Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Liam Childs"'
Autor:
Alla Bulashevska, Zsófia Nacsa, Franziska Lang, Markus Braun, Martin Machyna, Mustafa Diken, Liam Childs, Renate König
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cancer immunotherapy has witnessed rapid advancement in recent years, with a particular focus on neoantigens as promising targets for personalized treatments. The convergence of immunogenomics, bioinformatics, and artificial intelligence (AI) has pro
Externí odkaz:
https://doaj.org/article/6bac69f6699b4b50b13fc7e5c1602254
Autor:
Filippos T Charitidis, Elham Adabi, Naphang Ho, Angela H Braun, Ciara Tierney, Lisa Strasser, Frederic B Thalheimer, Liam Childs, Jonathan Bones, Colin Clarke, Christian J Buchholz
Publikováno v:
Advanced Science, Vol 10, Iss 35, Pp n/a-n/a (2023)
Abstract Lentiviral vectors (LV) have become the dominant tool for stable gene transfer into lymphocytes including chimeric antigen receptor (CAR) gene delivery to T cells, a major breakthrough in cancer therapy. Yet, room for improvement remains, es
Externí odkaz:
https://doaj.org/article/059f2ee4b5674eeeac1c531a469404a9
Autor:
Robert Lehmann, Liam Childs, Philippe Thomas, Monica Abreu, Luise Fuhr, Hanspeter Herzel, Ulf Leser, Angela Relógio
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126283 (2015)
By regulating the timing of cellular processes, the circadian clock provides a way to adapt physiology and behaviour to the geophysical time. In mammals, a light-entrainable master clock located in the suprachiasmatic nucleus (SCN) controls periphera
Externí odkaz:
https://doaj.org/article/3fa917f5b28c4aca8ddda8aea820dcf9
Publikováno v:
PLoS Genetics, Vol 7, Iss 6, p e1002155 (2011)
The initiation of translation is a fundamental and highly regulated process in gene expression. Translation initiation in prokaryotic systems usually requires interaction between the ribosome and an mRNA sequence upstream of the initiation codon, the
Externí odkaz:
https://doaj.org/article/89043296d91e4aa4b73267dc5026d1a6
Autor:
Brigitte Anliker, Liam Childs, Juliane Rau, Matthias Renner, Silke Schüle, Martina Schuessler-Lenz, Attila Sebe
Publikováno v:
The CRISPR Journal. 5:364-376
Since first proposed as a new tool for gene targeting and genome editing, CRISPR technology has quickly advanced into the clinical stage. Initial studies highlight the potential for CRISPR-Cas9-mediated therapeutic approaches in human medicine to cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b89c67f2bd6d2774d1333ac33815fcf
https://doi.org/10.1089/crispr.2021.0148
https://doi.org/10.1089/crispr.2021.0148
Autor:
Ana-Maria Gätjens-Sanchez, Paulina Richter-Pechanska, Maurice Reimann, Liam Childs, Ruth Flümann, Anna Dolnik, Timon Pablo Hick, Lars Bullinger, Dorothy N. Y. Fan, Dorothee Childs, Kolja Schleich, Clemens A. Schmitt, Jens Schrezenmeier, Sven Maßwig, Andreas Rosenwald, Sophy Denker, Hans Christian Reinhardt, Philipp Lohneis, Antonia Busse, Gero Knittel, Xiurong Cai
Publikováno v:
Blood. 137(20)
Aberrant B-cell receptor/NF-κB signaling is a hallmark feature of B-cell non-Hodgkin lymphomas, especially in diffuse large B-cell lymphoma (DLBCL). Recurrent mutations in this cascade, for example, in CD79B, CARD11, or NFKBIZ, and also in the Toll-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d2ea35f4b519f83104caf014106259
https://pubmed.ncbi.nlm.nih.gov/33232972
https://pubmed.ncbi.nlm.nih.gov/33232972
BackgroundAn increasing number of bioinformatics tools are developed in JavaScript to provide an interactive visual interface to users. However, there are no tools yet that enable fast client-side analysis of large, high-throughput sequencing file fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d2b62800a34fa6019b0a97609a4da6
Publikováno v:
The Plant Journal. 72:115-128
Although our knowledge about the mechanisms of gene expression in chloroplasts has increased substantially over the past decades, next to nothing is known about the signals and factors that govern expression of the plastid genome in non-green tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5381fe3863a994b1e9109eaf101c6a3b
https://doi.org/10.1111/j.1365-313x.2012.05065.x
https://doi.org/10.1111/j.1365-313x.2012.05065.x
Publikováno v:
Plant, Cell & Environment. 35:1860-1878
Arabidopsis thaliana is a geographically widely spread species consisting of local accessions differing both genetically and phenotypically. These differences may constitute environmental adaptations and a latitudinal cline in freezing tolerance has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dfe34cca0b7a69ea82d8adf01f7120e
https://doi.org/10.1111/j.1365-3040.2012.02522.x
https://doi.org/10.1111/j.1365-3040.2012.02522.x
Autor:
Sung-Hyun Kim, Daesik Kim, Sangtae Kim, Sangsu Bae, Jeongbin Park, Gue Ho Hwang, Liam Childs, Jin-Soo Kim
Publikováno v:
Nature Methods. 14:548-549
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7037199d55de262b7cf645548e2de0ce
https://doi.org/10.1038/nmeth.4262
https://doi.org/10.1038/nmeth.4262