Autor:
Cynthia L. Sears, Franck Housseau, Heather M. O'Hagan, Stephen B. Baylin, Robert A. Anders, Sepideh Besharati, Angelo M. De Marzo, Hao Wang, Douglas B. Rusch, Ram Podicheti, Shruthi Sriramkumar, Ashley R. Maiuri, John Michel, Hongni Fan, Christine M. Dejea, June L. Chan, Ada J. Tam, Jessica L. Hicks, Alyssa Wenzel, Liam Chung, James R. White, Christina E. DeStefano Shields
Supplementary Figures 1-6; Table S4: Tumors from ETBF-colonized BRAFV600ELgr5CreMin (BLM) mice are MSI negative; Table S6: Primer sequences for qMSP and assays used for Taqman gene expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::836113c42e53c55422cc9c54f512311b
https://doi.org/10.1158/2159-8290.22540276
https://doi.org/10.1158/2159-8290.22540276
Autor:
Cynthia L. Sears, Franck Housseau, Heather M. O'Hagan, Stephen B. Baylin, Robert A. Anders, Sepideh Besharati, Angelo M. De Marzo, Hao Wang, Douglas B. Rusch, Ram Podicheti, Shruthi Sriramkumar, Ashley R. Maiuri, John Michel, Hongni Fan, Christine M. Dejea, June L. Chan, Ada J. Tam, Jessica L. Hicks, Alyssa Wenzel, Liam Chung, James R. White, Christina E. DeStefano Shields
Colorectal cancer is multifaceted, with subtypes defined by genetic, histologic, and immunologic features that are potentially influenced by inflammation, mutagens, and/or microbiota. Colorectal cancers with activating mutations in BRAF are associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a526c0fa8ded8e7a89042195bc05ed
https://doi.org/10.1158/2159-8290.c.6549334
https://doi.org/10.1158/2159-8290.c.6549334