Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Liam C. O'Connell"'
Autor:
Liam C. O’Connell, Victoria Johnson, Jessica P. Otis, Anika K. Hutton, Anastasia C. Murthy, Mark C. Liang, Szu-Huan Wang, Nicolas L. Fawzi, Kimberly L. Mowry
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Proteins containing both intrinsically disordered regions (IDRs) and RNA binding domains (RBDs) can phase separate in vitro, forming bodies similar to cellular biomolecular condensates. However, how IDR and RBD domains contribute to in vivo
Externí odkaz:
https://doaj.org/article/ba55eec39d9e48a8bad7b8e990f85b70
Autor:
Liam C. O’Connell, Kimberly L. Mowry
Publikováno v:
Biochem Soc Trans
Subcellular restriction of gene expression is crucial to the functioning of a wide variety of cell types. The cellular machinery driving spatially restricted gene expression has been studied for many years, but recent advances have highlighted novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0352f31b0fd1b013a18fcb35e06d762
https://doi.org/10.1042/bst20210320
https://doi.org/10.1042/bst20210320
Autor:
Liam C. O’Connell, Jessica P. Otis, Erin A. Powrie, Kimberly L. Mowry, Sarah E. Cabral, Christopher R. Neil, Samantha P. Jeschonek, Timothy R. Wood
Publikováno v:
Molecular Biology of the Cell. 32
In Xenopus oocytes, RNAs required for proper germ layer patterning localize to the vegetal cytoplasm in RNP granules, which we have termed localization bodies (L-bodies). In this work, we find that L-bodies are large, biomolecular condensates compose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1dd809571acb80af021348540ce477a
https://doi.org/10.1091/mbc.e21-03-0146-t
https://doi.org/10.1091/mbc.e21-03-0146-t
Autor:
Christopher R, Neil, Samantha P, Jeschonek, Sarah E, Cabral, Liam C, O'Connell, Erin A, Powrie, Jessica P, Otis, Timothy R, Wood, Kimberly L, Mowry
Publikováno v:
Molecular biology of the cell. 32(22)
Ribonucleoprotein (RNP) granules are membraneless compartments within cells, formed by phase separation, that function as regulatory hubs for diverse biological processes. However, the mechanisms by which RNAs and proteins interact to promote RNP gra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::240fe7128859ad6df4c38a9b94f8753a
https://pubmed.ncbi.nlm.nih.gov/34613784
https://pubmed.ncbi.nlm.nih.gov/34613784
Autor:
Liam C. O’Connell, Christopher R. Neil, Samantha P. Jeschonek, Erin A. Powrie, Timothy A. Wood, Sarah E. Cabral, Kimberly L. Mowry
RNP granules are membrane-less compartments within cells, formed by phase separation, that function as regulatory hubs for diverse biological processes. However, the mechanisms by which RNAs and proteins interact to promote RNP granule structure and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8724400489364c284f1a8a8c4063d262
https://doi.org/10.1101/2020.05.08.084814
https://doi.org/10.1101/2020.05.08.084814
Autor:
Christopher R. Neil, Timothy A. Wood, Erin A. Powrie, Kimberly L. Mowry, Samantha P. Jeschonek, Liam C. O’Connell, Sarah E. Cabral
Publikováno v:
SSRN Electronic Journal.
RNP granules are membrane-less compartments within cells, formed by phase separation, that function as regulatory hubs for diverse biological processes. However, the mechanisms by which RNAs and proteins interact to promote RNP granule structure and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::562501f9c965569f802d82629390b8bb
https://doi.org/10.2139/ssrn.3550248
https://doi.org/10.2139/ssrn.3550248
Autor:
Nipam H. Patel, Heather S. Bruce, Julia Serano, Jennifer Wang, Arnaud Martin, Erin Jarvis, Carryn A. Barker, Shagnik Ray, Liam C. O’Connell
Publikováno v:
Current Biology. 26(1):14-26
Crustaceans possess a diverse array of specialized limbs. Although shifts in Hox gene expression domains have been postulated to play a role in generating this limb diversity, little functional data have been provided to understand the precise roles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb87b024a86a609d004b80fc5e3b60a
Autor:
Jane F. Desforges, Liam C. O’Connell
Publikováno v:
Blood. 10:802-811
Serial studies revealed characteristic changes in the peripheral blood of infants with erythroblastosis fetalis. In the presence of elevated nucleated red cells and reticulocytosis, replacement transfusion brought about a momentary decline to normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::396a6361a437eac6960e806ced5675b4
https://doi.org/10.1182/blood.v10.8.802.802
https://doi.org/10.1182/blood.v10.8.802.802